These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

362 related articles for article (PubMed ID: 16181688)

  • 1. Identification of the optimal third generation antifolate against P. falciparum and P. vivax.
    Hunt SY; Detering C; Varani G; Jacobus DP; Schiehser GA; Shieh HM; Nevchas I; Terpinski J; Sibley CH
    Mol Biochem Parasitol; 2005 Dec; 144(2):198-205. PubMed ID: 16181688
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel Plasmodium falciparum expression system for assessing antifolate resistance caused by mutant P. vivax dihydrofolate reductase-thymidylate synthase.
    O'Neil MT; Korsinczky ML; Gresty KJ; Auliff A; Cheng Q
    J Infect Dis; 2007 Aug; 196(3):467-74. PubMed ID: 17597462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase.
    Fogel GB; Cheung M; Pittman E; Hecht D
    J Mol Graph Model; 2008 Apr; 26(7):1145-52. PubMed ID: 18037315
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antifolate screening using yeast expressing Plasmodium vivax dihydrofolate reductase and in vitro drug susceptibility assay for Plasmodium falciparum.
    Djapa LY; Basco LK; Zelikson R; Rosowsky A; Djaman JA; Yonkeu JN; Bolotin-Fukuhara M; Mazabraud A
    Mol Biochem Parasitol; 2007 Nov; 156(1):89-92. PubMed ID: 17727978
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Shape- and chemical feature-based 3D-pharmacophore model generation and virtual screening: identification of potential leads for P. falciparum DHFR enzyme inhibition.
    Adane L; Patel DS; Bharatam PV
    Chem Biol Drug Des; 2010 Jan; 75(1):115-26. PubMed ID: 19895504
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Similar trends of pyrimethamine resistance-associated mutations in Plasmodium vivax and P. falciparum.
    Alam MT; Bora H; Bharti PK; Saifi MA; Das MK; Dev V; Kumar A; Singh N; Dash AP; Das B; Wajihullah ; Sharma YD
    Antimicrob Agents Chemother; 2007 Mar; 51(3):857-63. PubMed ID: 17194833
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Plasmodium falciparum: kinetic interactions of WR99210 with pyrimethamine-sensitive and pyrimethamine-resistant dihydrofolate reductase.
    Hekmat-Nejad M; Rathod PK
    Exp Parasitol; 1997 Nov; 87(3):222-8. PubMed ID: 9371087
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Flexible diaminodihydrotriazine inhibitors of Plasmodium falciparum dihydrofolate reductase: Binding strengths, modes of binding and their antimalarial activities.
    Kamchonwongpaisan S; Charoensetakul N; Srisuwannaket C; Taweechai S; Rattanajak R; Vanichtanankul J; Vitsupakorn D; Arwon U; Thongpanchang C; Tarnchompoo B; Vilaivan T; Yuthavong Y
    Eur J Med Chem; 2020 Jun; 195():112263. PubMed ID: 32294614
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210.
    Hankins EG; Warhurst DC; Sibley CH
    Mol Biochem Parasitol; 2001 Sep; 117(1):91-102. PubMed ID: 11551635
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities.
    Kamchonwongpaisan S; Quarrell R; Charoensetakul N; Ponsinet R; Vilaivan T; Vanichtanankul J; Tarnchompoo B; Sirawaraporn W; Lowe G; Yuthavong Y
    J Med Chem; 2004 Jan; 47(3):673-80. PubMed ID: 14736247
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational drug design approach for overcoming drug resistance: application to pyrimethamine resistance in malaria.
    McKie JH; Douglas KT; Chan C; Roser SA; Yates R; Read M; Hyde JE; Dascombe MJ; Yuthavong Y; Sirawaraporn W
    J Med Chem; 1998 Apr; 41(9):1367-70. PubMed ID: 9554869
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel alleles of Plasmodium falciparum dhfr that confer resistance to chlorcycloguanil.
    Hunt SY; Rezvani BB; Sibley CH
    Mol Biochem Parasitol; 2005 Jan; 139(1):25-32. PubMed ID: 15610816
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular dynamics of interactions between rigid and flexible antifolates and dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium falciparum.
    Mokmak W; Chunsrivirot S; Hannongbua S; Yuthavong Y; Tongsima S; Kamchonwongpaisan S
    Chem Biol Drug Des; 2014 Oct; 84(4):450-61. PubMed ID: 24716467
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dihydrofolate reductase mutations in Plasmodium vivax from Indonesia and therapeutic response to sulfadoxine plus pyrimethamine.
    Hastings MD; Porter KM; Maguire JD; Susanti I; Kania W; Bangs MJ; Sibley CH; Baird JK
    J Infect Dis; 2004 Feb; 189(4):744-50. PubMed ID: 14767830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular epidemiology of malaria in Cameroon. XXVII. Clinical and parasitological response to sulfadoxine-pyrimethamine treatment and Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase alleles in Cameroonian children.
    Tahar R; Basco LK
    Acta Trop; 2007 Aug; 103(2):81-9. PubMed ID: 17640607
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defining the role of mutations in Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene using an episomal Plasmodium falciparum transfection system.
    Auliff AM; Adams JH; O'Neil MT; Cheng Q
    Antimicrob Agents Chemother; 2010 Sep; 54(9):3927-32. PubMed ID: 20566761
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional analysis of Plasmodium vivax dihydrofolate reductase-thymidylate synthase genes through stable transformation of Plasmodium falciparum.
    Auliff AM; Balu B; Chen N; O'Neil MT; Cheng Q; Adams JH
    PLoS One; 2012; 7(7):e40416. PubMed ID: 22792308
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Translational up-regulation of antifolate drug targets in the human malaria parasite Plasmodium falciparum upon challenge with inhibitors.
    Nirmalan N; Sims PF; Hyde JE
    Mol Biochem Parasitol; 2004 Jul; 136(1):63-70. PubMed ID: 15138068
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs.
    Auliff A; Wilson DW; Russell B; Gao Q; Chen N; Anh le N; Maguire J; Bell D; O'Neil MT; Cheng Q
    Am J Trop Med Hyg; 2006 Oct; 75(4):617-21. PubMed ID: 17038682
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyrimethamine analogs as strong inhibitors of double and quadruple mutants of dihydrofolate reductase in human malaria parasites.
    Sardarian A; Douglas KT; Read M; Sims PF; Hyde JE; Chitnumsub P; Sirawaraporn R; Sirawaraporn W
    Org Biomol Chem; 2003 Mar; 1(6):960-4. PubMed ID: 12929634
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.