These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 16180992)

  • 41. 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: a review of recent patents.
    Boyle CD; Kowalski TJ
    Expert Opin Ther Pat; 2009 Jun; 19(6):801-25. PubMed ID: 19456274
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
    Roche D; Carniato D; Leriche C; Lepifre F; Christmann-Franck S; Graedler U; Charon C; Bozec S; Doare L; Schmidlin F; Lecomte M; Valeur E
    Bioorg Med Chem Lett; 2009 May; 19(10):2674-8. PubMed ID: 19395260
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Discovery of novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 by docking and pharmacophore modeling.
    Yang H; Dou W; Lou J; Leng Y; Shen J
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1340-5. PubMed ID: 18242087
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Alternative mechanism for anti-obesity effect of dehydroepiandrosterone: possible contribution of 11β-hydroxysteroid dehydrogenase type 1 inhibition in rodent adipose tissue.
    Tagawa N; Minamitani E; Yamaguchi Y; Kobayashi Y
    Steroids; 2011 Dec; 76(14):1546-53. PubMed ID: 21945397
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Pharmacological characterization of the selective 11β-hydroxysteroid dehydrogenase 1 inhibitor, BI 135585, a clinical candidate for the treatment of type 2 diabetes.
    Hamilton BS; Himmelsbach F; Nar H; Schuler-Metz A; Krosky P; Guo J; Guo R; Meng S; Zhao Y; Lala DS; Zhuang L; Claremon DA; McGeehan GM
    Eur J Pharmacol; 2015 Jan; 746():50-5. PubMed ID: 25445047
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The rise in expression and activity of 11β-HSD1 in human mesenchymal progenitor cells induces adipogenesis through increased local cortisol synthesis.
    Blaschke M; Koepp R; Streit F; Beismann J; Manthey G; Seitz MT; Kragl A; Siggelkow H
    J Steroid Biochem Mol Biol; 2021 Jun; 210():105850. PubMed ID: 33639236
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Synthesis and evaluation of colletoic acid core derivatives.
    Ling T; Gautam LN; Griffith E; Das S; Lang W; Shadrick WR; Shelat A; Lee R; Rivas F
    Eur J Med Chem; 2016 Mar; 110():126-32. PubMed ID: 26820555
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV.
    Boudon SM; Vuorinen A; Geotti-Bianchini P; Wandeler E; Kratschmar DV; Heidl M; Campiche R; Jackson E; Odermatt A
    PLoS One; 2017; 12(2):e0171079. PubMed ID: 28152550
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Novel non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Vicker N; Su X; Ganeshapillai D; Smith A; Purohit A; Reed MJ; Potter BV
    J Steroid Biochem Mol Biol; 2007 May; 104(3-5):123-9. PubMed ID: 17482805
    [TBL] [Abstract][Full Text] [Related]  

  • 50. 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
    Tomlinson JW; Walker EA; Bujalska IJ; Draper N; Lavery GG; Cooper MS; Hewison M; Stewart PM
    Endocr Rev; 2004 Oct; 25(5):831-66. PubMed ID: 15466942
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Phenylcyclobutyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
    Zhu Y; Olson SH; Graham D; Patel G; Hermanowski-Vosatka A; Mundt S; Shah K; Springer M; Thieringer R; Wright S; Xiao J; Zokian H; Dragovic J; Balkovec JM
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3412-6. PubMed ID: 18440812
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.
    Xiang J; Wan ZK; Li HQ; Ipek M; Binnun E; Nunez J; Chen L; McKew JC; Mansour TS; Xu X; Suri V; Tam M; Xing Y; Li X; Hahm S; Tobin J; Saiah E
    J Med Chem; 2008 Jul; 51(14):4068-71. PubMed ID: 18578516
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.
    Tomlinson JW; Sinha B; Bujalska I; Hewison M; Stewart PM
    J Clin Endocrinol Metab; 2002 Dec; 87(12):5630-5. PubMed ID: 12466364
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Effects of bile acids on rat hepatic microsomal type I 11beta-hydroxysteroid dehydrogenase.
    Maeda Y; Naganuma S; Niina I; Shinohara A; Koshimoto C; Kondo K; Chijiiwa K
    Steroids; 2010 Feb; 75(2):164-8. PubMed ID: 19948178
    [TBL] [Abstract][Full Text] [Related]  

  • 55. 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds.
    Blum A; Favia AD; Maser E
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):132-6. PubMed ID: 18822345
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11beta-hydroxysteroid dehydrogenase type 1) gene.
    Iwasaki Y; Takayasu S; Nishiyama M; Tsugita M; Taguchi T; Asai M; Yoshida M; Kambayashi M; Hashimoto K
    Mol Cell Endocrinol; 2008 Mar; 285(1-2):10-8. PubMed ID: 18313835
    [TBL] [Abstract][Full Text] [Related]  

  • 57. 11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action.
    Draper N; Stewart PM
    J Endocrinol; 2005 Aug; 186(2):251-71. PubMed ID: 16079253
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.
    Su X; Vicker N; Thomas MP; Pradaux-Caggiano F; Halem H; Culler MD; Potter BV
    ChemMedChem; 2011 Aug; 6(8):1439-51. PubMed ID: 21608132
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors.
    Su X; Pradaux-Caggiano F; Thomas MP; Szeto MW; Halem HA; Culler MD; Vicker N; Potter BV
    ChemMedChem; 2010 Jul; 5(7):1026-44. PubMed ID: 20486152
    [TBL] [Abstract][Full Text] [Related]  

  • 60. beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action.
    Xiang J; Ipek M; Suri V; Tam M; Xing Y; Huang N; Zhang Y; Tobin J; Mansour TS; McKew J
    Bioorg Med Chem; 2007 Jul; 15(13):4396-405. PubMed ID: 17490884
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.