151 related articles for article (PubMed ID: 16159134)
1. Identification and characterization of deamidation sites in the conserved regions of human immunoglobulin gamma antibodies.
Chelius D; Rehder DS; Bondarenko PV
Anal Chem; 2005 Sep; 77(18):6004-11. PubMed ID: 16159134
[TBL] [Abstract][Full Text] [Related]
2. Atypical Asparagine Deamidation of NW Motif Significantly Attenuates the Biological Activities of an Antibody Drug Conjugate.
Cao M; Hussmann GP; Tao Y; O'Connor E; Parthemore C; Zhang-Hulsey D; Liu D; Jiao Y; Mel N; Prophet M; Korman S; Sonawane J; Grigoriadou C; Huang Y; Umlauf S; Chen X
Antibodies (Basel); 2023 Oct; 12(4):. PubMed ID: 37987246
[TBL] [Abstract][Full Text] [Related]
3. Multiplex Bioanalytical Methods for Comprehensive Characterization and Quantification of the Unique Complementarity-Determining-Region Deamidation of MEDI7247, an Anti-ASCT2 Pyrrolobenzodiazepine Antibody-Drug Conjugate.
Huang Y; Yuan J; Mu R; Kubiak RJ; Ball K; Cao M; Hussmann GP; de Mel N; Liu D; Roskos LK; Liang M; Rosenbaum AI
Antibodies (Basel); 2023 Oct; 12(4):. PubMed ID: 37873863
[TBL] [Abstract][Full Text] [Related]
4. Isoaspartate and neurodegeneration.
Wang J; Mukherjee S; Zubarev RA
Aging (Albany NY); 2022 Nov; 14(22):8882-8883. PubMed ID: 36446387
[No Abstract] [Full Text] [Related]
5. Translatability of
Chu PY; Wang H; Ross E; Stephens N; Zhang HM; Andersen N; Chan W; Shivva V; Crowell SR; Spiess C; Holder PG; Agard NJ; Ji C; Chen J; Sreedhara A; Wang J; Wu C; Liu Y; Tran JC
Anal Chem; 2023 Dec; 95(49):17957-17961. PubMed ID: 38084380
[TBL] [Abstract][Full Text] [Related]
6. Asparagine deamidation dependence on buffer type, pH, and temperature.
Pace AL; Wong RL; Zhang YT; Kao YH; Wang YJ
J Pharm Sci; 2013 Jun; 102(6):1712-1723. PubMed ID: 23568760
[TBL] [Abstract][Full Text] [Related]
7. Formulation considerations for proteins susceptible to asparagine deamidation and aspartate isomerization.
Wakankar AA; Borchardt RT
J Pharm Sci; 2006 Nov; 95(11):2321-36. PubMed ID: 16960822
[TBL] [Abstract][Full Text] [Related]
8. Identification and characterization of oxidation and deamidation sites in monoclonal rat/mouse hybrid antibodies.
Timm V; Gruber P; Wasiliu M; Lindhofer H; Chelius D
J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Mar; 878(9-10):777-84. PubMed ID: 20153988
[TBL] [Abstract][Full Text] [Related]
9. Identification of deamidation and isomerization sites on pharmaceutical recombinant antibody using H(2)(18)O.
Terashima I; Koga A; Nagai H
Anal Biochem; 2007 Sep; 368(1):49-60. PubMed ID: 17617368
[TBL] [Abstract][Full Text] [Related]
10. Heterogeneity of monoclonal antibodies.
Liu H; Gaza-Bulseco G; Faldu D; Chumsae C; Sun J
J Pharm Sci; 2008 Jul; 97(7):2426-47. PubMed ID: 17828757
[TBL] [Abstract][Full Text] [Related]
11. Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions.
Sydow JF; Lipsmeier F; Larraillet V; Hilger M; Mautz B; Mølhøj M; Kuentzer J; Klostermann S; Schoch J; Voelger HR; Regula JT; Cramer P; Papadimitriou A; Kettenberger H
PLoS One; 2014; 9(6):e100736. PubMed ID: 24959685
[TBL] [Abstract][Full Text] [Related]
12. Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody.
Vlasak J; Bussat MC; Wang S; Wagner-Rousset E; Schaefer M; Klinguer-Hamour C; Kirchmeier M; Corvaïa N; Ionescu R; Beck A
Anal Biochem; 2009 Sep; 392(2):145-54. PubMed ID: 19497295
[TBL] [Abstract][Full Text] [Related]
13. Effect of methionine oxidation of a recombinant monoclonal antibody on the binding affinity to protein A and protein G.
Gaza-Bulseco G; Faldu S; Hurkmans K; Chumsae C; Liu H
J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Jul; 870(1):55-62. PubMed ID: 18567545
[TBL] [Abstract][Full Text] [Related]
14. Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies.
Wang W; Vlasak J; Li Y; Pristatsky P; Fang Y; Pittman T; Roman J; Wang Y; Prueksaritanont T; Ionescu R
Mol Immunol; 2011 Mar; 48(6-7):860-6. PubMed ID: 21256596
[TBL] [Abstract][Full Text] [Related]
15. Rate of Asparagine Deamidation in a Monoclonal Antibody Correlating with Hydrogen Exchange Rate at Adjacent Downstream Residues.
Phillips JJ; Buchanan A; Andrews J; Chodorge M; Sridharan S; Mitchell L; Burmeister N; Kippen AD; Vaughan TJ; Higazi DR; Lowe D
Anal Chem; 2017 Feb; 89(4):2361-2368. PubMed ID: 28194941
[TBL] [Abstract][Full Text] [Related]
16. Characterization of asparagine 330 deamidation in an Fc-fragment of IgG1 using cation exchange chromatography and peptide mapping.
Zhang YT; Hu J; Pace AL; Wong R; Wang YJ; Kao YH
J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Aug; 965():65-71. PubMed ID: 24999246
[TBL] [Abstract][Full Text] [Related]
17. Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody.
Sinha S; Zhang L; Duan S; Williams TD; Vlasak J; Ionescu R; Topp EM
Protein Sci; 2009 Aug; 18(8):1573-84. PubMed ID: 19544580
[TBL] [Abstract][Full Text] [Related]
18. Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.
Yan B; Steen S; Hambly D; Valliere-Douglass J; Vanden Bos T; Smallwood S; Yates Z; Arroll T; Han Y; Gadgil H; Latypov RF; Wallace A; Lim A; Kleemann GR; Wang W; Balland A
J Pharm Sci; 2009 Oct; 98(10):3509-21. PubMed ID: 19475547
[TBL] [Abstract][Full Text] [Related]
19. Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures.
Diepold K; Bomans K; Wiedmann M; Zimmermann B; Petzold A; Schlothauer T; Mueller R; Moritz B; Stracke JO; Mølhøj M; Reusch D; Bulau P
PLoS One; 2012; 7(1):e30295. PubMed ID: 22272329
[TBL] [Abstract][Full Text] [Related]
20. Glutamine deamidation of a recombinant monoclonal antibody.
Liu H; Gaza-Bulseco G; Chumsae C
Rapid Commun Mass Spectrom; 2008 Dec; 22(24):4081-8. PubMed ID: 19021137
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
