BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

350 related articles for article (PubMed ID: 16140212)

  • 1. NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.
    Callapina M; Zhou J; Schmid T; Köhl R; Brüne B
    Free Radic Biol Med; 2005 Oct; 39(7):925-36. PubMed ID: 16140212
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.
    Callapina M; Zhou J; Schnitzer S; Metzen E; Lohr C; Deitmer JW; Brüne B
    Exp Cell Res; 2005 May; 306(1):274-84. PubMed ID: 15878351
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1alpha stabilization.
    Köhl R; Zhou J; Brüne B
    Free Radic Biol Med; 2006 Apr; 40(8):1430-42. PubMed ID: 16631533
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calpain mediates a von Hippel-Lindau protein-independent destruction of hypoxia-inducible factor-1alpha.
    Zhou J; Köhl R; Herr B; Frank R; Brüne B
    Mol Biol Cell; 2006 Apr; 17(4):1549-58. PubMed ID: 16421254
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases.
    Metzen E; Zhou J; Jelkmann W; Fandrey J; Brüne B
    Mol Biol Cell; 2003 Aug; 14(8):3470-81. PubMed ID: 12925778
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
    Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
    EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.
    Lee HY; Lee T; Lee N; Yang EG; Lee C; Lee J; Moon EY; Ha J; Park H
    Carcinogenesis; 2011 May; 32(5):703-12. PubMed ID: 21335603
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nitric oxide and superoxide: interference with hypoxic signaling.
    Brüne B; Zhou J
    Cardiovasc Res; 2007 Jul; 75(2):275-82. PubMed ID: 17412315
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro.
    Pan Y; Mansfield KD; Bertozzi CC; Rudenko V; Chan DA; Giaccia AJ; Simon MC
    Mol Cell Biol; 2007 Feb; 27(3):912-25. PubMed ID: 17101781
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity.
    Li YN; Xi MM; Guo Y; Hai CX; Yang WL; Qin XJ
    Toxicol Lett; 2014 Jan; 224(2):165-74. PubMed ID: 24188932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
    Pereira T; Zheng X; Ruas JL; Tanimoto K; Poellinger L
    J Biol Chem; 2003 Feb; 278(9):6816-23. PubMed ID: 12468553
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
    Park YK; Ahn DR; Oh M; Lee T; Yang EG; Son M; Park H
    Mol Pharmacol; 2008 Jul; 74(1):236-45. PubMed ID: 18426857
    [TBL] [Abstract][Full Text] [Related]  

  • 13. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
    Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
    Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
    Jaakkola P; Mole DR; Tian YM; Wilson MI; Gielbert J; Gaskell SJ; von Kriegsheim A; Hebestreit HF; Mukherji M; Schofield CJ; Maxwell PH; Pugh CW; Ratcliffe PJ
    Science; 2001 Apr; 292(5516):468-72. PubMed ID: 11292861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
    André H; Pereira TS
    J Biol Chem; 2008 Oct; 283(43):29375-84. PubMed ID: 18694926
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oxygen-sensing under the influence of nitric oxide.
    Berchner-Pfannschmidt U; Tug S; Kirsch M; Fandrey J
    Cell Signal; 2010 Mar; 22(3):349-56. PubMed ID: 19861159
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.
    Qian H; Zou Y; Tang Y; Gong Y; Qian Z; Wei G; Zhang Q
    Phys Chem Chem Phys; 2018 Jul; 20(27):18756-18765. PubMed ID: 29961792
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1α stabilization in colon carcinoma cells.
    Chowdhury R; Godoy LC; Thiantanawat A; Trudel LJ; Deen WM; Wogan GN
    Chem Res Toxicol; 2012 Oct; 25(10):2194-202. PubMed ID: 22971010
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
    Kageyama Y; Koshiji M; To KK; Tian YM; Ratcliffe PJ; Huang LE
    FASEB J; 2004 Jun; 18(9):1028-30. PubMed ID: 15084514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reactive oxygen species produced by the knockdown of manganese-superoxide dismutase up-regulate hypoxia-inducible factor-1alpha expression in oral squamous cell carcinoma cells.
    Sasabe E; Yang Z; Ohno S; Yamamoto T
    Free Radic Biol Med; 2010 May; 48(10):1321-9. PubMed ID: 20188165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.