BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

678 related articles for article (PubMed ID: 16176978)

  • 1. PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway.
    Hamanaka RB; Bennett BS; Cullinan SB; Diehl JA
    Mol Biol Cell; 2005 Dec; 16(12):5493-501. PubMed ID: 16176978
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PERK mediates cell-cycle exit during the mammalian unfolded protein response.
    Brewer JW; Diehl JA
    Proc Natl Acad Sci U S A; 2000 Nov; 97(23):12625-30. PubMed ID: 11035797
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PKR and PKR-like endoplasmic reticulum kinase induce the proteasome-dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2alpha phosphorylation.
    Raven JF; Baltzis D; Wang S; Mounir Z; Papadakis AI; Gao HQ; Koromilas AE
    J Biol Chem; 2008 Feb; 283(6):3097-3108. PubMed ID: 18063576
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.
    Kimball SR; Clemens MJ; Tilleray VJ; Wek RC; Horetsky RL; Jefferson LS
    Biochem Biophys Res Commun; 2001 Jan; 280(1):293-300. PubMed ID: 11162513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
    Shi J; Li Z; Xu R; Zhang J; Zhou Q; Gao R; Lu H; Lan Y; Zhao K; He H; Gao F; He W
    J Virol; 2022 Jan; 96(1):e0169521. PubMed ID: 34643429
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I Interferon Production.
    Xue M; Fu F; Ma Y; Zhang X; Li L; Feng L; Liu P
    J Virol; 2018 Aug; 92(15):. PubMed ID: 29769338
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity.
    Roobol A; Roobol J; Bastide A; Knight JR; Willis AE; Smales CM
    Biochem J; 2015 Jan; 465(2):213-25. PubMed ID: 25329545
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.
    Koumenis C; Naczki C; Koritzinsky M; Rastani S; Diehl A; Sonenberg N; Koromilas A; Wouters BG
    Mol Cell Biol; 2002 Nov; 22(21):7405-16. PubMed ID: 12370288
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of G(1) arrest and apoptosis in hypoxia by PERK and GCN2-mediated eIF2alpha phosphorylation.
    Liu Y; László C; Liu Y; Liu W; Chen X; Evans SC; Wu S
    Neoplasia; 2010 Jan; 12(1):61-8. PubMed ID: 20072654
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional characterization of Drosophila melanogaster PERK eukaryotic initiation factor 2alpha (eIF2alpha) kinase.
    Pomar N; Berlanga JJ; Campuzano S; Hernández G; Elías M; de Haro C
    Eur J Biochem; 2003 Jan; 270(2):293-306. PubMed ID: 12605680
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Human Cytomegalovirus Endoplasmic Reticulum-Resident Glycoprotein UL148 Activates the Unfolded Protein Response.
    Siddiquey MNA; Zhang H; Nguyen CC; Domma AJ; Kamil JP
    J Virol; 2018 Oct; 92(20):. PubMed ID: 30045994
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
    Guan BJ; Krokowski D; Majumder M; Schmotzer CL; Kimball SR; Merrick WC; Koromilas AE; Hatzoglou M
    J Biol Chem; 2014 May; 289(18):12593-611. PubMed ID: 24648524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. eIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver.
    Dang Do AN; Kimball SR; Cavener DR; Jefferson LS
    Physiol Genomics; 2009 Aug; 38(3):328-41. PubMed ID: 19509078
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methods for analyzing eIF2 kinases and translational control in the unfolded protein response.
    Teske BF; Baird TD; Wek RC
    Methods Enzymol; 2011; 490():333-56. PubMed ID: 21266259
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian ECD Protein Is a Novel Negative Regulator of the PERK Arm of the Unfolded Protein Response.
    Olou AA; Sarkar A; Bele A; Gurumurthy CB; Mir RA; Ammons SA; Mirza S; Saleem I; Urano F; Band H; Band V
    Mol Cell Biol; 2017 Sep; 37(18):. PubMed ID: 28652267
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The involvement of endoplasmic reticulum stress in the suppression of colorectal tumorigenesis by tolfenamic acid.
    Zhang X; Lee SH; Min KW; McEntee MF; Jeong JB; Li Q; Baek SJ
    Cancer Prev Res (Phila); 2013 Dec; 6(12):1337-47. PubMed ID: 24104354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GCN2 phosphorylation of eIF2alpha activates NF-kappaB in response to UV irradiation.
    Jiang HY; Wek RC
    Biochem J; 2005 Jan; 385(Pt 2):371-80. PubMed ID: 15355306
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stress.
    DuRose JB; Scheuner D; Kaufman RJ; Rothblum LI; Niwa M
    Mol Cell Biol; 2009 Aug; 29(15):4295-307. PubMed ID: 19470760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum.
    Wu S; Hu Y; Wang JL; Chatterjee M; Shi Y; Kaufman RJ
    J Biol Chem; 2002 May; 277(20):18077-83. PubMed ID: 11877419
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death.
    De Simone V; Bevivino G; Sedda S; Izzo R; Laudisi F; Dinallo V; Franzè E; Colantoni A; Ortenzi A; Salvatori S; Rossi P; Sica GS; Fantini MC; Stolfi C; Monteleone G
    Cell Death Dis; 2017 Mar; 8(3):e2681. PubMed ID: 28300830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.