BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1180 related articles for article (PubMed ID: 16136078)

  • 1. Vertebrate Smoothened functions at the primary cilium.
    Corbit KC; Aanstad P; Singla V; Norman AR; Stainier DY; Reiter JF
    Nature; 2005 Oct; 437(7061):1018-21. PubMed ID: 16136078
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.
    Peluso MO; Campbell VT; Harari JA; Tibbitts TT; Proctor JL; Whitebread N; Conley JM; White KF; Kutok JL; Read MA; McGovern K; Faia KL
    PLoS One; 2014; 9(3):e90534. PubMed ID: 24608250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation.
    Wang Y; Zhou Z; Walsh CT; McMahon AP
    Proc Natl Acad Sci U S A; 2009 Feb; 106(8):2623-8. PubMed ID: 19196978
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.
    Wilson CW; Chen MH; Chuang PT
    PLoS One; 2009; 4(4):e5182. PubMed ID: 19365551
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling.
    Aanstad P; Santos N; Corbit KC; Scherz PJ; Trinh le A; Salvenmoser W; Huisken J; Reiter JF; Stainier DY
    Curr Biol; 2009 Jun; 19(12):1034-9. PubMed ID: 19464178
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium.
    Bijlsma MF; Damhofer H; Roelink H
    Sci Signal; 2012 Aug; 5(238):ra60. PubMed ID: 22912493
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.
    Jung B; Padula D; Burtscher I; Landerer C; Lutter D; Theis F; Messias AC; Geerlof A; Sattler M; Kremmer E; Boldt K; Ueffing M; Lickert H
    PLoS One; 2016; 11(2):e0149477. PubMed ID: 26901434
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hedgehog Signaling Regulates the Ciliary Transport of Odorant Receptors in Drosophila.
    Sanchez GM; Alkhori L; Hatano E; Schultz SW; Kuzhandaivel A; Jafari S; Granseth B; Alenius M
    Cell Rep; 2016 Jan; 14(3):464-470. PubMed ID: 26774485
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.
    Li S; Li S; Han Y; Tong C; Wang B; Chen Y; Jiang J
    PLoS Biol; 2016 Jun; 14(6):e1002481. PubMed ID: 27280464
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.
    Chong YC; Mann RK; Zhao C; Kato M; Beachy PA
    Genes Dev; 2015 Feb; 29(3):262-76. PubMed ID: 25644602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The primary cilium as a Hedgehog signal transduction machine.
    Goetz SC; Ocbina PJ; Anderson KV
    Methods Cell Biol; 2009; 94():199-222. PubMed ID: 20362092
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.
    Wang Y; Arvanites AC; Davidow L; Blanchard J; Lam K; Yoo JW; Coy S; Rubin LL; McMahon AP
    ACS Chem Biol; 2012 Jun; 7(6):1040-8. PubMed ID: 22554036
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.
    Chen Y; Sasai N; Ma G; Yue T; Jia J; Briscoe J; Jiang J
    PLoS Biol; 2011 Jun; 9(6):e1001083. PubMed ID: 21695114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis.
    Wu VM; Chen SC; Arkin MR; Reiter JF
    Proc Natl Acad Sci U S A; 2012 Aug; 109(34):13644-9. PubMed ID: 22864913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.
    Barakat B; Yu L; Lo C; Vu D; De Luca E; Cain JE; Martelotto LG; Dedhar S; Sadler AJ; Wang D; Watkins DN; Hannigan GE
    EMBO Rep; 2013 Sep; 14(9):837-44. PubMed ID: 23877428
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cilia-mediated hedgehog signaling in Drosophila.
    Kuzhandaivel A; Schultz SW; Alkhori L; Alenius M
    Cell Rep; 2014 May; 7(3):672-80. PubMed ID: 24768000
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2.
    Yang C; Chen W; Chen Y; Jiang J
    Cell Res; 2012 Nov; 22(11):1593-604. PubMed ID: 22986504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus.
    Kim J; Kato M; Beachy PA
    Proc Natl Acad Sci U S A; 2009 Dec; 106(51):21666-71. PubMed ID: 19996169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.
    Bijlsma MF; Spek CA; Zivkovic D; van de Water S; Rezaee F; Peppelenbosch MP
    PLoS Biol; 2006 Jul; 4(8):e232. PubMed ID: 16895439
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 59.