BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

485 related articles for article (PubMed ID: 16179381)

  • 1. Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease.
    Bauman DR; Steckelbroeck S; Williams MV; Peehl DM; Penning TM
    Mol Endocrinol; 2006 Feb; 20(2):444-58. PubMed ID: 16179381
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.
    Rizner TL; Lin HK; Peehl DM; Steckelbroeck S; Bauman DR; Penning TM
    Endocrinology; 2003 Jul; 144(7):2922-32. PubMed ID: 12810547
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.
    Blouin K; Richard C; Brochu G; Hould FS; Lebel S; Marceau S; Biron S; Luu-The V; Tchernof A
    J Endocrinol; 2006 Dec; 191(3):637-49. PubMed ID: 17170221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of the androgenic response by recombinant human 11-cis retinol dehydrogenase.
    Huang XF; Luu-The V
    J Steroid Biochem Mol Biol; 2001 May; 77(2-3):129-33. PubMed ID: 11377978
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression.
    Yang Q; Titus MA; Fung KM; Lin HK
    J Cell Biochem; 2008 Aug; 104(5):1612-24. PubMed ID: 18320593
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism.
    He XY; Merz G; Yang YZ; Pullakart R; Mehta P; Schulz H; Yang SY
    Biochim Biophys Acta; 2000 Apr; 1484(2-3):267-77. PubMed ID: 10760475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Partitioning of 5alpha-dihydrotestosterone and 5alpha-androstane-3alpha, 17beta-diol activated pathways for stimulating human prostate cancer LNCaP cell proliferation.
    Nunlist EH; Dozmorov I; Tang Y; Cowan R; Centola M; Lin HK
    J Steroid Biochem Mol Biol; 2004 Jul; 91(3):157-70. PubMed ID: 15276623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dissection of the physiological interconversion of 5alpha-DHT and 3alpha-diol by rat 3alpha-HSD via transient kinetics shows that the chemical step is rate-determining: effect of mutating cofactor and substrate-binding pocket residues on catalysis.
    Heredia VV; Penning TM
    Biochemistry; 2004 Sep; 43(38):12028-37. PubMed ID: 15379543
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer.
    Bauman DR; Steckelbroeck S; Peehl DM; Penning TM
    Endocrinology; 2006 Dec; 147(12):5806-16. PubMed ID: 16959841
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Androgen formation and metabolism in the pulmonary epithelial cell line A549: expression of 17beta-hydroxysteroid dehydrogenase type 5 and 3alpha-hydroxysteroid dehydrogenase type 3.
    Provost PR; Blomquist CH; Godin C; Huang XF; Flamand N; Luu-The V; Nadeau D; Tremblay Y
    Endocrinology; 2000 Aug; 141(8):2786-94. PubMed ID: 10919264
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
    Penning TM; Burczynski ME; Jez JM; Hung CF; Lin HK; Ma H; Moore M; Palackal N; Ratnam K
    Biochem J; 2000 Oct; 351(Pt 1):67-77. PubMed ID: 10998348
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Opposing changes in 3alpha-hydroxysteroid dehydrogenase oxidative and reductive activities in rat leydig cells during pubertal development.
    Ge RS; Hardy DO; Catterall JF; Hardy MP
    Biol Reprod; 1999 Apr; 60(4):855-60. PubMed ID: 10084958
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of human type 3 3alpha-hydroxysteroid dehydrogenase (AKR1C2) in androgen metabolism of prostate cancer cells.
    Rizner TL; Lin HK; Penning TM
    Chem Biol Interact; 2003 Feb; 143-144():401-9. PubMed ID: 12604227
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pre-receptor regulation of the androgen receptor.
    Penning TM; Jin Y; Rizner TL; Bauman DR
    Mol Cell Endocrinol; 2008 Jan; 281(1-2):1-8. PubMed ID: 18060684
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative 3alpha-hydroxysteroid dehydrogenase activity of human type 10 17beta-hydroxysteroid dehydrogenase.
    He XY; Yang YZ; Peehl DM; Lauderdale A; Schulz H; Yang SY
    J Steroid Biochem Mol Biol; 2003 Nov; 87(2-3):191-8. PubMed ID: 14672739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.
    Bellemare V; Labrie F; Luu-The V
    J Steroid Biochem Mol Biol; 2006 Jan; 98(1):18-24. PubMed ID: 16191478
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Formation of 5α-dihydrotestosterone from 5α-androstane-3α,17β-diol in prostate cancer LAPC-4 cells - Identifying inhibitors of non-classical pathways producing the most potent androgen.
    Boutin S; Roy J; Maltais R; Poirier D
    Bioorg Med Chem Lett; 2020 Jan; 30(2):126783. PubMed ID: 31753699
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution.
    Lin HK; Jez JM; Schlegel BP; Peehl DM; Pachter JA; Penning TM
    Mol Endocrinol; 1997 Dec; 11(13):1971-84. PubMed ID: 9415401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate.
    Biswas MG; Russell DW
    J Biol Chem; 1997 Jun; 272(25):15959-66. PubMed ID: 9188497
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism.
    Steiner AZ; Chang L; Ji Q; Ookhtens M; Stolz A; Paulson RJ; Stanczyk FZ
    J Clin Endocrinol Metab; 2008 Apr; 93(4):1298-303. PubMed ID: 18252781
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.