112 related articles for article (PubMed ID: 16162941)
1. Peroxisome proliferator-activated receptor alpha controls cellular cholesterol trafficking in macrophages.
Chinetti-Gbaguidi G; Rigamonti E; Helin L; Mutka AL; Lepore M; Fruchart JC; Clavey V; Ikonen E; Lestavel S; Staels B
J Lipid Res; 2005 Dec; 46(12):2717-25. PubMed ID: 16162941
[TBL] [Abstract][Full Text] [Related]
2. OxLDL up-regulates Niemann-Pick type C1 expression through ERK1/2/COX-2/PPARα-signaling pathway in macrophages.
Yu X; Li X; Zhao G; Xiao J; Mo Z; Yin K; Jiang Z; Fu Y; Zha X; Tang C
Acta Biochim Biophys Sin (Shanghai); 2012 Feb; 44(2):119-28. PubMed ID: 22232299
[TBL] [Abstract][Full Text] [Related]
3. Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages.
Rigamonti E; Helin L; Lestavel S; Mutka AL; Lepore M; Fontaine C; Bouhlel MA; Bultel S; Fruchart JC; Ikonen E; Clavey V; Staels B; Chinetti-Gbaguidi G
Circ Res; 2005 Sep; 97(7):682-9. PubMed ID: 16141411
[TBL] [Abstract][Full Text] [Related]
4. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
Boadu E; Nelson RC; Francis GA
Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
[TBL] [Abstract][Full Text] [Related]
5. NPC1, intracellular cholesterol trafficking and atherosclerosis.
Yu XH; Jiang N; Yao PB; Zheng XL; Cayabyab FS; Tang CK
Clin Chim Acta; 2014 Feb; 429():69-75. PubMed ID: 24296264
[TBL] [Abstract][Full Text] [Related]
6. Peroxisome proliferator-activated receptor alpha reduces cholesterol esterification in macrophages.
Chinetti G; Lestavel S; Fruchart JC; Clavey V; Staels B
Circ Res; 2003 Feb; 92(2):212-7. PubMed ID: 12574149
[TBL] [Abstract][Full Text] [Related]
7. Alpinetin enhances cholesterol efflux and inhibits lipid accumulation in oxidized low-density lipoprotein-loaded human macrophages.
Jiang Z; Sang H; Fu X; Liang Y; Li L
Biotechnol Appl Biochem; 2015; 62(6):840-7. PubMed ID: 25496323
[TBL] [Abstract][Full Text] [Related]
8. Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype.
Taylor JM; Allen AM; Graham A
Clin Sci (Lond); 2014 Nov; 127(10):603-13. PubMed ID: 24814875
[TBL] [Abstract][Full Text] [Related]
9. Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
Babaev VR; Ishiguro H; Ding L; Yancey PG; Dove DE; Kovacs WJ; Semenkovich CF; Fazio S; Linton MF
Circulation; 2007 Sep; 116(12):1404-12. PubMed ID: 17724261
[TBL] [Abstract][Full Text] [Related]
10. Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.
Taketa K; Matsumura T; Yano M; Ishii N; Senokuchi T; Motoshima H; Murata Y; Kim-Mitsuyama S; Kawada T; Itabe H; Takeya M; Nishikawa T; Tsuruzoe K; Araki E
J Biol Chem; 2008 Apr; 283(15):9852-62. PubMed ID: 18208815
[TBL] [Abstract][Full Text] [Related]
11. NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.
Frolov A; Zielinski SE; Crowley JR; Dudley-Rucker N; Schaffer JE; Ory DS
J Biol Chem; 2003 Jul; 278(28):25517-25. PubMed ID: 12719428
[TBL] [Abstract][Full Text] [Related]
12. Downregulated CD36 and oxLDL uptake and stimulated ABCA1/G1 and cholesterol efflux as anti-atherosclerotic mechanisms of interleukin-10.
Rubic T; Lorenz RL
Cardiovasc Res; 2006 Feb; 69(2):527-35. PubMed ID: 16336952
[TBL] [Abstract][Full Text] [Related]
13. Emodin enhances cholesterol efflux by activating peroxisome proliferator-activated receptor-γ in oxidized low density lipoprotein-loaded THP1 macrophages.
Fu X; Xu AG; Yao MY; Guo L; Zhao LS
Clin Exp Pharmacol Physiol; 2014 Sep; 41(9):679-84. PubMed ID: 24837536
[TBL] [Abstract][Full Text] [Related]
14. NPC1-containing compartment of human granulosa-lutein cells: a role in the intracellular trafficking of cholesterol supporting steroidogenesis.
Watari H; Blanchette-Mackie EJ; Dwyer NK; Sun G; Glick JM; Patel S; Neufeld EB; Pentchev PG; Strauss JF
Exp Cell Res; 2000 Feb; 255(1):56-66. PubMed ID: 10666334
[TBL] [Abstract][Full Text] [Related]
15. Physiological and coordinate downregulation of the NPC1 and NPC2 genes are associated with the sequestration of LDL-derived cholesterol within endocytic compartments.
Jelinek D; Patrick SM; Kitt KN; Chan T; Francis GA; Garver WS
J Cell Biochem; 2009 Dec; 108(5):1102-16. PubMed ID: 19746448
[TBL] [Abstract][Full Text] [Related]
16. ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.
Feng B; Tabas I
J Biol Chem; 2002 Nov; 277(45):43271-80. PubMed ID: 12215451
[TBL] [Abstract][Full Text] [Related]
17. Niemann-Pick type C disease: a QM/MM study of conformational changes in cholesterol in the NPC1(NTD) and NPC2 binding pockets.
Elghobashi-Meinhardt N
Biochemistry; 2014 Oct; 53(41):6603-14. PubMed ID: 25251378
[TBL] [Abstract][Full Text] [Related]
18. The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.
Hennuyer N; Duplan I; Paquet C; Vanhoutte J; Woitrain E; Touche V; Colin S; Vallez E; Lestavel S; Lefebvre P; Staels B
Atherosclerosis; 2016 Jun; 249():200-8. PubMed ID: 27108950
[TBL] [Abstract][Full Text] [Related]
19. The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking.
Liao Y; Wei J; Wang J; Shi X; Luo J; Song BL
Sci China Life Sci; 2018 Oct; 61(10):1222-1232. PubMed ID: 30091016
[TBL] [Abstract][Full Text] [Related]
20. Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.
Frolov A; Srivastava K; Daphna-Iken D; Traub LM; Schaffer JE; Ory DS
J Biol Chem; 2001 Dec; 276(49):46414-21. PubMed ID: 11571306
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
