BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

382 related articles for article (PubMed ID: 16143138)

  • 1. Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.
    Howlett M; Judd LM; Jenkins B; La Gruta NL; Grail D; Ernst M; Giraud AS
    Gastroenterology; 2005 Sep; 129(3):1005-18. PubMed ID: 16143138
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development.
    Howlett M; Giraud AS; Lescesen H; Jackson CB; Kalantzis A; Van Driel IR; Robb L; Van der Hoek M; Ernst M; Minamoto T; Boussioutas A; Oshima H; Oshima M; Judd LM
    Gastroenterology; 2009 Mar; 136(3):967-77. PubMed ID: 19121317
    [TBL] [Abstract][Full Text] [Related]  

  • 3. STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis.
    Judd LM; Bredin K; Kalantzis A; Jenkins BJ; Ernst M; Giraud AS
    Gastroenterology; 2006 Oct; 131(4):1073-85. PubMed ID: 17030178
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytokine signalling by gp130 regulates gastric mucosal healing after ulceration and, indirectly, antral tumour progression.
    Judd LM; Ulaganathan M; Howlett M; Giraud AS
    J Pathol; 2009 Mar; 217(4):552-62. PubMed ID: 19097069
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of gp130 signaling in breast cancer blocks constitutive activation of Stat3 and inhibits in vivo malignancy.
    Selander KS; Li L; Watson L; Merrell M; Dahmen H; Heinrich PC; Müller-Newen G; Harris KW
    Cancer Res; 2004 Oct; 64(19):6924-33. PubMed ID: 15466183
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state.
    Nishihara M; Ogura H; Ueda N; Tsuruoka M; Kitabayashi C; Tsuji F; Aono H; Ishihara K; Huseby E; Betz UA; Murakami M; Hirano T
    Int Immunol; 2007 Jun; 19(6):695-702. PubMed ID: 17493959
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FR901228, an inhibitor of histone deacetylases, increases the cellular responsiveness to IL-6 type cytokines by enhancing the expression of receptor proteins.
    Blanchard F; Kinzie E; Wang Y; Duplomb L; Godard A; Held WA; Asch BB; Baumann H
    Oncogene; 2002 Sep; 21(41):6264-77. PubMed ID: 12214267
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes.
    Kurth I; Horsten U; Pflanz S; Dahmen H; Küster A; Grötzinger J; Heinrich PC; Müller-Newen G
    J Immunol; 1999 Feb; 162(3):1480-7. PubMed ID: 9973404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Construction of membrane-anchored interleukin-6 receptor beta subunit mutant and its effect on IL-6 signal transduction].
    Yang Z; Ni C; Shen B; Wang J; Wang Z
    Zhonghua Xue Ye Xue Za Zhi; 2000 Dec; 21(12):632-5. PubMed ID: 11877037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.
    Judd LM; Alderman BM; Howlett M; Shulkes A; Dow C; Moverley J; Grail D; Jenkins BJ; Ernst M; Giraud AS
    Gastroenterology; 2004 Jan; 126(1):196-207. PubMed ID: 14699500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.
    Greenhill CJ; Rose-John S; Lissilaa R; Ferlin W; Ernst M; Hertzog PJ; Mansell A; Jenkins BJ
    J Immunol; 2011 Jan; 186(2):1199-208. PubMed ID: 21148800
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases.
    Streetz KL; Tacke F; Leifeld L; Wüstefeld T; Graw A; Klein C; Kamino K; Spengler U; Kreipe H; Kubicka S; Müller W; Manns MP; Trautwein C
    Hepatology; 2003 Jul; 38(1):218-29. PubMed ID: 12830005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IL-6 signal transduction and its physiological roles: the signal orchestration model.
    Kamimura D; Ishihara K; Hirano T
    Rev Physiol Biochem Pharmacol; 2003; 149():1-38. PubMed ID: 12687404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of soluble gp130 released by melanoma cell lines: A polyvalent antagonist of cytokines from the interleukin 6 family.
    Montero-Julian FA; Brailly H; Sautès C; Joyeux I; Dorval T; Mosseri V; Yasukawa K; Wijdenes J; Adler A; Gorin I; Fridman WH; Tartour E
    Clin Cancer Res; 1997 Aug; 3(8):1443-51. PubMed ID: 9815830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation.
    Yamanaka Y; Nakajima K; Fukada T; Hibi M; Hirano T
    EMBO J; 1996 Apr; 15(7):1557-65. PubMed ID: 8612579
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis.
    Nowell MA; Richards PJ; Fielding CA; Ognjanovic S; Topley N; Williams AS; Bryant-Greenwood G; Jones SA
    Arthritis Rheum; 2006 Jul; 54(7):2084-95. PubMed ID: 16802343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Blocking signaling through the Gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumor cells to etoposide and cisplatin-mediated cytotoxicity.
    Borsellino N; Bonavida B; Ciliberto G; Toniatti C; Travali S; D'Alessandro N
    Cancer; 1999 Jan; 85(1):134-44. PubMed ID: 9921985
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells.
    Sawa S; Kamimura D; Jin GH; Morikawa H; Kamon H; Nishihara M; Ishihara K; Murakami M; Hirano T
    J Exp Med; 2006 Jun; 203(6):1459-70. PubMed ID: 16717113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury.
    Klein C; Wüstefeld T; Assmus U; Roskams T; Rose-John S; Müller M; Manns MP; Ernst M; Trautwein C
    J Clin Invest; 2005 Apr; 115(4):860-9. PubMed ID: 15761498
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130).
    Geisterfer M; Richards CD; Gauldie J
    Cytokine; 1995 Aug; 7(6):503-9. PubMed ID: 8580365
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.