BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 16169901)

  • 21. AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3.
    Ahmad K; Scholz B; Capelo R; Schweighöfer I; Kahnt AS; Marschalek R; Steinhilber D
    Oncotarget; 2015 Sep; 6(28):25784-800. PubMed ID: 26329759
    [TBL] [Abstract][Full Text] [Related]  

  • 22. H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
    Krivtsov AV; Feng Z; Lemieux ME; Faber J; Vempati S; Sinha AU; Xia X; Jesneck J; Bracken AP; Silverman LB; Kutok JL; Kung AL; Armstrong SA
    Cancer Cell; 2008 Nov; 14(5):355-68. PubMed ID: 18977325
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
    Dawson MA; Prinjha RK; Dittmann A; Giotopoulos G; Bantscheff M; Chan WI; Robson SC; Chung CW; Hopf C; Savitski MM; Huthmacher C; Gudgin E; Lugo D; Beinke S; Chapman TD; Roberts EJ; Soden PE; Auger KR; Mirguet O; Doehner K; Delwel R; Burnett AK; Jeffrey P; Drewes G; Lee K; Huntly BJ; Kouzarides T
    Nature; 2011 Oct; 478(7370):529-33. PubMed ID: 21964340
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.
    van der Linden MH; Seslija L; Schneider P; Driessen EM; Castro PG; Stumpel DJ; van Roon E; de Boer J; Williams O; Pieters R; Stam RW
    PLoS One; 2015; 10(3):e0120326. PubMed ID: 25793396
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Restoring MLL reactivates latent tumor suppression-mediated vulnerability to proteasome inhibitors.
    Ge M; Li D; Qiao Z; Sun Y; Kang T; Zhu S; Wang S; Xiao H; Zhao C; Shen S; Xu Z; Liu H
    Oncogene; 2020 Sep; 39(36):5888-5901. PubMed ID: 32733069
    [TBL] [Abstract][Full Text] [Related]  

  • 26. MiR-27a downregulates 14-3-3θ, RUNX1, AF4, and MLL-AF4, crucial drivers of blast transformation in t(4;11) leukemia cells.
    Fioretti T; Zanobio M; Raia M; Errichiello S; Izzo B; Cattaneo F; Ammendola R; Cevenini A; Esposito G
    Cell Biochem Funct; 2022 Oct; 40(7):706-717. PubMed ID: 35981137
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Transcriptional activation of the mixed lineage leukemia-p27Kip1 pathway by a somatostatin analogue.
    Horiguchi K; Yamada M; Satoh T; Hashimoto K; Hirato J; Tosaka M; Yamada S; Mori M
    Clin Cancer Res; 2009 Apr; 15(8):2620-9. PubMed ID: 19318494
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ALL1 fusion proteins induce deregulation of EphA7 and ERK phosphorylation in human acute leukemias.
    Nakanishi H; Nakamura T; Canaani E; Croce CM
    Proc Natl Acad Sci U S A; 2007 Sep; 104(36):14442-7. PubMed ID: 17726105
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4.MLL fusion allele.
    Kowarz E; Burmeister T; Lo Nigro L; Jansen MW; Delabesse E; Klingebiel T; Dingermann T; Meyer C; Marschalek R
    Leukemia; 2007 Jun; 21(6):1232-8. PubMed ID: 17410185
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair.
    Castaño J; Herrero AB; Bursen A; González F; Marschalek R; Gutiérrez NC; Menendez P
    Oncotarget; 2016 May; 7(21):30440-52. PubMed ID: 27119507
    [TBL] [Abstract][Full Text] [Related]  

  • 31. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.
    Wilkinson AC; Ballabio E; Geng H; North P; Tapia M; Kerry J; Biswas D; Roeder RG; Allis CD; Melnick A; de Bruijn MF; Milne TA
    Cell Rep; 2013 Jan; 3(1):116-27. PubMed ID: 23352661
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Down-regulation of DLX3 expression in MLL-AF4 childhood lymphoblastic leukemias is mediated by promoter region hypermethylation.
    Campo Dell'Orto M; Banelli B; Giarin E; Accordi B; Trentin L; Romani M; te Kronnie G; Basso G
    Oncol Rep; 2007 Aug; 18(2):417-23. PubMed ID: 17611665
    [TBL] [Abstract][Full Text] [Related]  

  • 33. MLL fusion partners AF4 and AF9 interact at subnuclear foci.
    Erfurth F; Hemenway CS; de Erkenez AC; Domer PH
    Leukemia; 2004 Jan; 18(1):92-102. PubMed ID: 14603337
    [TBL] [Abstract][Full Text] [Related]  

  • 34. AF4 encodes a ubiquitous protein that in both native and MLL-AF4 fusion types localizes to subnuclear compartments.
    Li Q; Frestedt JL; Kersey JH
    Blood; 1998 Nov; 92(10):3841-7. PubMed ID: 9808577
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein.
    Sabiani S; Geppert T; Engelbrecht C; Kowarz E; Schneider G; Marschalek R
    EBioMedicine; 2015 May; 2(5):386-95. PubMed ID: 26137584
    [TBL] [Abstract][Full Text] [Related]  

  • 36. MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia.
    Kerry J; Godfrey L; Repapi E; Tapia M; Blackledge NP; Ma H; Ballabio E; O'Byrne S; Ponthan F; Heidenreich O; Roy A; Roberts I; Konopleva M; Klose RJ; Geng H; Milne TA
    Cell Rep; 2017 Jan; 18(2):482-495. PubMed ID: 28076791
    [TBL] [Abstract][Full Text] [Related]  

  • 37. MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
    Monroe SC; Jo SY; Sanders DS; Basrur V; Elenitoba-Johnson KS; Slany RK; Hess JL
    Exp Hematol; 2011 Jan; 39(1):77-86.e1-5. PubMed ID: 20854876
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The role of reciprocal fusions in MLL-r acute leukemia: studying the chromosomal translocation t(4;11).
    Wilhelm A; Marschalek R
    Oncogene; 2021 Oct; 40(42):6093-6102. PubMed ID: 34489550
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Development of a high-throughput screening-compatible assay for the discovery of inhibitors of the AF4-AF9 interaction using AlphaScreen technology.
    Watson VG; Drake KM; Peng Y; Napper AD
    Assay Drug Dev Technol; 2013 May; 11(4):253-68. PubMed ID: 23679849
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The leukemogenic fusion gene MLL-AF9 alters microRNA expression pattern and inhibits monoblastic differentiation via miR-511 repression.
    Fleischmann KK; Pagel P; von Frowein J; Magg T; Roscher AA; Schmid I
    J Exp Clin Cancer Res; 2016 Jan; 35():9. PubMed ID: 26762252
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.