BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 16153812)

  • 1. Comparison of P-glycoprotein-mediated drug-digoxin interactions in Caco-2 with human and rodent intestine: relevance to in vivo prediction.
    Collett A; Tanianis-Hughes J; Carlson GL; Harwood MD; Warhurst G
    Eur J Pharm Sci; 2005 Dec; 26(5):386-93. PubMed ID: 16153812
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.
    Elsby R; Gillen M; Butters C; Imisson G; Sharma P; Smith V; Surry DD
    Drug Metab Dispos; 2011 Feb; 39(2):275-82. PubMed ID: 21075975
    [TBL] [Abstract][Full Text] [Related]  

  • 3. P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound.
    Spahn-Langguth H; Baktir G; Radschuweit A; Okyar A; Terhaag B; Ader P; Hanafy A; Langguth P
    Int J Clin Pharmacol Ther; 1998 Jan; 36(1):16-24. PubMed ID: 9476144
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug.
    Fenner KS; Troutman MD; Kempshall S; Cook JA; Ware JA; Smith DA; Lee CA
    Clin Pharmacol Ther; 2009 Feb; 85(2):173-81. PubMed ID: 18987624
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rapid induction of P-glycoprotein expression by high permeability compounds in colonic cells in vitro: a possible source of transporter mediated drug interactions?
    Collett A; Tanianis-Hughes J; Warhurst G
    Biochem Pharmacol; 2004 Aug; 68(4):783-90. PubMed ID: 15276086
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier.
    Hsiao P; Bui T; Ho RJ; Unadkat JD
    Drug Metab Dispos; 2008 Mar; 36(3):481-4. PubMed ID: 18057117
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.
    Keogh JP; Kunta JR
    Eur J Pharm Sci; 2006 Apr; 27(5):543-54. PubMed ID: 16406207
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of regional mechanisms responsible for poor oral absorption in humans of a modified release preparation of the alpha-adrenoreceptor antagonist, 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline (UK-338,003): the rational use of ex vivo intestine to predict in vivo absorption.
    Collett A; Stephens RH; Harwood MD; Humphrey M; Dallman L; Bennett J; Davis J; Carlson GL; Warhurst G
    Drug Metab Dispos; 2008 Jan; 36(1):87-94. PubMed ID: 17932223
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Echinacea purpurea and P-glycoprotein drug transport in Caco-2 cells.
    Hansen TS; Nilsen OG
    Phytother Res; 2009 Jan; 23(1):86-91. PubMed ID: 18688789
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein.
    Itagaki S; Ochiai A; Kobayashi M; Sugawara M; Hirano T; Iseki K
    J Agric Food Chem; 2008 Aug; 56(16):6923-7. PubMed ID: 18656939
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of diosmin, a flavonoid glycoside in citrus fruits, on P-glycoprotein-mediated drug efflux in human intestinal Caco-2 cells.
    Yoo HH; Lee M; Chung HJ; Lee SK; Kim DH
    J Agric Food Chem; 2007 Sep; 55(18):7620-5. PubMed ID: 17676865
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of the intestinal digoxin absorption and exsorption by quinidine.
    Su SF; Huang JD
    Drug Metab Dispos; 1996 Feb; 24(2):142-7. PubMed ID: 8742224
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.
    Schinkel AH; Wagenaar E; van Deemter L; Mol CA; Borst P
    J Clin Invest; 1995 Oct; 96(4):1698-705. PubMed ID: 7560060
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of a quantitative LC-MS/MS analytical method coupled with turbulent flow chromatography for digoxin for the in vitro P-gp inhibition assay.
    Smalley J; Marino AM; Xin B; Olah T; Balimane PV
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jul; 854(1-2):260-7. PubMed ID: 17524973
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells.
    Sachs-Barrable K; Thamboo A; Lee SD; Wasan KM
    J Pharm Pharm Sci; 2007; 10(3):319-31. PubMed ID: 17727795
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold.
    Kishimoto W; Ishiguro N; Ludwig-Schwellinger E; Ebner T; Schaefer O
    Drug Metab Dispos; 2014 Feb; 42(2):257-63. PubMed ID: 24212378
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells.
    Mertens-Talcott SU; De Castro WV; Manthey JA; Derendorf H; Butterweck V
    J Agric Food Chem; 2007 Apr; 55(7):2563-8. PubMed ID: 17348674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates.
    Rautio J; Humphreys JE; Webster LO; Balakrishnan A; Keogh JP; Kunta JR; Serabjit-Singh CJ; Polli JW
    Drug Metab Dispos; 2006 May; 34(5):786-92. PubMed ID: 16455806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney.
    Okamura N; Hirai M; Tanigawara Y; Tanaka K; Yasuhara M; Ueda K; Komano T; Hori R
    J Pharmacol Exp Ther; 1993 Sep; 266(3):1614-9. PubMed ID: 8103797
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression.
    Han Y; Chin Tan TM; Lim LY
    Toxicol Appl Pharmacol; 2008 Aug; 230(3):283-9. PubMed ID: 18417181
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.