BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 16165365)

  • 1. Enantioselective synthesis of 1-methoxy- and 1-deoxy-2'-methyl-delta8-tetrahydrocannabinols: new selective ligands for the CB2 receptor.
    Huffman JW; Bushell SM; Joshi SN; Wiley JL; Martin BR
    Bioorg Med Chem; 2006 Jan; 14(1):247-62. PubMed ID: 16165365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and pharmacology of 11-nor-1-methoxy-9-hydroxyhexahydrocannabinols and 11-nor-1-deoxy-9-hydroxyhexahydrocannabinols: new selective ligands for the cannabinoid CB2 receptor.
    Marriott KS; Huffman JW; Wiley JL; Martin BR
    Bioorg Med Chem; 2006 Apr; 14(7):2386-97. PubMed ID: 16321538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor.
    Huffman JW; Liddle J; Yu S; Aung MM; Abood ME; Wiley JL; Martin BR
    Bioorg Med Chem; 1999 Dec; 7(12):2905-14. PubMed ID: 10658595
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The search for selective ligands for the CB2 receptor.
    Huffman JW
    Curr Pharm Des; 2000 Sep; 6(13):1323-37. PubMed ID: 10903395
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols.
    Papahatjis DP; Kourouli T; Abadji V; Goutopoulos A; Makriyannis A
    J Med Chem; 1998 Mar; 41(7):1195-200. PubMed ID: 9544219
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors.
    Huffman JW; Padgett LW; Isherwood ML; Wiley JL; Martin BR
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5432-5. PubMed ID: 16889960
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs.
    Krishnamurthy M; Gurley S; Moore BM
    Bioorg Med Chem; 2008 Jul; 16(13):6489-500. PubMed ID: 18524604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The application of 3D-QSAR studies for novel cannabinoid ligands substituted at the C1' position of the alkyl side chain on the structural requirements for binding to cannabinoid receptors CB1 and CB2.
    Durdagi S; Kapou A; Kourouli T; Andreou T; Nikas SP; Nahmias VR; Papahatjis DP; Papadopoulos MG; Mavromoustakos T
    J Med Chem; 2007 Jun; 50(12):2875-85. PubMed ID: 17521177
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural modifications of the cannabinoid side chain towards C3-aryl and 1',1'-cycloalkyl-1'-cyano cannabinoids.
    Papahatjis DP; Nahmias VR; Andreou T; Fan P; Makriyannis A
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1616-20. PubMed ID: 16387492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1'.
    Papahatjis DP; Nikas SP; Kourouli T; Chari R; Xu W; Pertwee RG; Makriyannis A
    J Med Chem; 2003 Jul; 46(15):3221-9. PubMed ID: 12852753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor.
    Marriott KS; Huffman JW
    Curr Top Med Chem; 2008; 8(3):187-204. PubMed ID: 18289088
    [TBL] [Abstract][Full Text] [Related]  

  • 12. C1'-cycloalkyl side chain pharmacophore in tetrahydrocannabinols.
    Papahatjis DP; Nahmias VR; Nikas SP; Andreou T; Alapafuja SO; Tsotinis A; Guo J; Fan P; Makriyannis A
    J Med Chem; 2007 Aug; 50(17):4048-60. PubMed ID: 17672444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles.
    Huffman JW; Szklennik PV; Almond A; Bushell K; Selley DE; He H; Cassidy MP; Wiley JL; Martin BR
    Bioorg Med Chem Lett; 2005 Sep; 15(18):4110-3. PubMed ID: 16005223
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cannabinoid-mediated elevation of intracellular calcium: a structure-activity relationship.
    Rao GK; Kaminski NE
    J Pharmacol Exp Ther; 2006 May; 317(2):820-9. PubMed ID: 16436496
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcriptional regulation of the cannabinoid receptor type 1 gene in T cells by cannabinoids.
    Börner C; Höllt V; Sebald W; Kraus J
    J Leukoc Biol; 2007 Jan; 81(1):336-43. PubMed ID: 17041005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of (+)-(1'R,2'S) and (1'S,2'R)-6,11-dimethyl-1,2,3,4,5,6 -hexahydro-3-[[2'-(alkoxycarbonyl)-2'-phenylcyclopropyl]methyl]-2 ,6 -methano-3-benzazocin-8-ol. Comparison of the affinities for sigma 1 and opioid receptors with in the diastereoisomeric MPCB and CCB.
    Ronsisvalle G; Prezzavento O; Pasquinucci L; Pappalardo MS; Marrazzo A; Vittorio F; Carboni L; Spampinato S
    Farmaco; 1997; 52(6-7):471-6. PubMed ID: 9372600
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Delta(8)-tetrahydrocannabinols: new selective ligands for the CB2 receptor.
    Huffman JW; Bushell SM; Miller JR; Wiley JL; Martin BR
    Bioorg Med Chem; 2002 Dec; 10(12):4119-29. PubMed ID: 12413866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of CoMFA and CoMSIA models of affinity and selectivity for indole ligands of cannabinoid CB1 and CB2 receptors.
    De Freitas GB; da Silva LL; Romeiro NC; Fraga CA
    Eur J Med Chem; 2009 Jun; 44(6):2482-96. PubMed ID: 19249138
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent cyano and carboxamido side-chain analogues of 1', 1'-dimethyl-delta8-tetrahydrocannabinol.
    Singer M; Ryan WJ; Saha B; Martin BR; Razdan RK
    J Med Chem; 1998 Oct; 41(22):4400-7. PubMed ID: 9784115
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 6-Methoxy-N-alkyl isatin acylhydrazone derivatives as a novel series of potent selective cannabinoid receptor 2 inverse agonists: design, synthesis, and binding mode prediction.
    Diaz P; Phatak SS; Xu J; Astruc-Diaz F; Cavasotto CN; Naguib M
    J Med Chem; 2009 Jan; 52(2):433-44. PubMed ID: 19115816
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.