These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 16159876)

  • 1. Structural details on mdm2-p53 interaction.
    Chi SW; Lee SH; Kim DH; Ahn MJ; Kim JS; Woo JY; Torizawa T; Kainosho M; Han KH
    J Biol Chem; 2005 Nov; 280(46):38795-802. PubMed ID: 16159876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determinants of specificity of MDM2 for the activation domains of p53 and p65: proline27 disrupts the MDM2-binding motif of p53.
    Zondlo SC; Lee AE; Zondlo NJ
    Biochemistry; 2006 Oct; 45(39):11945-57. PubMed ID: 17002294
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
    Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
    Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
    Kussie PH; Gorina S; Marechal V; Elenbaas B; Moreau J; Levine AJ; Pavletich NP
    Science; 1996 Nov; 274(5289):948-53. PubMed ID: 8875929
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo.
    Shimizu H; Burch LR; Smith AJ; Dornan D; Wallace M; Ball KL; Hupp TR
    J Biol Chem; 2002 Aug; 277(32):28446-58. PubMed ID: 11925449
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular recognition of p53 and MDM2 by USP7/HAUSP.
    Sheng Y; Saridakis V; Sarkari F; Duan S; Wu T; Arrowsmith CH; Frappier L
    Nat Struct Mol Biol; 2006 Mar; 13(3):285-91. PubMed ID: 16474402
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition.
    Shin JS; Ha JH; Lee DH; Ryu KS; Bae KH; Park BC; Park SG; Yi GS; Chi SW
    Cell Cycle; 2015; 14(4):533-43. PubMed ID: 25591003
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting of p53 peptide analogues to anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy.
    Shin JS; Ha JH; Chi SW
    Biochem Biophys Res Commun; 2014 Jan; 443(3):882-7. PubMed ID: 24342622
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphomimetic mutation of the N-terminal lid of MDM2 enhances the polyubiquitination of p53 through stimulation of E2-ubiquitin thioester hydrolysis.
    Fraser JA; Worrall EG; Lin Y; Landre V; Pettersson S; Blackburn E; Walkinshaw M; Muller P; Vojtesek B; Ball K; Hupp TR
    J Mol Biol; 2015 Apr; 427(8):1728-47. PubMed ID: 25543083
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The MDM2-binding region in the transactivation domain of p53 also acts as a Bcl-X(L)-binding motif.
    Xu H; Ye H; Osman NE; Sadler K; Won EY; Chi SW; Yoon HS
    Biochemistry; 2009 Dec; 48(51):12159-68. PubMed ID: 19916559
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binding induced folding in p53-MDM2 complex.
    Chen HF; Luo R
    J Am Chem Soc; 2007 Mar; 129(10):2930-7. PubMed ID: 17302414
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Competitive binding between dynamic p53 transactivation subdomains to human MDM2 protein: implications for regulating the p53·MDM2/MDMX interaction.
    Shan B; Li DW; Brüschweiler-Li L; Brüschweiler R
    J Biol Chem; 2012 Aug; 287(36):30376-84. PubMed ID: 22807444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Mechanism of p53 Rescue by SUSP4.
    Kim DH; Lee C; Lee SH; Kim KT; Han JJ; Cha EJ; Lim JE; Cho YJ; Hong SH; Han KH
    Angew Chem Int Ed Engl; 2017 Jan; 56(5):1278-1282. PubMed ID: 28000315
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rescuing p53 from mdm2 by a pre-structured motif in intrinsically unfolded SUMO specific protease 4.
    Kim DH; Lee C; Kim B; Lee SH; Han KH
    BMB Rep; 2017 Oct; 50(10):485-486. PubMed ID: 28712389
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2.
    Yadahalli S; Neira JL; Johnson CM; Tan YS; Rowling PJE; Chattopadhyay A; Verma CS; Itzhaki LS
    Sci Rep; 2019 Jan; 9(1):693. PubMed ID: 30679555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bridging Microscopic and Macroscopic Mechanisms of p53-MDM2 Binding with Kinetic Network Models.
    Zhou G; Pantelopulos GA; Mukherjee S; Voelz VA
    Biophys J; 2017 Aug; 113(4):785-793. PubMed ID: 28834715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2.
    Ferreon JC; Lee CW; Arai M; Martinez-Yamout MA; Dyson HJ; Wright PE
    Proc Natl Acad Sci U S A; 2009 Apr; 106(16):6591-6. PubMed ID: 19357310
    [TBL] [Abstract][Full Text] [Related]  

  • 18. C-terminal substitution of MDM2 interacting peptides modulates binding affinity by distinctive mechanisms.
    Brown CJ; Dastidar SG; Quah ST; Lim A; Chia B; Verma CS
    PLoS One; 2011; 6(8):e24122. PubMed ID: 21904608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2.
    Uesugi M; Verdine GL
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14801-6. PubMed ID: 10611293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. S100 proteins interact with the N-terminal domain of MDM2.
    van Dieck J; Lum JK; Teufel DP; Fersht AR
    FEBS Lett; 2010 Aug; 584(15):3269-74. PubMed ID: 20591429
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.