BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 16149069)

  • 1. Optimized transfection of diced siRNA into mature primary human osteoclasts: inhibition of cathepsin K mediated bone resorption by siRNA.
    Selinger CI; Day CJ; Morrison NA
    J Cell Biochem; 2005 Dec; 96(5):996-1002. PubMed ID: 16149069
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts.
    Kneissel M; Luong-Nguyen NH; Baptist M; Cortesi R; Zumstein-Mecker S; Kossida S; O'Reilly T; Lane H; Susa M
    Bone; 2004 Nov; 35(5):1144-56. PubMed ID: 15542040
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of antisense mediated inhibition of cathepsin K on human osteoclasts obtained from peripheral blood.
    Avnet S; Lamolinara A; Zini N; Solimando L; Quacquaruccio G; Granchi D; Maraldi NM; Giunti A; Baldini N
    J Orthop Res; 2006 Aug; 24(8):1699-708. PubMed ID: 16795033
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human osteoclast cathepsin K is processed intracellularly prior to attachment and bone resorption.
    Dodds RA; James IE; Rieman D; Ahern R; Hwang SM; Connor JR; Thompson SD; Veber DF; Drake FH; Holmes S; Lark MW; Gowen M
    J Bone Miner Res; 2001 Mar; 16(3):478-86. PubMed ID: 11277265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice.
    Schurigt U; Hummel KM; Petrow PK; Gajda M; Stöckigt R; Middel P; Zwerina J; Janik T; Bernhardt R; Schüler S; Scharnweber D; Beckmann F; Saftig P; Kollias G; Schett G; Wiederanders B; Bräuer R
    Arthritis Rheum; 2008 Feb; 58(2):422-34. PubMed ID: 18240253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AP-1 stimulates the cathepsin K promoter in RAW 264.7 cells.
    Pang M; Martinez AF; Fernandez I; Balkan W; Troen BR
    Gene; 2007 Nov; 403(1-2):151-8. PubMed ID: 17897792
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro.
    Morko J; Kiviranta R; Mulari MT; Ivaska KK; Väänänen HK; Vuorio E; Laitala-Leinonen T
    Bone; 2009 Apr; 44(4):717-28. PubMed ID: 19118660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis.
    Knowles HJ; Athanasou NA
    J Pathol; 2009 Jun; 218(2):256-64. PubMed ID: 19291710
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Ulmus davidiana Planch (Ulmaceae) on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts.
    Kim KW; Park JS; Kim KS; Jin UH; Kim JK; Suh SJ; Kim CH
    Phytother Res; 2008 Apr; 22(4):511-7. PubMed ID: 18338784
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys.
    Kumar S; Dare L; Vasko-Moser JA; James IE; Blake SM; Rickard DJ; Hwang SM; Tomaszek T; Yamashita DS; Marquis RW; Oh H; Jeong JU; Veber DF; Gowen M; Lark MW; Stroup G
    Bone; 2007 Jan; 40(1):122-31. PubMed ID: 16962401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Different cysteine proteinases involved in bone resorption and osteoclast formation.
    Brage M; Abrahamson M; Lindström V; Grubb A; Lerner UH
    Calcif Tissue Int; 2005 Jun; 76(6):439-47. PubMed ID: 15906014
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cystatin B as an intracellular modulator of bone resorption.
    Laitala-Leinonen T; Rinne R; Saukko P; Väänänen HK; Rinne A
    Matrix Biol; 2006 Apr; 25(3):149-57. PubMed ID: 16321512
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones.
    Xia L; Kilb J; Wex H; Li Z; Lipyansky A; Breuil V; Stein L; Palmer JT; Dempster DW; Brömme D
    Biol Chem; 1999 Jun; 380(6):679-87. PubMed ID: 10430032
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The regulation of cathepsin K gene expression.
    Troen BR
    Ann N Y Acad Sci; 2006 Apr; 1068():165-72. PubMed ID: 16831915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of matrix-degrading cysteine proteinase cathepsin K in cholesteatoma.
    Hansen T; Unger RE; Gaumann A; Hundorf I; Maurer J; Kirkpatrick CJ; Kriegsmann J
    Mod Pathol; 2001 Dec; 14(12):1226-31. PubMed ID: 11743044
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human osteoblasts produce cathepsin K.
    Mandelin J; Hukkanen M; Li TF; Korhonen M; Liljeström M; Sillat T; Hanemaaijer R; Salo J; Santavirta S; Konttinen YT
    Bone; 2006 Jun; 38(6):769-77. PubMed ID: 16337236
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of molecules in mother-of-pearl on the decrease in bone resorption through the inhibition of osteoclast cathepsin K.
    Duplat D; Gallet M; Berland S; Marie A; Dubost L; Rousseau M; Kamel S; Milet C; Brazier M; Lopez E; Bédouet L
    Biomaterials; 2007 Nov; 28(32):4769-78. PubMed ID: 17686515
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Application of small interfering RNA for inhibition of lipopolysaccharide-induced osteoclast formation and cytokine stimulation.
    Fahid FS; Jiang J; Zhu Q; Zhang C; Filbert E; Safavi KE; Spångberg LS
    J Endod; 2008 May; 34(5):563-9. PubMed ID: 18436035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Erosive arthritis in a patient with pycnodysostosis: an experiment of nature.
    Ainola M; Valleala H; Nykänen P; Risteli J; Hanemaaijer R; Konttinen YT
    Arthritis Rheum; 2008 Nov; 58(11):3394-401. PubMed ID: 18975331
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An orally active cathepsin K inhibitor, furan-2-carboxylic acid, 1-{1-[4-fluoro-2-(2-oxo-pyrrolidin-1-yl)-phenyl]-3-oxo-piperidin-4-ylcarbamoyl}-cyclohexyl)-amide (OST-4077), inhibits osteoclast activity in vitro and bone loss in ovariectomized rats.
    Kim MK; Kim HD; Park JH; Lim JI; Yang JS; Kwak WY; Sung SY; Kim HJ; Kim SH; Lee CH; Shim JY; Bae MH; Shin YA; Huh Y; Han TD; Chong W; Choi H; Ahn BN; Yang SO; Son MH
    J Pharmacol Exp Ther; 2006 Aug; 318(2):555-62. PubMed ID: 16699068
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.