BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

10319 related articles for article (PubMed ID: 1613753)

  • 1. Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
    Cushman M; Nagarathnam D; Gopal D; He HM; Lin CM; Hamel E
    J Med Chem; 1992 Jun; 35(12):2293-306. PubMed ID: 1613753
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
    Cushman M; Nagarathnam D; Gopal D; Chakraborti AK; Lin CM; Hamel E
    J Med Chem; 1991 Aug; 34(8):2579-88. PubMed ID: 1875350
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
    Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents.
    Madadi NR; Penthala NR; Ketkar A; Eoff RL; Trujullo-Alonso V; Guzman ML; Crooks PA
    Anticancer Agents Med Chem; 2018; 18(4):556-564. PubMed ID: 28403783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A.
    Mu F; Hamel E; Lee DJ; Pryor DE; Cushman M
    J Med Chem; 2003 Apr; 46(9):1670-82. PubMed ID: 12699385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
    Pettit GR; Rhodes MR; Herald DL; Hamel E; Schmidt JM; Pettit RK
    J Med Chem; 2005 Jun; 48(12):4087-99. PubMed ID: 15943482
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of a series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization.
    Cushman M; He HM; Lin CM; Hamel E
    J Med Chem; 1993 Sep; 36(19):2817-21. PubMed ID: 8410995
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
    Nakamura M; Kajita D; Matsumoto Y; Hashimoto Y
    Bioorg Med Chem; 2013 Dec; 21(23):7381-91. PubMed ID: 24139940
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
    Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of aryl azide derivatives of combretastatin A-4 as molecular probes for tubulin.
    Pinney KG; Mejia MP; Villalobos VM; Rosenquist BE; Pettit GR; Verdier-Pinard P; Hamel E
    Bioorg Med Chem; 2000 Oct; 8(10):2417-25. PubMed ID: 11058036
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
    Kuo SC; Lee HZ; Juang JP; Lin YT; Wu TS; Chang JJ; Lednicer D; Paull KD; Lin CM; Hamel E
    J Med Chem; 1993 Apr; 36(9):1146-56. PubMed ID: 8387598
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation.
    Borrel C; Thoret S; Cachet X; Guénard D; Tillequin F; Koch M; Michel S
    Bioorg Med Chem; 2005 Jun; 13(11):3853-64. PubMed ID: 15863010
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K; Hentzen J; dit Chabert JF; Ducki S; Gani OA; Sylte I; Skrede M; Flørenes VA; Hansen TV
    Bioorg Med Chem; 2008 May; 16(9):4829-38. PubMed ID: 18396050
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
    Duan YT; Man RJ; Tang DJ; Yao YF; Tao XX; Yu C; Liang XY; Makawana JA; Zou MJ; Wang ZC; Zhu HL
    Sci Rep; 2016 May; 6():25387. PubMed ID: 27138035
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents.
    Liou JP; Chang JY; Chang CW; Chang CY; Mahindroo N; Kuo FM; Hsieh HP
    J Med Chem; 2004 May; 47(11):2897-905. PubMed ID: 15139768
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM; Singh SB; Chu PS; Dempcy RO; Schmidt JM; Pettit GR; Hamel E
    Mol Pharmacol; 1988 Aug; 34(2):200-8. PubMed ID: 3412321
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
    Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.
    Gwaltney SL; Imade HM; Barr KJ; Li Q; Gehrke L; Credo RB; Warner RB; Lee JY; Kovar P; Wang J; Nukkala MA; Zielinski NA; Frost D; Ng SC; Sham HL
    Bioorg Med Chem Lett; 2001 Apr; 11(7):871-4. PubMed ID: 11294380
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors.
    Shobeiri N; Rashedi M; Mosaffa F; Zarghi A; Ghandadi M; Ghasemi A; Ghodsi R
    Eur J Med Chem; 2016 May; 114():14-23. PubMed ID: 26974371
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 516.