212 related articles for article (PubMed ID: 16173921)
1. Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability.
Galán M; Vincent O; Roncero I; Azriel S; Boix-Pallares P; Delgado-Alvarez E; Díaz-Cadórniga F; Blázquez E; Navas MA
Biochem J; 2006 Jan; 393(Pt 1):389-96. PubMed ID: 16173921
[TBL] [Abstract][Full Text] [Related]
2. Insight into the biochemical characteristics of a novel glucokinase gene mutation.
Shen Y; Cai M; Liang H; Wang H; Weng J
Hum Genet; 2011 Mar; 129(3):231-8. PubMed ID: 21104275
[TBL] [Abstract][Full Text] [Related]
3. Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity.
García-Herrero CM; Galán M; Vincent O; Flández B; Gargallo M; Delgado-Alvarez E; Blázquez E; Navas MA
Diabetologia; 2007 Feb; 50(2):325-33. PubMed ID: 17186219
[TBL] [Abstract][Full Text] [Related]
4. GCK-MODY diabetes as a protein misfolding disease: the mutation R275C promotes protein misfolding, self-association and cellular degradation.
Negahdar M; Aukrust I; Molnes J; Solheim MH; Johansson BB; Sagen JV; Dahl-Jørgensen K; Kulkarni RN; Søvik O; Flatmark T; Njølstad PR; Bjørkhaug L
Mol Cell Endocrinol; 2014 Jan; 382(1):55-65. PubMed ID: 24001579
[TBL] [Abstract][Full Text] [Related]
5. Functional Characterization of a Novel Heterozygous Mutation in the Glucokinase Gene That Causes MODY2 in Chinese Pedigrees.
Jiang F; Yan J; Zhang R; Ma X; Bao Y; Gu Y; Hu C
Front Endocrinol (Lausanne); 2021; 12():803992. PubMed ID: 34956103
[TBL] [Abstract][Full Text] [Related]
6. Insights into pathogenesis of five novel GCK mutations identified in Chinese MODY patients.
Liu L; Liu Y; Ge X; Liu X; Chen C; Wang Y; Li M; Yin J; Zhang J; Chen Y; Zhang R; Jiang Y; Zhao W; Yang D; Zheng T; Lu M; Zhuang L; Jiang M
Metabolism; 2018 Dec; 89():8-17. PubMed ID: 30257192
[TBL] [Abstract][Full Text] [Related]
7. Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young.
Gloyn AL; Odili S; Zelent D; Buettger C; Castleden HA; Steele AM; Stride A; Shiota C; Magnuson MA; Lorini R; d'Annunzio G; Stanley CA; Kwagh J; van Schaftingen E; Veiga-da-Cunha M; Barbetti F; Dunten P; Han Y; Grimsby J; Taub R; Ellard S; Hattersley AT; Matschinsky FM
J Biol Chem; 2005 Apr; 280(14):14105-13. PubMed ID: 15677479
[TBL] [Abstract][Full Text] [Related]
8. Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme.
Liang Y; Kesavan P; Wang LQ; Niswender K; Tanizawa Y; Permutt MA; Magnuson MA; Matschinsky FM
Biochem J; 1995 Jul; 309 ( Pt 1)(Pt 1):167-73. PubMed ID: 7619052
[TBL] [Abstract][Full Text] [Related]
9. Characterization of glucokinase polymorphisms associated with maturity-onset diabetes of the young (MODY2) in Jordanian population.
Al-Sheyab F; Khamaiseh E; Halaweh MA; Khaul RW
Tsitol Genet; 2009; 43(5):58-63. PubMed ID: 20458967
[TBL] [Abstract][Full Text] [Related]
10. Identification and functional characterisation of novel glucokinase mutations causing maturity-onset diabetes of the young in Slovakia.
Valentínová L; Beer NL; Staník J; Tribble ND; van de Bunt M; Hučková M; Barrett A; Klimeš I; Gašperíková D; Gloyn AL
PLoS One; 2012; 7(4):e34541. PubMed ID: 22493702
[TBL] [Abstract][Full Text] [Related]
11. A report of 2 new cases of MODY2 and review of the literature: implications in the search for type 2 diabetes drugs.
Shammas C; Neocleous V; Phelan MM; Lian LY; Skordis N; Phylactou LA
Metabolism; 2013 Nov; 62(11):1535-42. PubMed ID: 23890519
[TBL] [Abstract][Full Text] [Related]
12. Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing.
García-Herrero CM; Rubio-Cabezas O; Azriel S; Gutierrez-Nogués A; Aragonés A; Vincent O; Campos-Barros A; Argente J; Navas MA
PLoS One; 2012; 7(1):e30518. PubMed ID: 22291974
[TBL] [Abstract][Full Text] [Related]
13. Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia.
Osbak KK; Colclough K; Saint-Martin C; Beer NL; Bellanné-Chantelot C; Ellard S; Gloyn AL
Hum Mutat; 2009 Nov; 30(11):1512-26. PubMed ID: 19790256
[TBL] [Abstract][Full Text] [Related]
14. Glucokinase mutations in pediatric patients with impaired fasting glucose.
Aloi C; Salina A; Minuto N; Tallone R; Lugani F; Mascagni A; Mazza O; Cassanello M; Maghnie M; d'Annunzio G
Acta Diabetol; 2017 Oct; 54(10):913-923. PubMed ID: 28726111
[TBL] [Abstract][Full Text] [Related]
15. Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): different glucokinase defects lead to a common phenotype.
Miller SP; Anand GR; Karschnia EJ; Bell GI; LaPorte DC; Lange AJ
Diabetes; 1999 Aug; 48(8):1645-51. PubMed ID: 10426385
[TBL] [Abstract][Full Text] [Related]
16. Evolution- and structure-based computational strategy reveals the impact of deleterious missense mutations on MODY 2 (maturity-onset diabetes of the young, type 2).
George DC; Chakraborty C; Haneef SA; Nagasundaram N; Chen L; Zhu H
Theranostics; 2014; 4(4):366-85. PubMed ID: 24578721
[TBL] [Abstract][Full Text] [Related]
17. Biochemical characterization of novel glucokinase mutations isolated from Spanish maturity-onset diabetes of the young (MODY2) patients.
Estalella I; Garcia-Gimeno MA; Marina A; Castaño L; Sanz P
J Hum Genet; 2008; 53(5):460-466. PubMed ID: 18322640
[TBL] [Abstract][Full Text] [Related]
18. Functional characterization of MODY2 mutations in the nuclear export signal of glucokinase.
Gutierrez-Nogués A; García-Herrero CM; Oriola J; Vincent O; Navas MA
Biochim Biophys Acta Mol Basis Dis; 2018 Jul; 1864(7):2385-2394. PubMed ID: 29704611
[TBL] [Abstract][Full Text] [Related]
19. Genetic and bioinformatics analysis of four novel GCK missense variants detected in Caucasian families with GCK-MODY phenotype.
Costantini S; Malerba G; Contreas G; Corradi M; Marin Vargas SP; Giorgetti A; Maffeis C
Clin Genet; 2015 May; 87(5):440-7. PubMed ID: 24735133
[TBL] [Abstract][Full Text] [Related]
20. Analysis of mutations in the glucokinase gene in people clinically characterized as MODY2 without a family history of diabetes.
Lopez AP; de Dios A; Chiesa I; Perez MS; Frechtel GD
Diabetes Res Clin Pract; 2016 Aug; 118():38-43. PubMed ID: 27289208
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]