318 related articles for article (PubMed ID: 16176182)
1. Analysis of the hypoxia-sensing pathway in Drosophila melanogaster.
Arquier N; Vigne P; Duplan E; Hsu T; Therond PP; Frelin C; D'Angelo G
Biochem J; 2006 Jan; 393(Pt 2):471-80. PubMed ID: 16176182
[TBL] [Abstract][Full Text] [Related]
2. Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation.
D'Angelo G; Duplan E; Vigne P; Frelin C
J Biol Chem; 2003 Apr; 278(17):15406-11. PubMed ID: 12586829
[TBL] [Abstract][Full Text] [Related]
3. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
D'Angelo G; Duplan E; Boyer N; Vigne P; Frelin C
J Biol Chem; 2003 Oct; 278(40):38183-7. PubMed ID: 12876291
[TBL] [Abstract][Full Text] [Related]
4. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
5. von Hippel-Lindau β-domain-luciferase fusion protein as a bioluminescent hydroxyproline sensor for a hypoxia-inducible factor prolyl hydroxylase assay.
Hong S; Yum S; Ha NC; Jung Y
Anal Biochem; 2010 Dec; 407(2):220-5. PubMed ID: 20705044
[TBL] [Abstract][Full Text] [Related]
6. The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression.
Mortimer NT; Moberg KH
PLoS Genet; 2013; 9(2):e1003314. PubMed ID: 23459416
[TBL] [Abstract][Full Text] [Related]
7. Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro.
Pan Y; Mansfield KD; Bertozzi CC; Rudenko V; Chan DA; Giaccia AJ; Simon MC
Mol Cell Biol; 2007 Feb; 27(3):912-25. PubMed ID: 17101781
[TBL] [Abstract][Full Text] [Related]
8. Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion.
Demidenko ZN; Rapisarda A; Garayoa M; Giannakakou P; Melillo G; Blagosklonny MV
Oncogene; 2005 Jul; 24(30):4829-38. PubMed ID: 15897903
[TBL] [Abstract][Full Text] [Related]
9. Hypoxia-inducible factor 1 (HIF-1) pathway.
Semenza GL
Sci STKE; 2007 Oct; 2007(407):cm8. PubMed ID: 17925579
[TBL] [Abstract][Full Text] [Related]
10. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.
Tanimoto K; Makino Y; Pereira T; Poellinger L
EMBO J; 2000 Aug; 19(16):4298-309. PubMed ID: 10944113
[TBL] [Abstract][Full Text] [Related]
11. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
Chowdhury R; McDonough MA; Mecinović J; Loenarz C; Flashman E; Hewitson KS; Domene C; Schofield CJ
Structure; 2009 Jul; 17(7):981-9. PubMed ID: 19604478
[TBL] [Abstract][Full Text] [Related]
12. Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.
Lee HY; Lee T; Lee N; Yang EG; Lee C; Lee J; Moon EY; Ha J; Park H
Carcinogenesis; 2011 May; 32(5):703-12. PubMed ID: 21335603
[TBL] [Abstract][Full Text] [Related]
13. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.
Callapina M; Zhou J; Schnitzer S; Metzen E; Lohr C; Deitmer JW; Brüne B
Exp Cell Res; 2005 May; 306(1):274-84. PubMed ID: 15878351
[TBL] [Abstract][Full Text] [Related]
14. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
Jaakkola P; Mole DR; Tian YM; Wilson MI; Gielbert J; Gaskell SJ; von Kriegsheim A; Hebestreit HF; Mukherji M; Schofield CJ; Maxwell PH; Pugh CW; Ratcliffe PJ
Science; 2001 Apr; 292(5516):468-72. PubMed ID: 11292861
[TBL] [Abstract][Full Text] [Related]
15. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.
Foxler DE; Bridge KS; James V; Webb TM; Mee M; Wong SC; Feng Y; Constantin-Teodosiu D; Petursdottir TE; Bjornsson J; Ingvarsson S; Ratcliffe PJ; Longmore GD; Sharp TV
Nat Cell Biol; 2012 Jan; 14(2):201-8. PubMed ID: 22286099
[TBL] [Abstract][Full Text] [Related]
16. LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of VHL in a colon cancer cell line.
Lee K; Kang JE; Park SK; Jin Y; Chung KS; Kim HM; Lee K; Kang MR; Lee MK; Song KB; Yang EG; Lee JJ; Won M
Biochem Pharmacol; 2010 Oct; 80(7):982-9. PubMed ID: 20599784
[TBL] [Abstract][Full Text] [Related]
17. HIF-1α Hydroxyprolines Modulate Oxygen-Dependent Protein Stability Via Single VHL Interface With Comparable Effect on Ubiquitination Rate.
He W; Batty-Stuart S; Lee JE; Ohh M
J Mol Biol; 2021 Nov; 433(22):167244. PubMed ID: 34537235
[TBL] [Abstract][Full Text] [Related]
18. Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms.
Martín-Puig S; Temes E; Olmos G; Jones DR; Aragonés J; Landázuri MO
J Biol Chem; 2004 Mar; 279(10):9504-11. PubMed ID: 14681229
[TBL] [Abstract][Full Text] [Related]
19. In silico investigation of PHD-3 specific HIF1-α proline 567 hydroxylation: a new player in the VHL/HIF-1α interaction pathway?
Minervini G; Masiero A; Moro S; Tosatto SC
FEBS Lett; 2013 Sep; 587(18):2996-3001. PubMed ID: 23886708
[TBL] [Abstract][Full Text] [Related]
20. Activation of hypoxia-induced transcription in normoxia.
Hägg M; Wennström S
Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]