These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 16180992)

  • 21. HIS-388, a novel orally active and long-acting 11β-hydroxysteroid dehydrogenase type 1 inhibitor, ameliorates insulin sensitivity and glucose intolerance in diet-induced obesity and nongenetic type 2 diabetic murine models.
    Okazaki S; Takahashi T; Iwamura T; Nakaki J; Sekiya Y; Yagi M; Kumagai H; Sato M; Sakami S; Nitta A; Kawai K; Kainoh M
    J Pharmacol Exp Ther; 2014 Oct; 351(1):181-9. PubMed ID: 25100752
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Green tea and one of its constituents, Epigallocatechine-3-gallate, are potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.
    Hintzpeter J; Stapelfeld C; Loerz C; Martin HJ; Maser E
    PLoS One; 2014; 9(1):e84468. PubMed ID: 24404164
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening.
    Schuster D; Maurer EM; Laggner C; Nashev LG; Wilckens T; Langer T; Odermatt A
    J Med Chem; 2006 Jun; 49(12):3454-66. PubMed ID: 16759088
    [TBL] [Abstract][Full Text] [Related]  

  • 24. In vivo activity of 11β-hydroxysteroid dehydrogenase type 1 in man: effects of prednisolone and chenodesoxycholic acid.
    Diederich S; Quinkler M; Mai K; Schöneshöfer M; Baehr V; Pfeiffer A; Oelkers W; Eigendorff E
    Horm Metab Res; 2011 Jan; 43(1):66-71. PubMed ID: 20925019
    [TBL] [Abstract][Full Text] [Related]  

  • 25. 2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
    Johansson L; Fotsch C; Bartberger MD; Castro VM; Chen M; Emery M; Gustafsson S; Hale C; Hickman D; Homan E; Jordan SR; Komorowski R; Li A; McRae K; Moniz G; Matsumoto G; Orihuela C; Palm G; Veniant M; Wang M; Williams M; Zhang J
    J Med Chem; 2008 May; 51(10):2933-43. PubMed ID: 18419108
    [TBL] [Abstract][Full Text] [Related]  

  • 26. 17Beta-estradiol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rodent adipocytes.
    Tagawa N; Yuda R; Kubota S; Wakabayashi M; Yamaguchi Y; Kiyonaga D; Mori N; Minamitani E; Masuzaki H; Kobayashi Y
    J Endocrinol; 2009 Jul; 202(1):131-9. PubMed ID: 19380458
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes.
    Gathercole LL; Stewart PM
    J Steroid Biochem Mol Biol; 2010 Oct; 122(1-3):21-7. PubMed ID: 20347978
    [TBL] [Abstract][Full Text] [Related]  

  • 28. High capacity homogeneous non-radioactive cortisol detection assays for human 11beta-hydroxysteroid dehydrogenase type 1.
    Yu V; Tudor Y; Hale C; Plant M; Kim KW; Wang M; Nguyen Y; Miguel TS; Chen M; Nybo R; Baumgartner J; Kurzeja RJ; Powers D
    Assay Drug Dev Technol; 2007 Feb; 5(1):105-15. PubMed ID: 17355203
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1.
    Balázs Z; Nashev LG; Chandsawangbhuwana C; Baker ME; Odermatt A
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):117-22. PubMed ID: 19010388
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa.
    Jun YJ; Park SJ; Kim TH; Lee SH; Lee KJ; Hwang SM; Lee SH
    J Allergy Clin Immunol; 2014 Oct; 134(4):926-934.e6. PubMed ID: 24810847
    [TBL] [Abstract][Full Text] [Related]  

  • 31. 7alpha- and 7beta-hydroxy-epiandrosterone as substrates and inhibitors for the human 11beta-hydroxysteroid dehydrogenase type 1.
    Hennebert O; Pernelle C; Ferroud C; Morfin R
    J Steroid Biochem Mol Biol; 2007; 105(1-5):159-65. PubMed ID: 17624766
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, UI-1499.
    Byun SY; Shin YJ; Nam KY; Hong SP; Ahn SK
    Life Sci; 2015 Jan; 120():1-7. PubMed ID: 25447448
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Small molecule 11β-hydroxysteroid dehydrogenase type 1 inhibitors.
    Sun D; Wang M; Wang Z
    Curr Top Med Chem; 2011; 11(12):1464-75. PubMed ID: 21510838
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a promising therapeutic target.
    Wamil M; Seckl JR
    Drug Discov Today; 2007 Jul; 12(13-14):504-20. PubMed ID: 17631244
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice.
    Dhanesha N; Joharapurkar A; Shah G; Kshirsagar S; Dhote V; Sharma A; Jain M
    Clin Exp Pharmacol Physiol; 2012 Jan; 39(1):69-77. PubMed ID: 22060140
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design, synthesis, and biological evaluation of 1,4-diaryl-1,4-dihydropyrazines as novel 11β-HSD1 inhibitors.
    Duan X; Xin H; Yan H
    Biol Pharm Bull; 2014; 37(5):840-6. PubMed ID: 24790006
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.
    Hult M; Shafqat N; Elleby B; Mitschke D; Svensson S; Forsgren M; Barf T; Vallgårda J; Abrahmsen L; Oppermann U
    Mol Cell Endocrinol; 2006 Mar; 248(1-2):26-33. PubMed ID: 16431016
    [TBL] [Abstract][Full Text] [Related]  

  • 38. An in vitro microdialysis methodology to study 11beta-hydroxysteroid dehydrogenase type 1 enzyme activity in liver microsomes.
    Sun L; Stenken JA; Yang AY; Zhao JJ; Musson DG
    Anal Biochem; 2007 Nov; 370(1):26-37. PubMed ID: 17765862
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Su X; Vicker N; Trusselle M; Halem H; Culler MD; Potter BV
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):169-73. PubMed ID: 18775471
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Development of a high-throughput cell-based assay for 11beta-hydroxysteroid dehydrogenase type 1 using BacMam technology.
    Wang DY; Lu Q; Walsh SL; Payne L; Modha SS; Scott MJ; Sweitzer TD; Ames RS; Krosky DJ; Li H
    Mol Biotechnol; 2008 Jun; 39(2):127-34. PubMed ID: 18327553
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.