These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 16141322)

  • 1. Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation.
    Iwata A; Christianson JC; Bucci M; Ellerby LM; Nukina N; Forno LS; Kopito RR
    Proc Natl Acad Sci U S A; 2005 Sep; 102(37):13135-40. PubMed ID: 16141322
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.
    Iwata A; Riley BE; Johnston JA; Kopito RR
    J Biol Chem; 2005 Dec; 280(48):40282-92. PubMed ID: 16192271
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential effects of polyglutamine proteins on nuclear organization and artificial reporter splicing.
    Sun J; Xu H; Negi S; Subramony SH; Hebert MD
    J Neurosci Res; 2007 Aug; 85(11):2306-17. PubMed ID: 17526020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Huntingtin processing in pathogenesis of Huntington disease.
    Qin ZH; Gu ZL
    Acta Pharmacol Sin; 2004 Oct; 25(10):1243-9. PubMed ID: 15456523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
    Cummings CJ; Orr HT; Zoghbi HY
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1079-81. PubMed ID: 10434309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FAT10 protein binds to polyglutamine proteins and modulates their solubility.
    Nagashima Y; Kowa H; Tsuji S; Iwata A
    J Biol Chem; 2011 Aug; 286(34):29594-600. PubMed ID: 21757738
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal.
    Riley BE; Zoghbi HY; Orr HT
    J Biol Chem; 2005 Jun; 280(23):21942-8. PubMed ID: 15824120
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polyglutamine expansion accelerates the dynamics of ataxin-1 and does not result in aggregate formation.
    Krol HA; Krawczyk PM; Bosch KS; Aten JA; Hol EM; Reits EA
    PLoS One; 2008 Jan; 3(1):e1503. PubMed ID: 18231590
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract.
    Hazeki N; Nakamura K; Goto J; Kanazawa I
    Biochem Biophys Res Commun; 1999 Mar; 256(2):361-6. PubMed ID: 10079189
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuropathological staging of spinocerebellar ataxia type 2 by semiquantitative 1C2-positive neuron typing. Nuclear translocation of cytoplasmic 1C2 underlies disease progression of spinocerebellar ataxia type 2.
    Koyano S; Yagishita S; Kuroiwa Y; Tanaka F; Uchihara T
    Brain Pathol; 2014 Nov; 24(6):599-606. PubMed ID: 24674145
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Focal distortion of the nuclear envelope by huntingtin aggregates revealed by lamin immunostaining.
    Chapple JP; Bros-Facer V; Butler R; Gallo JM
    Neurosci Lett; 2008 Dec; 447(2-3):172-4. PubMed ID: 18840504
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death.
    Bjørkøy G; Lamark T; Brech A; Outzen H; Perander M; Overvatn A; Stenmark H; Johansen T
    J Cell Biol; 2005 Nov; 171(4):603-14. PubMed ID: 16286508
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.
    Ralser M; Nonhoff U; Albrecht M; Lengauer T; Wanker EE; Lehrach H; Krobitsch S
    Hum Mol Genet; 2005 Oct; 14(19):2893-909. PubMed ID: 16115810
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1.
    Vig PJ; Wei J; Shao Q; Hebert MD; Subramony SH; Sutton LT
    Neurosci Lett; 2007 Jun; 420(1):53-7. PubMed ID: 17442486
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HAP1 can sequester a subset of TBP in cytoplasmic inclusions via specific interaction with the conserved TBP(CORE).
    Prigge JR; Schmidt EE
    BMC Mol Biol; 2007 Sep; 8():76. PubMed ID: 17868456
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.
    Kegel KB; Kim M; Sapp E; McIntyre C; Castaño JG; Aronin N; DiFiglia M
    J Neurosci; 2000 Oct; 20(19):7268-78. PubMed ID: 11007884
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity.
    Kaytor MD; Wilkinson KD; Warren ST
    J Neurochem; 2004 May; 89(4):962-73. PubMed ID: 15140195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hsp70/Hsc70 regulates the effect phosphorylation has on stabilizing ataxin-1.
    Jorgensen ND; Andresen JM; Pitt JE; Swenson MA; Zoghbi HY; Orr HT
    J Neurochem; 2007 Sep; 102(6):2040-2048. PubMed ID: 17540008
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SUMO-1 interacts with mutant ataxin-1 and colocalizes to its aggregates in Purkinje cells of SCA1 transgenic mice.
    Kang S; Hong S
    Arch Ital Biol; 2010 Dec; 148(4):351-63. PubMed ID: 21308649
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
    Atwal RS; Xia J; Pinchev D; Taylor J; Epand RM; Truant R
    Hum Mol Genet; 2007 Nov; 16(21):2600-15. PubMed ID: 17704510
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.