137 related articles for article (PubMed ID: 16135660)
1. Pathways of carbamazepine bioactivation in vitro: II. The role of human cytochrome P450 enzymes in the formation of 2-hydroxyiminostilbene.
Pearce RE; Uetrecht JP; Leeder JS
Drug Metab Dispos; 2005 Dec; 33(12):1819-26. PubMed ID: 16135660
[TBL] [Abstract][Full Text] [Related]
2. Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine.
Pearce RE; Lu W; Wang Y; Uetrecht JP; Correia MA; Leeder JS
Drug Metab Dispos; 2008 Aug; 36(8):1637-49. PubMed ID: 18463198
[TBL] [Abstract][Full Text] [Related]
3. Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites.
Pearce RE; Vakkalagadda GR; Leeder JS
Drug Metab Dispos; 2002 Nov; 30(11):1170-9. PubMed ID: 12386121
[TBL] [Abstract][Full Text] [Related]
4. Identification of primary and sequential bioactivation pathways of carbamazepine in human liver microsomes using liquid chromatography/tandem mass spectrometry.
Bu HZ; Zhao P; Dalvie DK; Pool WF
Rapid Commun Mass Spectrom; 2007; 21(20):3317-22. PubMed ID: 17879390
[TBL] [Abstract][Full Text] [Related]
5. Detection of 2-hydroxyiminostilbene in the urine of patients taking carbamazepine and its oxidation to a reactive iminoquinone intermediate.
Ju C; Uetrecht JP
J Pharmacol Exp Ther; 1999 Jan; 288(1):51-6. PubMed ID: 9862752
[TBL] [Abstract][Full Text] [Related]
6. The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.
Gallagher EP; Kunze KL; Stapleton PL; Eaton DL
Toxicol Appl Pharmacol; 1996 Dec; 141(2):595-606. PubMed ID: 8975785
[TBL] [Abstract][Full Text] [Related]
7. CYP3A4-Mediated carbamazepine (CBZ) metabolism: formation of a covalent CBZ-CYP3A4 adduct and alteration of the enzyme kinetic profile.
Kang P; Liao M; Wester MR; Leeder JS; Pearce RE; Correia MA
Drug Metab Dispos; 2008 Mar; 36(3):490-9. PubMed ID: 18096676
[TBL] [Abstract][Full Text] [Related]
8. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.
Kazui M; Nishiya Y; Ishizuka T; Hagihara K; Farid NA; Okazaki O; Ikeda T; Kurihara A
Drug Metab Dispos; 2010 Jan; 38(1):92-9. PubMed ID: 19812348
[TBL] [Abstract][Full Text] [Related]
9. Differential selectivity in carbamazepine-induced inactivation of cytochrome P450 enzymes in rat and human liver.
Masubuchi Y; Nakano T; Ose A; Horie T
Arch Toxicol; 2001 Nov; 75(9):538-43. PubMed ID: 11760814
[TBL] [Abstract][Full Text] [Related]
10. Human in vitro glutathionyl and protein adducts of carbamazepine-10,11-epoxide, a stable and pharmacologically active metabolite of carbamazepine.
Bu HZ; Kang P; Deese AJ; Zhao P; Pool WF
Drug Metab Dispos; 2005 Dec; 33(12):1920-4. PubMed ID: 16204461
[TBL] [Abstract][Full Text] [Related]
11. CYP3A4 and CYP3A7-mediated carbamazepine 10,11-epoxidation are activated by differential endogenous steroids.
Nakamura H; Torimoto N; Ishii I; Ariyoshi N; Nakasa H; Ohmori S; Kitada M
Drug Metab Dispos; 2003 Apr; 31(4):432-8. PubMed ID: 12642469
[TBL] [Abstract][Full Text] [Related]
12. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
Madan A; Parkinson A; Faiman MD
Alcohol Clin Exp Res; 1998 Sep; 22(6):1212-9. PubMed ID: 9756035
[TBL] [Abstract][Full Text] [Related]
13. Metabolic activation of nevirapine in human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4.
Wen B; Chen Y; Fitch WL
Drug Metab Dispos; 2009 Jul; 37(7):1557-62. PubMed ID: 19364830
[TBL] [Abstract][Full Text] [Related]
14. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.
Pearce RE; Gotschall RR; Kearns GL; Leeder JS
Drug Metab Dispos; 2001 Dec; 29(12):1548-54. PubMed ID: 11717173
[TBL] [Abstract][Full Text] [Related]
15. In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism.
Yu J; Brown DG; Burdette D
Drug Metab Dispos; 2010 Oct; 38(10):1767-78. PubMed ID: 20595377
[TBL] [Abstract][Full Text] [Related]
16. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib.
Towles JK; Clark RN; Wahlin MD; Uttamsingh V; Rettie AE; Jackson KD
Drug Metab Dispos; 2016 Oct; 44(10):1584-97. PubMed ID: 27450182
[TBL] [Abstract][Full Text] [Related]
17. Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study.
Ghosh C; Hossain M; Spriggs A; Ghosh A; Grant GA; Marchi N; Perucca E; Janigro D
Epilepsia; 2015 Mar; 56(3):439-49. PubMed ID: 25656284
[TBL] [Abstract][Full Text] [Related]
18. The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver microsomes.
Pirmohamed M; Kitteringham NR; Breckenridge AM; Park BK
Biochem Pharmacol; 1992 Dec; 44(12):2307-14. PubMed ID: 1472096
[TBL] [Abstract][Full Text] [Related]
19. Characterization of human cytochrome P450s involved in the bioactivation of clozapine.
Dragovic S; Gunness P; Ingelman-Sundberg M; Vermeulen NP; Commandeur JN
Drug Metab Dispos; 2013 Mar; 41(3):651-8. PubMed ID: 23297297
[TBL] [Abstract][Full Text] [Related]
20. One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac.
Boerma JS; Vermeulen NP; Commandeur JN
Chem Biol Interact; 2014 Jan; 207():32-40. PubMed ID: 24246759
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
