189 related articles for article (PubMed ID: 16136593)
1. Fermentation, purification, formulation, and pharmacological evaluation of a prolyl endopeptidase from Myxococcus xanthus: implications for Celiac Sprue therapy.
Gass J; Ehren J; Strohmeier G; Isaacs I; Khosla C
Biotechnol Bioeng; 2005 Dec; 92(6):674-84. PubMed ID: 16136593
[TBL] [Abstract][Full Text] [Related]
2. Combination enzyme therapy for gastric digestion of dietary gluten in patients with celiac sprue.
Gass J; Bethune MT; Siegel M; Spencer A; Khosla C
Gastroenterology; 2007 Aug; 133(2):472-80. PubMed ID: 17681168
[TBL] [Abstract][Full Text] [Related]
3. A scaleable manufacturing process for pro-EP-B2, a cysteine protease from barley indicated for celiac sprue.
Vora H; McIntire J; Kumar P; Deshpande M; Khosla C
Biotechnol Bioeng; 2007 Sep; 98(1):177-85. PubMed ID: 17385743
[TBL] [Abstract][Full Text] [Related]
4. Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue.
Shan L; Marti T; Sollid LM; Gray GM; Khosla C
Biochem J; 2004 Oct; 383(Pt 2):311-8. PubMed ID: 15245330
[TBL] [Abstract][Full Text] [Related]
5. Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease.
Stepniak D; Spaenij-Dekking L; Mitea C; Moester M; de Ru A; Baak-Pablo R; van Veelen P; Edens L; Koning F
Am J Physiol Gastrointest Liver Physiol; 2006 Oct; 291(4):G621-9. PubMed ID: 16690904
[TBL] [Abstract][Full Text] [Related]
6. Rational design of combination enzyme therapy for celiac sprue.
Siegel M; Bethune MT; Gass J; Ehren J; Xia J; Johannsen A; Stuge TB; Gray GM; Lee PP; Khosla C
Chem Biol; 2006 Jun; 13(6):649-58. PubMed ID: 16793522
[TBL] [Abstract][Full Text] [Related]
7. A new microbial gluten-degrading prolyl endopeptidase: Potential application in celiac disease to reduce gluten immunogenic peptides.
Moreno Amador ML; Arévalo-Rodríguez M; Durán EM; Martínez Reyes JC; Sousa Martín C
PLoS One; 2019; 14(6):e0218346. PubMed ID: 31246975
[TBL] [Abstract][Full Text] [Related]
8. Effect of barley endoprotease EP-B2 on gluten digestion in the intact rat.
Gass J; Vora H; Bethune MT; Gray GM; Khosla C
J Pharmacol Exp Ther; 2006 Sep; 318(3):1178-86. PubMed ID: 16757540
[TBL] [Abstract][Full Text] [Related]
9. Prolyl endopeptidase-mediated destruction of T cell epitopes in whole gluten: chemical and immunological characterization.
Marti T; Molberg O; Li Q; Gray GM; Khosla C; Sollid LM
J Pharmacol Exp Ther; 2005 Jan; 312(1):19-26. PubMed ID: 15358813
[TBL] [Abstract][Full Text] [Related]
10. Generation of food-grade recombinant Lactobacillus casei delivering Myxococcus xanthus prolyl endopeptidase.
Alvarez-Sieiro P; Martin MC; Redruello B; Del Rio B; Ladero V; Palanski BA; Khosla C; Fernandez M; Alvarez MA
Appl Microbiol Biotechnol; 2014 Aug; 98(15):6689-700. PubMed ID: 24752841
[TBL] [Abstract][Full Text] [Related]
11. Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: implications for coeliac disease.
Mitea C; Havenaar R; Drijfhout JW; Edens L; Dekking L; Koning F
Gut; 2008 Jan; 57(1):25-32. PubMed ID: 17494108
[TBL] [Abstract][Full Text] [Related]
12. In vivo fluorescence imaging of exogenous enzyme activity in the gastrointestinal tract.
Fuhrmann G; Leroux JC
Proc Natl Acad Sci U S A; 2011 May; 108(22):9032-7. PubMed ID: 21576491
[TBL] [Abstract][Full Text] [Related]
13. Limited efficiency of prolyl-endopeptidase in the detoxification of gliadin peptides in celiac disease.
Matysiak-Budnik T; Candalh C; Cellier C; Dugave C; Namane A; Vidal-Martinez T; Cerf-Bensussan N; Heyman M
Gastroenterology; 2005 Sep; 129(3):786-96. PubMed ID: 16143118
[TBL] [Abstract][Full Text] [Related]
14. Protein engineering of improved prolyl endopeptidases for celiac sprue therapy.
Ehren J; Govindarajan S; Morón B; Minshull J; Khosla C
Protein Eng Des Sel; 2008 Dec; 21(12):699-707. PubMed ID: 18836204
[TBL] [Abstract][Full Text] [Related]
15. Effect of prolyl endopeptidase on digestive-resistant gliadin peptides in vivo.
Piper JL; Gray GM; Khosla C
J Pharmacol Exp Ther; 2004 Oct; 311(1):213-9. PubMed ID: 15143130
[TBL] [Abstract][Full Text] [Related]
16. Consumption of gluten with gluten-degrading enzyme by celiac patients: a pilot-study.
Tack GJ; van de Water JM; Bruins MJ; Kooy-Winkelaar EM; van Bergen J; Bonnet P; Vreugdenhil AC; Korponay-Szabo I; Edens L; von Blomberg BM; Schreurs MW; Mulder CJ; Koning F
World J Gastroenterol; 2013 Sep; 19(35):5837-47. PubMed ID: 24124328
[TBL] [Abstract][Full Text] [Related]
17. Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue.
Shan L; Qiao SW; Arentz-Hansen H; Molberg Ø; Gray GM; Sollid LM; Khosla C
J Proteome Res; 2005; 4(5):1732-41. PubMed ID: 16212427
[TBL] [Abstract][Full Text] [Related]
18. A propeptide toolbox for secretion optimization of Flavobacterium meningosepticum endopeptidase in Lactococcus lactis.
Lim PY; Tan LL; Ow DS; Wong FT
Microb Cell Fact; 2017 Dec; 16(1):221. PubMed ID: 29207979
[TBL] [Abstract][Full Text] [Related]
19. Development of wheat genotypes expressing a glutamine-specific endoprotease from barley and a prolyl endopeptidase from Flavobacterium meningosepticum or Pyrococcus furiosus as a potential remedy to celiac disease.
Osorio CE; Wen N; Mejias JH; Liu B; Reinbothe S; von Wettstein D; Rustgi S
Funct Integr Genomics; 2019 Jan; 19(1):123-136. PubMed ID: 30159724
[TBL] [Abstract][Full Text] [Related]
20. Purification, characterization and the use of recombinant prolyl oligopeptidase from Myxococcus xanthus for gluten hydrolysis.
Kocadag Kocazorbaz E; Zihnioglu F
Protein Expr Purif; 2017 Jan; 129():101-107. PubMed ID: 27693621
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
