354 related articles for article (PubMed ID: 16151804)
1. Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab.
Adams CW; Allison DE; Flagella K; Presta L; Clarke J; Dybdal N; McKeever K; Sliwkowski MX
Cancer Immunol Immunother; 2006 Jun; 55(6):717-27. PubMed ID: 16151804
[TBL] [Abstract][Full Text] [Related]
2. Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Franklin MC; Carey KD; Vajdos FF; Leahy DJ; de Vos AM; Sliwkowski MX
Cancer Cell; 2004 Apr; 5(4):317-28. PubMed ID: 15093539
[TBL] [Abstract][Full Text] [Related]
3. Phase I and pharmacokinetic study of HER2-targeted rhuMAb 2C4 (Pertuzumab, RO4368451) in Japanese patients with solid tumors.
Yamamoto N; Yamada Y; Fujiwara Y; Yamada K; Fujisaka Y; Shimizu T; Tamura T
Jpn J Clin Oncol; 2009 Apr; 39(4):260-6. PubMed ID: 19261664
[TBL] [Abstract][Full Text] [Related]
4. Differential binding patterns of monoclonal antibody 2C4 to the ErbB3-p185her2/neu and the EGFR-p185her2/neu complexes.
Cai Z; Zhang G; Zhou Z; Bembas K; Drebin JA; Greene MI; Zhang H
Oncogene; 2008 Jun; 27(27):3870-4. PubMed ID: 18264138
[TBL] [Abstract][Full Text] [Related]
5. Rationale for a phase II trial of pertuzumab, a HER-2 dimerization inhibitor, in patients with non-small cell lung cancer.
Johnson BE; Jänne PA
Clin Cancer Res; 2006 Jul; 12(14 Pt 2):4436s-4440s. PubMed ID: 16857824
[TBL] [Abstract][Full Text] [Related]
6. Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer.
Agus DB; Gordon MS; Taylor C; Natale RB; Karlan B; Mendelson DS; Press MF; Allison DE; Sliwkowski MX; Lieberman G; Kelsey SM; Fyfe G
J Clin Oncol; 2005 Apr; 23(11):2534-43. PubMed ID: 15699478
[TBL] [Abstract][Full Text] [Related]
7. Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4.
Albanell J; Codony J; Rovira A; Mellado B; Gascón P
Adv Exp Med Biol; 2003; 532():253-68. PubMed ID: 12908564
[TBL] [Abstract][Full Text] [Related]
8. Peptide vaccines of the HER-2/neu dimerization loop are effective in inhibiting mammary tumor growth in vivo.
Allen SD; Garrett JT; Rawale SV; Jones AL; Phillips G; Forni G; Morris JC; Oshima RG; Kaumaya PT
J Immunol; 2007 Jul; 179(1):472-82. PubMed ID: 17579068
[TBL] [Abstract][Full Text] [Related]
9. Hersintuzumab: A novel humanized anti-HER2 monoclonal antibody induces potent tumor growth inhibition.
Amiri MM; Golsaz-Shirazi F; Soltantoyeh T; Hosseini-Ghatar R; Bahadori T; Khoshnoodi J; Navabi SS; Farid S; Karimi-Jafari MH; Jeddi-Tehrani M; Shokri F
Invest New Drugs; 2018 Apr; 36(2):171-186. PubMed ID: 28983766
[TBL] [Abstract][Full Text] [Related]
10. Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status.
Gordon MS; Matei D; Aghajanian C; Matulonis UA; Brewer M; Fleming GF; Hainsworth JD; Garcia AA; Pegram MD; Schilder RJ; Cohn DE; Roman L; Derynck MK; Ng K; Lyons B; Allison DE; Eberhard DA; Pham TQ; Dere RC; Karlan BY
J Clin Oncol; 2006 Sep; 24(26):4324-32. PubMed ID: 16896006
[TBL] [Abstract][Full Text] [Related]
11. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab.
Cho HS; Mason K; Ramyar KX; Stanley AM; Gabelli SB; Denney DW; Leahy DJ
Nature; 2003 Feb; 421(6924):756-60. PubMed ID: 12610629
[TBL] [Abstract][Full Text] [Related]
12. Antitumor activity of the HER2 dimerization inhibitor pertuzumab on human colon cancer cells in vitro and in vivo.
Pohl M; Stricker I; Schoeneck A; Schulmann K; Klein-Scory S; Schwarte-Waldhoff I; Hasmann M; Tannapfel A; Schmiegel W; Reinacher-Schick A
J Cancer Res Clin Oncol; 2009 Oct; 135(10):1377-86. PubMed ID: 19340455
[TBL] [Abstract][Full Text] [Related]
13. In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma.
El-Sahwi K; Bellone S; Cocco E; Cargnelutti M; Casagrande F; Bellone M; Abu-Khalaf M; Buza N; Tavassoli FA; Hui P; Silasi DA; Azodi M; Schwartz PE; Rutherford TJ; Pecorelli S; Santin AD
Br J Cancer; 2010 Jan; 102(1):134-43. PubMed ID: 19920829
[TBL] [Abstract][Full Text] [Related]
14. Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
Ebbing EA; Steins A; Fessler E; Stathi P; Lesterhuis WJ; Krishnadath KK; Vermeulen L; Medema JP; Bijlsma MF; van Laarhoven HWM
Gastroenterology; 2017 Jul; 153(1):63-76.e14. PubMed ID: 28286209
[TBL] [Abstract][Full Text] [Related]
15. Efficacy and safety of single-agent pertuzumab (rhuMAb 2C4), a human epidermal growth factor receptor dimerization inhibitor, in castration-resistant prostate cancer after progression from taxane-based therapy.
Agus DB; Sweeney CJ; Morris MJ; Mendelson DS; McNeel DG; Ahmann FR; Wang J; Derynck MK; Ng K; Lyons B; Allison DE; Kattan MW; Scher HI
J Clin Oncol; 2007 Feb; 25(6):675-81. PubMed ID: 17308272
[TBL] [Abstract][Full Text] [Related]
16. HER-dimerization inhibitors: evaluating pertuzumab in women's cancers.
Kristjansdottir K; Dizon D
Expert Opin Biol Ther; 2010 Feb; 10(2):243-50. PubMed ID: 20001562
[TBL] [Abstract][Full Text] [Related]
17. Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models.
Scheuer W; Friess T; Burtscher H; Bossenmaier B; Endl J; Hasmann M
Cancer Res; 2009 Dec; 69(24):9330-6. PubMed ID: 19934333
[TBL] [Abstract][Full Text] [Related]
18.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
19.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]
