BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 16171463)

  • 21. Substrate-dependent modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1) by propofol in recombinant human UGT1A1 and human liver microsomes.
    Mano Y; Usui T; Kamimura H
    Basic Clin Pharmacol Toxicol; 2007 Sep; 101(3):211-4. PubMed ID: 17697043
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Protein-protein interactions between the bilirubin-conjugating UDP-glucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing.
    Rouleau M; Collin P; Bellemare J; Harvey M; Guillemette C
    Biochem J; 2013 Feb; 450(1):107-14. PubMed ID: 23148825
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.
    Hanioka N; Tanabe N; Jinno H; Tanaka-Kagawa T; Nagaoka K; Naito S; Koeda A; Narimatsu S
    Life Sci; 2010 Aug; 87(7-8):261-8. PubMed ID: 20620155
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Altered coding for a strictly conserved di-glycine in the major bilirubin UDP-glucuronosyltransferase of a Crigler-Najjar type I patient.
    Ciotti M; Yeatman MT; Sokol RJ; Owens IS
    J Biol Chem; 1995 Feb; 270(7):3284-91. PubMed ID: 7852413
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of the deletions in the UGT1A1 gene of the patients with Crigler-Najjar syndrome type I from Slovakia.
    Zmetáková I; Ferák V; Minárik G; Ficek A; Poláková H; Feráková E; Kádasi L
    Gen Physiol Biophys; 2007 Dec; 26(4):306-10. PubMed ID: 18281749
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Isolation and characterization of the monkey UDP-glucuronosyltransferase cDNA clone monUGT1A01 active on bilirubin and estrogens.
    Vallée M; Albert C; Beaudry G; Hum DW; Bélanger A
    J Steroid Biochem Mol Biol; 2001 Jun; 77(4-5):239-49. PubMed ID: 11457662
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A mutation which disrupts the hydrophobic core of the signal peptide of bilirubin UDP-glucuronosyltransferase, an endoplasmic reticulum membrane protein, causes Crigler-Najjar type II.
    Seppen J; Steenken E; Lindhout D; Bosma PJ; Elferink RP
    FEBS Lett; 1996 Jul; 390(3):294-8. PubMed ID: 8706880
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Truncated UDP-glucuronosyltransferase (UGT) from a Crigler-Najjar syndrome type II patient colocalizes with intact UGT in the endoplasmic reticulum.
    Suzuki M; Hirata M; Takagi M; Watanabe T; Iguchi T; Koiwai K; Maezawa S; Koiwai O
    J Hum Genet; 2014 Mar; 59(3):158-62. PubMed ID: 24401909
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A molecular model of the human UDP-glucuronosyltransferase 1A1, its membrane orientation, and the interactions between different parts of the enzyme.
    Laakkonen L; Finel M
    Mol Pharmacol; 2010 Jun; 77(6):931-9. PubMed ID: 20215562
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Nuclear factor κB down-regulates human UDP-glucuronosyltransferase 1A1: a novel mechanism involved in inflammation-associated hyperbilirubinaemia.
    Shiu TY; Huang TY; Huang SM; Shih YL; Chu HC; Chang WK; Hsieh TY
    Biochem J; 2013 Feb; 449(3):761-70. PubMed ID: 23130636
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Metabolism of the c-Fos/activator protein-1 inhibitor T-5224 by multiple human UDP-glucuronosyltransferase isoforms.
    Uchihashi S; Fukumoto H; Onoda M; Hayakawa H; Ikushiro S; Sakaki T
    Drug Metab Dispos; 2011 May; 39(5):803-13. PubMed ID: 21346002
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.
    Court MH; Duan SX; von Moltke LL; Greenblatt DJ; Patten CJ; Miners JO; Mackenzie PI
    J Pharmacol Exp Ther; 2001 Dec; 299(3):998-1006. PubMed ID: 11714888
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.
    Miyauchi Y; Kurita A; Yamashita R; Takamatsu T; Ikushiro S; Mackenzie PI; Tanaka Y; Ishii Y
    Biochem Biophys Res Commun; 2020 Apr; 525(2):348-353. PubMed ID: 32093886
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Crigler-Najjar syndrome type 2.
    Huang CS; Tan N; Yang SS; Sung YC; Huang MJ
    J Formos Med Assoc; 2006 Nov; 105(11):950-3. PubMed ID: 17098698
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Homodimerization of human bilirubin-uridine-diphosphoglucuronate glucuronosyltransferase-1 (UGT1A1) and its functional implications.
    Ghosh SS; Sappal BS; Kalpana GV; Lee SW; Chowdhury JR; Chowdhury NR
    J Biol Chem; 2001 Nov; 276(45):42108-15. PubMed ID: 11546782
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Compound heterozygosity of a novel exon 3 frameshift (p.R357P fs*24) mutation and Y486D mutation in exon 5 of the UGT1A1 gene in a Thai infant with Crigler-Najjar syndrome type 2.
    Tesapirat L; Nilyanimit P; Wanlapakorn N; Poovorawan Y
    Genet Mol Res; 2015 Apr; 14(2):3293-9. PubMed ID: 25966095
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A case of anorexia nervosa with hyperbilirubinaemia in a patient homozygous for a mutation in the bilirubin UDP-glucuronosyltransferase gene.
    Maruo Y; Wada S; Yamamoto K; Sato H; Yamano T; Shimada M
    Eur J Pediatr; 1999 Jul; 158(7):547-9. PubMed ID: 10412811
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in CHO cells.
    Malfatti MA; Wu RW; Felton JS
    Mutat Res; 2005 Mar; 570(2):205-14. PubMed ID: 15708579
    [TBL] [Abstract][Full Text] [Related]  

  • 39. UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics.
    Wen Z; Tallman MN; Ali SY; Smith PC
    Drug Metab Dispos; 2007 Mar; 35(3):371-80. PubMed ID: 17151191
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.
    Kato Y; Ikushiro S; Emi Y; Tamaki S; Suzuki H; Sakaki T; Yamada S; Degawa M
    Drug Metab Dispos; 2008 Jan; 36(1):51-5. PubMed ID: 17908920
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.