249 related articles for article (PubMed ID: 1617622)
21. Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
Peters GJ
Nucleosides Nucleotides Nucleic Acids; 2018; 37(6):329-339. PubMed ID: 29723133
[TBL] [Abstract][Full Text] [Related]
22. Structural and functional comparison of agents interfering with dihydroorotate, succinate and NADH oxidation of rat liver mitochondria.
Jöckel J; Wendt B; Löffler M
Biochem Pharmacol; 1998 Oct; 56(8):1053-60. PubMed ID: 9776318
[TBL] [Abstract][Full Text] [Related]
23. Anti-arthritic effects of KF20444, a new immunosuppressive compound inhibiting dihydroorotate dehydrogenase, on rat collagen-induced arthritis.
Kobayashi K; Nakashima A; Nagata H; Nakajima H; Yamaguchi K; Sato S; Miki I
Inflamm Res; 2001 Jan; 50(1):24-31. PubMed ID: 11235018
[TBL] [Abstract][Full Text] [Related]
24. The relation between inhibition of cell growth and of dihydroorotic acid dehydrogenase by brequinar sodium.
de Kant E; Pinedo HM; Laurensse E; Peters GJ
Cancer Lett; 1989 Jul; 46(2):123-7. PubMed ID: 2546667
[TBL] [Abstract][Full Text] [Related]
25. Expression and characterization of E. coli-produced soluble, functional human dihydroorotate dehydrogenase: a potential target for immunosuppression.
Neidhardt EA; Punreddy SR; McLean JE; Hedstrom L; Grossman TH
J Mol Microbiol Biotechnol; 1999 Aug; 1(1):183-8. PubMed ID: 10941801
[TBL] [Abstract][Full Text] [Related]
26. Catalytic properties of dihydroorotate dehydrogenase from Saccharomyces cerevisiae: studies on pH, alternate substrates, and inhibitors.
Jordan DB; Bisaha JJ; Picollelli MA
Arch Biochem Biophys; 2000 Jun; 378(1):84-92. PubMed ID: 10871048
[TBL] [Abstract][Full Text] [Related]
27. A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.
DeRatt LG; Christine Pietsch E; Tanner A; Shaffer P; Jacoby E; Wang W; Kazmi F; Zhang X; Attar RM; Edwards JP; Kuduk SD
Bioorg Med Chem Lett; 2020 Nov; 30(22):127589. PubMed ID: 33007394
[TBL] [Abstract][Full Text] [Related]
28. Recombinant human dihydroorotate dehydrogenase: expression, purification, and characterization of a catalytically functional truncated enzyme.
Copeland RA; Davis JP; Dowling RL; Lombardo D; Murphy KB; Patterson TA
Arch Biochem Biophys; 1995 Oct; 323(1):79-86. PubMed ID: 7487077
[TBL] [Abstract][Full Text] [Related]
29. Phase I clinical and pharmacokinetic trial of Brequinar sodium (DuP 785; NSC 368390).
Arteaga CL; Brown TD; Kuhn JG; Shen HS; O'Rourke TJ; Beougher K; Brentzel HJ; Von Hoff DD; Weiss GR
Cancer Res; 1989 Aug; 49(16):4648-53. PubMed ID: 2743343
[TBL] [Abstract][Full Text] [Related]
30. The relationship between dihydroorotic acid dehydrogenase and in vitro and in vivo cytostatic effects of brequinar sodium (DUP-785; NSC 368390).
Peters GJ; Laurensse E; de Kant E; Nadal JC; Pinedo HM
Adv Exp Med Biol; 1989; 253B():375-82. PubMed ID: 2558540
[No Abstract] [Full Text] [Related]
31. Effects of brequinar and ciprofloxacin on de novo nucleotide biosynthesis in mouse L1210 leukemia.
Lyons SD; Christopherson RI
Biochem Int; 1990 Dec; 22(6):939-49. PubMed ID: 1965281
[TBL] [Abstract][Full Text] [Related]
32. Dihydrooxonate is a substrate of dihydroorotate dehydrogenase (DHOD) providing evidence for involvement of cysteine and serine residues in base catalysis.
Björnberg O; Jordan DB; Palfey BA; Jensen KF
Arch Biochem Biophys; 2001 Jul; 391(2):286-94. PubMed ID: 11437361
[TBL] [Abstract][Full Text] [Related]
33. Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domain.
Hansen M; Le Nours J; Johansson E; Antal T; Ullrich A; Löffler M; Larsen S
Protein Sci; 2004 Apr; 13(4):1031-42. PubMed ID: 15044733
[TBL] [Abstract][Full Text] [Related]
34. Site of action of two novel pyrimidine biosynthesis inhibitors accurately predicted by the compare program.
Cleaveland ES; Monks A; Vaigro-Wolff A; Zaharevitz DW; Paull K; Ardalan K; Cooney DA; Ford H
Biochem Pharmacol; 1995 Mar; 49(7):947-54. PubMed ID: 7741767
[TBL] [Abstract][Full Text] [Related]
35. New inhibitors of dihydroorotate dehydrogenase (DHODH) based on the 4-hydroxy-1,2,5-oxadiazol-3-yl (hydroxyfurazanyl) scaffold.
Lolli ML; Giorgis M; Tosco P; Foti A; Fruttero R; Gasco A
Eur J Med Chem; 2012 Mar; 49():102-9. PubMed ID: 22245049
[TBL] [Abstract][Full Text] [Related]
36. Antitumor activity of brequinar sodium (Dup-785) against human head and neck squamous cell carcinoma xenografts.
Braakhuis BJ; van Dongen GA; Peters GJ; van Walsum M; Snow GB
Cancer Lett; 1990 Feb; 49(2):133-7. PubMed ID: 2306706
[TBL] [Abstract][Full Text] [Related]
37. Identification of dihydroorotate dehydrogenase as a relevant drug target for 1-hydroxyquinolones in Toxoplasma gondii.
Hegewald J; Gross U; Bohne W
Mol Biochem Parasitol; 2013 Jul; 190(1):6-15. PubMed ID: 23747278
[TBL] [Abstract][Full Text] [Related]
38. The activity of Escherichia coli dihydroorotate dehydrogenase is dependent on a conserved loop identified by sequence homology, mutagenesis, and limited proteolysis.
Björnberg O; Grüner AC; Roepstorff P; Jensen KF
Biochemistry; 1999 Mar; 38(10):2899-908. PubMed ID: 10074342
[TBL] [Abstract][Full Text] [Related]
39. Active site of dihydroorotate dehydrogenase A from Lactococcus lactis investigated by chemical modification and mutagenesis.
Björnberg O; Rowland P; Larsen S; Jensen KF
Biochemistry; 1997 Dec; 36(51):16197-205. PubMed ID: 9405053
[TBL] [Abstract][Full Text] [Related]
40. Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria.
Hey-Mogensen M; Goncalves RL; Orr AL; Brand MD
Free Radic Biol Med; 2014 Jul; 72():149-55. PubMed ID: 24746616
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
