351 related articles for article (PubMed ID: 16148027)
1. Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine.
Bar-Am O; Weinreb O; Amit T; Youdim MB
FASEB J; 2005 Nov; 19(13):1899-901. PubMed ID: 16148027
[TBL] [Abstract][Full Text] [Related]
2. Involvement of multiple survival signal transduction pathways in the neuroprotective, neurorescue and APP processing activity of rasagiline and its propargyl moiety.
Weinreb O; Amit T; Bar-Am O; Sagi Y; Mandel S; Youdim MB
J Neural Transm Suppl; 2006; (70):457-65. PubMed ID: 17017568
[TBL] [Abstract][Full Text] [Related]
3. Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway.
Weinreb O; Amit T; Bar-Am O; Chillag-Talmor O; Youdim MB
Ann N Y Acad Sci; 2005 Aug; 1053():348-55. PubMed ID: 16179541
[TBL] [Abstract][Full Text] [Related]
4. A multifunctional, neuroprotective drug, ladostigil (TV3326), regulates holo-APP translation and processing.
Yogev-Falach M; Bar-Am O; Amit T; Weinreb O; Youdim MB
FASEB J; 2006 Oct; 20(12):2177-9. PubMed ID: 16935943
[TBL] [Abstract][Full Text] [Related]
5. Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members.
Weinreb O; Bar-Am O; Amit T; Chillag-Talmor O; Youdim MB
FASEB J; 2004 Sep; 18(12):1471-3. PubMed ID: 15247150
[TBL] [Abstract][Full Text] [Related]
6. The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing.
Yogev-Falach M; Amit T; Bar-Am O; Youdim MB
FASEB J; 2003 Dec; 17(15):2325-7. PubMed ID: 14525944
[TBL] [Abstract][Full Text] [Related]
7. Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease.
Avramovich-Tirosh Y; Amit T; Bar-Am O; Zheng H; Fridkin M; Youdim MB
J Neurochem; 2007 Jan; 100(2):490-502. PubMed ID: 17144902
[TBL] [Abstract][Full Text] [Related]
8. N-Propargylamine protects SH-SY5Y cells from apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, through stabilization of mitochondrial membrane and induction of anti-apoptotic Bcl-2.
Yi H; Maruyama W; Akao Y; Takahashi T; Iwasa K; Youdim MB; Naoi M
J Neural Transm (Vienna); 2006 Jan; 113(1):21-32. PubMed ID: 15843867
[TBL] [Abstract][Full Text] [Related]
9. Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition.
Youdim MB; Bar Am O; Yogev-Falach M; Weinreb O; Maruyama W; Naoi M; Amit T
J Neurosci Res; 2005 Jan 1-15; 79(1-2):172-9. PubMed ID: 15573406
[TBL] [Abstract][Full Text] [Related]
10. Implications of co-morbidity for etiology and treatment of neurodegenerative diseases with multifunctional neuroprotective-neurorescue drugs; ladostigil.
Youdim MB; Amit T; Bar-Am O; Weinreb O; Yogev-Falach M
Neurotox Res; 2006 Dec; 10(3-4):181-92. PubMed ID: 17197368
[TBL] [Abstract][Full Text] [Related]
11. Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate].
Youdim MB; Weinstock M
Cell Mol Neurobiol; 2001 Dec; 21(6):555-73. PubMed ID: 12043833
[TBL] [Abstract][Full Text] [Related]
12. Neuropharmacological, neuroprotective and amyloid precursor processing properties of selective MAO-B inhibitor antiparkinsonian drug, rasagiline.
Youdim MB; Maruyama W; Naoi M
Drugs Today (Barc); 2005 Jun; 41(6):369-91. PubMed ID: 16110345
[TBL] [Abstract][Full Text] [Related]
13. TVP1022 and propargylamine protect neonatal rat ventricular myocytes against doxorubicin-induced and serum starvation-induced cardiotoxicity.
Kleiner Y; Bar-Am O; Amit T; Berdichevski A; Liani E; Maor G; Reiter I; Youdim MB; Binah O
J Cardiovasc Pharmacol; 2008 Sep; 52(3):268-77. PubMed ID: 18806608
[TBL] [Abstract][Full Text] [Related]
14. Differential responses of Bcl-2 family genes to etoposide in chronic myeloid leukemia K562 cells.
Fukumi S; Horiguchi-Yamada J; Nakada S; Nagai M; Ohno T; Yamada H
Mol Cell Biochem; 2000 Mar; 206(1-2):43-50. PubMed ID: 10839193
[TBL] [Abstract][Full Text] [Related]
15. Apoptosis induction in prostate cancer cells and xenografts by combined treatment with Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand and CPT-11.
Ray S; Almasan A
Cancer Res; 2003 Aug; 63(15):4713-23. PubMed ID: 12907654
[TBL] [Abstract][Full Text] [Related]
16. The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline.
Youdim MB; Amit T; Falach-Yogev M; Bar Am O; Maruyama W; Naoi M
Biochem Pharmacol; 2003 Oct; 66(8):1635-41. PubMed ID: 14555244
[TBL] [Abstract][Full Text] [Related]
17. Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.
Woo JH; Kim YH; Choi YJ; Kim DG; Lee KS; Bae JH; Min DS; Chang JS; Jeong YJ; Lee YH; Park JW; Kwon TK
Carcinogenesis; 2003 Jul; 24(7):1199-208. PubMed ID: 12807727
[TBL] [Abstract][Full Text] [Related]
18. Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-alpha, inducible nitric oxide synthase, p53, c-myc, and bax-alpha, and suppression of bcl-2.
Islam N; Haqqi TM; Jepsen KJ; Kraay M; Welter JF; Goldberg VM; Malemud CJ
J Cell Biochem; 2002; 87(3):266-78. PubMed ID: 12397608
[TBL] [Abstract][Full Text] [Related]
19. Induction of Bax and activation of caspases during beta-sitosterol-mediated apoptosis in human colon cancer cells.
Choi YH; Kong KR; Kim YA; Jung KO; Kil JH; Rhee SH; Park KY
Int J Oncol; 2003 Dec; 23(6):1657-62. PubMed ID: 14612938
[TBL] [Abstract][Full Text] [Related]
20. N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor.
Maruyama W; Nitta A; Shamoto-Nagai M; Hirata Y; Akao Y; Yodim M; Furukawa S; Nabeshima T; Naoi M
Neurochem Int; 2004 May; 44(6):393-400. PubMed ID: 14687604
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]