BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 16141606)

  • 1. The effects of culture conditions on CYP3A4 and MDR1 mRNA induction by 1alpha,25-dihydroxyvitamin D(3) in human intestinal cell lines, Caco-2 and LS180.
    Aiba T; Susa M; Fukumori S; Hashimoto Y
    Drug Metab Pharmacokinet; 2005 Aug; 20(4):268-74. PubMed ID: 16141606
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.
    Pfrunder A; Gutmann H; Beglinger C; Drewe J
    J Pharm Pharmacol; 2003 Jan; 55(1):59-66. PubMed ID: 12625868
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies.
    Engman HA; Lennernäs H; Taipalensuu J; Otter C; Leidvik B; Artursson P
    J Pharm Sci; 2001 Nov; 90(11):1736-51. PubMed ID: 11745731
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Influence of drugs and nutrients on transporter gene expression levels in Caco-2 and LS180 intestinal epithelial cell lines.
    Li Q; Sai Y; Kato Y; Tamai I; Tsuji A
    Pharm Res; 2003 Aug; 20(8):1119-24. PubMed ID: 12948007
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.
    Thummel KE; Brimer C; Yasuda K; Thottassery J; Senn T; Lin Y; Ishizuka H; Kharasch E; Schuetz J; Schuetz E
    Mol Pharmacol; 2001 Dec; 60(6):1399-406. PubMed ID: 11723248
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.
    Fukumori S; Murata T; Taguchi M; Hashimoto Y
    Drug Metab Pharmacokinet; 2007 Oct; 22(5):377-81. PubMed ID: 17965521
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transport of 5,5-diphenylbarbituric acid and its precursors and their effect on P-gp, MRP2 and CYP3A4 in Caco-2 and LS180 cells.
    Fan J; Maeng HJ; Du Y; Kwan D; Pang KS
    Eur J Pharm Sci; 2011 Jan; 42(1-2):19-29. PubMed ID: 20955791
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.
    Schmiedlin-Ren P; Thummel KE; Fisher JM; Paine MF; Watkins PB
    Drug Metab Dispos; 2001 Nov; 29(11):1446-53. PubMed ID: 11602520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity.
    Patel J; Buddha B; Dey S; Pal D; Mitra AK
    Am J Ther; 2004; 11(4):262-77. PubMed ID: 15266218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
    Becquemont L; Glaeser H; Drescher S; Hitzl M; Simon N; Murdter TE; Heinkele G; Hofmann U; Schaefer C; Burk O; Verstuyft C; Eichelbaum M; Fromm MF
    Clin Pharmacol Ther; 2006 May; 79(5):449-60. PubMed ID: 16678547
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypericum perforatum: which constituents may induce intestinal MDR1 and CYP3A4 mRNA expression?
    Gutmann H; Poller B; Büter KB; Pfrunder A; Schaffner W; Drewe J
    Planta Med; 2006 Jun; 72(8):685-90. PubMed ID: 16755466
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
    Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
    Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.
    Yamaura Y; Chapron BD; Wang Z; Himmelfarb J; Thummel KE
    Drug Metab Dispos; 2016 Mar; 44(3):329-35. PubMed ID: 26700954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
    Cummins CL; Mangravite LM; Benet LZ
    Pharm Res; 2001 Aug; 18(8):1102-9. PubMed ID: 11587480
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of CYP3A4 by 1alpha,25-dyhydroxyvitamin D3 in HepG2 cells.
    Elizondo G; Medina-Díaz IM
    Life Sci; 2003 May; 73(2):141-9. PubMed ID: 12738030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of Curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180.
    Graber-Maier A; Büter KB; Aeschlimann J; Bittel C; Kreuter M; Drewe J; Gutmann H
    Planta Med; 2010 Nov; 76(16):1866-70. PubMed ID: 20509107
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of budesonide on P-glycoprotein expression in intestinal cell lines.
    Maier A; Zimmermann C; Beglinger C; Drewe J; Gutmann H
    Br J Pharmacol; 2007 Feb; 150(3):361-8. PubMed ID: 17179942
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein.
    Brimer C; Dalton JT; Zhu Z; Schuetz J; Yasuda K; Vanin E; Relling MV; Lu Y; Schuetz EG
    Pharm Res; 2000 Jul; 17(7):803-10. PubMed ID: 10990198
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.
    Schmiedlin-Ren P; Thummel KE; Fisher JM; Paine MF; Lown KS; Watkins PB
    Mol Pharmacol; 1997 May; 51(5):741-54. PubMed ID: 9145912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human PXR-mediated induction of intestinal CYP3A4 attenuates 1α,25-dihydroxyvitamin D₃ function in human colon adenocarcinoma LS180 cells.
    Zheng XE; Wang Z; Liao MZ; Lin YS; Shuhart MC; Schuetz EG; Thummel KE
    Biochem Pharmacol; 2012 Aug; 84(3):391-401. PubMed ID: 22562045
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.