159 related articles for article (PubMed ID: 16153812)
1. Comparison of P-glycoprotein-mediated drug-digoxin interactions in Caco-2 with human and rodent intestine: relevance to in vivo prediction.
Collett A; Tanianis-Hughes J; Carlson GL; Harwood MD; Warhurst G
Eur J Pharm Sci; 2005 Dec; 26(5):386-93. PubMed ID: 16153812
[TBL] [Abstract][Full Text] [Related]
2. The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.
Elsby R; Gillen M; Butters C; Imisson G; Sharma P; Smith V; Surry DD
Drug Metab Dispos; 2011 Feb; 39(2):275-82. PubMed ID: 21075975
[TBL] [Abstract][Full Text] [Related]
3. P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound.
Spahn-Langguth H; Baktir G; Radschuweit A; Okyar A; Terhaag B; Ader P; Hanafy A; Langguth P
Int J Clin Pharmacol Ther; 1998 Jan; 36(1):16-24. PubMed ID: 9476144
[TBL] [Abstract][Full Text] [Related]
4. Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug.
Fenner KS; Troutman MD; Kempshall S; Cook JA; Ware JA; Smith DA; Lee CA
Clin Pharmacol Ther; 2009 Feb; 85(2):173-81. PubMed ID: 18987624
[TBL] [Abstract][Full Text] [Related]
5. Rapid induction of P-glycoprotein expression by high permeability compounds in colonic cells in vitro: a possible source of transporter mediated drug interactions?
Collett A; Tanianis-Hughes J; Warhurst G
Biochem Pharmacol; 2004 Aug; 68(4):783-90. PubMed ID: 15276086
[TBL] [Abstract][Full Text] [Related]
6. In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier.
Hsiao P; Bui T; Ho RJ; Unadkat JD
Drug Metab Dispos; 2008 Mar; 36(3):481-4. PubMed ID: 18057117
[TBL] [Abstract][Full Text] [Related]
7. Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.
Keogh JP; Kunta JR
Eur J Pharm Sci; 2006 Apr; 27(5):543-54. PubMed ID: 16406207
[TBL] [Abstract][Full Text] [Related]
8. Investigation of regional mechanisms responsible for poor oral absorption in humans of a modified release preparation of the alpha-adrenoreceptor antagonist, 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline (UK-338,003): the rational use of ex vivo intestine to predict in vivo absorption.
Collett A; Stephens RH; Harwood MD; Humphrey M; Dallman L; Bennett J; Davis J; Carlson GL; Warhurst G
Drug Metab Dispos; 2008 Jan; 36(1):87-94. PubMed ID: 17932223
[TBL] [Abstract][Full Text] [Related]
9. Echinacea purpurea and P-glycoprotein drug transport in Caco-2 cells.
Hansen TS; Nilsen OG
Phytother Res; 2009 Jan; 23(1):86-91. PubMed ID: 18688789
[TBL] [Abstract][Full Text] [Related]
10. Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein.
Itagaki S; Ochiai A; Kobayashi M; Sugawara M; Hirano T; Iseki K
J Agric Food Chem; 2008 Aug; 56(16):6923-7. PubMed ID: 18656939
[TBL] [Abstract][Full Text] [Related]
11. Effects of diosmin, a flavonoid glycoside in citrus fruits, on P-glycoprotein-mediated drug efflux in human intestinal Caco-2 cells.
Yoo HH; Lee M; Chung HJ; Lee SK; Kim DH
J Agric Food Chem; 2007 Sep; 55(18):7620-5. PubMed ID: 17676865
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of the intestinal digoxin absorption and exsorption by quinidine.
Su SF; Huang JD
Drug Metab Dispos; 1996 Feb; 24(2):142-7. PubMed ID: 8742224
[TBL] [Abstract][Full Text] [Related]
13. Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.
Schinkel AH; Wagenaar E; van Deemter L; Mol CA; Borst P
J Clin Invest; 1995 Oct; 96(4):1698-705. PubMed ID: 7560060
[TBL] [Abstract][Full Text] [Related]
14. Development of a quantitative LC-MS/MS analytical method coupled with turbulent flow chromatography for digoxin for the in vitro P-gp inhibition assay.
Smalley J; Marino AM; Xin B; Olah T; Balimane PV
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jul; 854(1-2):260-7. PubMed ID: 17524973
[TBL] [Abstract][Full Text] [Related]
15. Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells.
Sachs-Barrable K; Thamboo A; Lee SD; Wasan KM
J Pharm Pharm Sci; 2007; 10(3):319-31. PubMed ID: 17727795
[TBL] [Abstract][Full Text] [Related]
16. In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold.
Kishimoto W; Ishiguro N; Ludwig-Schwellinger E; Ebner T; Schaefer O
Drug Metab Dispos; 2014 Feb; 42(2):257-63. PubMed ID: 24212378
[TBL] [Abstract][Full Text] [Related]
17. Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells.
Mertens-Talcott SU; De Castro WV; Manthey JA; Derendorf H; Butterweck V
J Agric Food Chem; 2007 Apr; 55(7):2563-8. PubMed ID: 17348674
[TBL] [Abstract][Full Text] [Related]
18. In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates.
Rautio J; Humphreys JE; Webster LO; Balakrishnan A; Keogh JP; Kunta JR; Serabjit-Singh CJ; Polli JW
Drug Metab Dispos; 2006 May; 34(5):786-92. PubMed ID: 16455806
[TBL] [Abstract][Full Text] [Related]
19. Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney.
Okamura N; Hirai M; Tanigawara Y; Tanaka K; Yasuhara M; Ueda K; Komano T; Hori R
J Pharmacol Exp Ther; 1993 Sep; 266(3):1614-9. PubMed ID: 8103797
[TBL] [Abstract][Full Text] [Related]
20. In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression.
Han Y; Chin Tan TM; Lim LY
Toxicol Appl Pharmacol; 2008 Aug; 230(3):283-9. PubMed ID: 18417181
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]