BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 16171379)

  • 1. Structural perturbation and compensation by directed evolution at physiological temperature leads to thermostabilization of beta-lactamase.
    Hecky J; Müller KM
    Biochemistry; 2005 Sep; 44(38):12640-54. PubMed ID: 16171379
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A general method of terminal truncation, evolution, and re-elongation to generate enzymes of enhanced stability.
    Hecky J; Mason JM; Arndt KM; Müller KM
    Methods Mol Biol; 2007; 352():275-304. PubMed ID: 17041271
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased folding stability of TEM-1 beta-lactamase by in vitro selection.
    Kather I; Jakob RP; Dobbek H; Schmid FX
    J Mol Biol; 2008 Oct; 383(1):238-51. PubMed ID: 18706424
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploring the molecular linkage of protein stability traits for enzyme optimization by iterative truncation and evolution.
    Speck J; Hecky J; Tam HK; Arndt KM; Einsle O; Müller KM
    Biochemistry; 2012 Jun; 51(24):4850-67. PubMed ID: 22545913
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Directed evolution study of temperature adaptation in a psychrophilic enzyme.
    Miyazaki K; Wintrode PL; Grayling RA; Rubingh DN; Arnold FH
    J Mol Biol; 2000 Apr; 297(4):1015-26. PubMed ID: 10736234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Predicting the emergence of antibiotic resistance by directed evolution and structural analysis.
    Orencia MC; Yoon JS; Ness JE; Stemmer WP; Stevens RC
    Nat Struct Biol; 2001 Mar; 8(3):238-42. PubMed ID: 11224569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Noncovalent interaction energies in covalent complexes: TEM-1 beta-lactamase and beta-lactams.
    Wang X; Minasov G; Shoichet BK
    Proteins; 2002 Apr; 47(1):86-96. PubMed ID: 11870868
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increasing the thermal stability of an oligomeric protein, beta-glucuronidase.
    Flores H; Ellington AD
    J Mol Biol; 2002 Jan; 315(3):325-37. PubMed ID: 11786015
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional analyses of AmpC beta-lactamase through differential stability.
    Beadle BM; McGovern SL; Patera A; Shoichet BK
    Protein Sci; 1999 Sep; 8(9):1816-24. PubMed ID: 10493583
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Improving the thermostability of Geobacillus stearothermophilus xylanase XT6 by directed evolution and site-directed mutagenesis.
    Zhang ZG; Yi ZL; Pei XQ; Wu ZL
    Bioresour Technol; 2010 Dec; 101(23):9272-8. PubMed ID: 20691586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancing the thermostability of a novel beta-agarase AgaB through directed evolution.
    Shi C; Lu X; Ma C; Ma Y; Fu X; Yu W
    Appl Biochem Biotechnol; 2008 Oct; 151(1):51-9. PubMed ID: 18785021
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamase.
    Zaccolo M; Gherardi E
    J Mol Biol; 1999 Jan; 285(2):775-83. PubMed ID: 9878443
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Paenibacillus sp. dextranase mutant pool with improved thermostability and activity.
    Hild E; Brumbley SM; O'Shea MG; Nevalainen H; Bergquist PL
    Appl Microbiol Biotechnol; 2007 Jul; 75(5):1071-8. PubMed ID: 17426967
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Engineering thermal stability of L-asparaginase by in vitro directed evolution.
    Kotzia GA; Labrou NE
    FEBS J; 2009 Mar; 276(6):1750-61. PubMed ID: 19220855
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs.
    Wang X; Minasov G; Shoichet BK
    J Mol Biol; 2002 Jun; 320(1):85-95. PubMed ID: 12079336
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Circularly permuted beta-lactamase from Staphylococcus aureus PC1.
    Pieper U; Hayakawa K; Li Z; Herzberg O
    Biochemistry; 1997 Jul; 36(29):8767-74. PubMed ID: 9220963
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The D-methyl group in beta-lactamase evolution: evidence from the Y221G and GC1 mutants of the class C beta-lactamase of Enterobacter cloacae P99.
    Adediran SA; Zhang Z; Nukaga M; Palzkill T; Pratt RF
    Biochemistry; 2005 May; 44(20):7543-52. PubMed ID: 15895997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhancement of thermostability of fungal deglycating enzymes by directed evolution.
    Hirokawa K; Ichiyanagi A; Kajiyama N
    Appl Microbiol Biotechnol; 2008 Apr; 78(5):775-81. PubMed ID: 18246344
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Concurrent mutations in six amino acids in beta-glucuronidase improve its thermostability.
    Xiong AS; Peng RH; Cheng ZM; Li Y; Liu JG; Zhuang J; Gao F; Xu F; Qiao YS; Zhang Z; Chen JM; Yao QH
    Protein Eng Des Sel; 2007 Jul; 20(7):319-25. PubMed ID: 17557766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis of the destabilization produced by an amino-terminal tag in the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus.
    Ausili A; Cobucci-Ponzano B; Di Lauro B; D'Avino R; Scirè A; Rossi M; Tanfani F; Moracci M
    Biochimie; 2006 Jul; 88(7):807-17. PubMed ID: 16494988
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.