151 related articles for article (PubMed ID: 16159134)
21. Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods.
Vlasak J; Ionescu R
Curr Pharm Biotechnol; 2008 Dec; 9(6):468-81. PubMed ID: 19075686
[TBL] [Abstract][Full Text] [Related]
22. Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats.
Khawli LA; Goswami S; Hutchinson R; Kwong ZW; Yang J; Wang X; Yao Z; Sreedhara A; Cano T; Tesar D; Nijem I; Allison DE; Wong PY; Kao YH; Quan C; Joshi A; Harris RJ; Motchnik P
MAbs; 2010; 2(6):613-24. PubMed ID: 20818176
[TBL] [Abstract][Full Text] [Related]
23. Antibody glycosylation and its impact on the pharmacokinetics and pharmacodynamics of monoclonal antibodies and Fc-fusion proteins.
Liu L
J Pharm Sci; 2015 Jun; 104(6):1866-1884. PubMed ID: 25872915
[TBL] [Abstract][Full Text] [Related]
24. Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.
Geiger T; Clarke S
J Biol Chem; 1987 Jan; 262(2):785-94. PubMed ID: 3805008
[TBL] [Abstract][Full Text] [Related]
25. Rates and impact of human antibody glycation in vivo.
Goetze AM; Liu YD; Arroll T; Chu L; Flynn GC
Glycobiology; 2012 Feb; 22(2):221-34. PubMed ID: 21930650
[TBL] [Abstract][Full Text] [Related]
26. Effects of amino acid sequence, buffers, and ionic strength on the rate and mechanism of deamidation of asparagine residues in small peptides.
Tyler-Cross R; Schirch V
J Biol Chem; 1991 Nov; 266(33):22549-56. PubMed ID: 1939272
[TBL] [Abstract][Full Text] [Related]
27. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
Yang L; Chang CC; Sun Z; Madsen D; Zhu H; Padkjær SB; Wu X; Huang T; Hultman K; Paulsen SJ; Wang J; Bugge A; Frantzen JB; Nørgaard P; Jeppesen JF; Yang Z; Secher A; Chen H; Li X; John LM; Shan B; He Z; Gao X; Su J; Hansen KT; Yang W; Jørgensen SB
Nat Med; 2017 Oct; 23(10):1158-1166. PubMed ID: 28846099
[TBL] [Abstract][Full Text] [Related]
28. Chromatographic analysis of the acidic and basic species of recombinant monoclonal antibodies.
Du Y; Walsh A; Ehrick R; Xu W; May K; Liu H
MAbs; 2012; 4(5):578-85. PubMed ID: 22820257
[TBL] [Abstract][Full Text] [Related]
29. Methionine, tryptophan, and histidine oxidation in a model protein, PTH: mechanisms and stabilization.
Ji JA; Zhang B; Cheng W; Wang YJ
J Pharm Sci; 2009 Dec; 98(12):4485-500. PubMed ID: 19455640
[TBL] [Abstract][Full Text] [Related]
30. Disulfide bond structures of IgG molecules: structural variations, chemical modifications and possible impacts to stability and biological function.
Liu H; May K
MAbs; 2012; 4(1):17-23. PubMed ID: 22327427
[TBL] [Abstract][Full Text] [Related]
31. Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides.
Yang H; Zubarev RA
Electrophoresis; 2010 Jun; 31(11):1764-72. PubMed ID: 20446295
[TBL] [Abstract][Full Text] [Related]
32. Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-Orbitrap mass spectrometer.
Bondarenko PV; Second TP; Zabrouskov V; Makarov AA; Zhang Z
J Am Soc Mass Spectrom; 2009 Aug; 20(8):1415-24. PubMed ID: 19409810
[TBL] [Abstract][Full Text] [Related]
33. Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn.
Pan H; Chen K; Chu L; Kinderman F; Apostol I; Huang G
Protein Sci; 2009 Feb; 18(2):424-33. PubMed ID: 19165723
[TBL] [Abstract][Full Text] [Related]
34. Characterization of variable regions of monoclonal antibodies by top-down mass spectrometry.
Zhang Z; Shah B
Anal Chem; 2007 Aug; 79(15):5723-9. PubMed ID: 17591752
[TBL] [Abstract][Full Text] [Related]
35. Antibody structure, instability, and formulation.
Wang W; Singh S; Zeng DL; King K; Nema S
J Pharm Sci; 2007 Jan; 96(1):1-26. PubMed ID: 16998873
[TBL] [Abstract][Full Text] [Related]
36. Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature.
Liu H; Gaza-Bulseco G; Sun J
J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Jun; 837(1-2):35-43. PubMed ID: 16644295
[TBL] [Abstract][Full Text] [Related]
37. Monoclonal antibody heterogeneity analysis and deamidation monitoring with high-performance cation-exchange chromatofocusing using simple, two component buffer systems.
Kang X; Kutzko JP; Hayes ML; Frey DD
J Chromatogr A; 2013 Mar; 1283():89-97. PubMed ID: 23428023
[TBL] [Abstract][Full Text] [Related]
38. A study in glycation of a therapeutic recombinant humanized monoclonal antibody: where it is, how it got there, and how it affects charge-based behavior.
Quan C; Alcala E; Petkovska I; Matthews D; Canova-Davis E; Taticek R; Ma S
Anal Biochem; 2008 Feb; 373(2):179-91. PubMed ID: 18158144
[TBL] [Abstract][Full Text] [Related]
39. Understanding the conformational impact of chemical modifications on monoclonal antibodies with diverse sequence variation using hydrogen/deuterium exchange mass spectrometry and structural modeling.
Zhang A; Hu P; MacGregor P; Xue Y; Fan H; Suchecki P; Olszewski L; Liu A
Anal Chem; 2014 Apr; 86(7):3468-75. PubMed ID: 24597564
[TBL] [Abstract][Full Text] [Related]
40. Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes.
Haberger M; Bomans K; Diepold K; Hook M; Gassner J; Schlothauer T; Zwick A; Spick C; Kepert JF; Hienz B; Wiedmann M; Beck H; Metzger P; Mølhøj M; Knoblich C; Grauschopf U; Reusch D; Bulau P
MAbs; 2014; 6(2):327-39. PubMed ID: 24441081
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
