BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 16182243)

  • 1. A fluorescence polarization-based interaction assay for hypoxia-inducible factor prolyl hydroxylases.
    Cho H; Park H; Yang EG
    Biochem Biophys Res Commun; 2005 Nov; 337(1):275-80. PubMed ID: 16182243
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
    Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
    J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIF-1alpha peptide derivatives with modifications at the hydroxyproline residue as activators of HIF-1alpha.
    Ahn DR; Kim SY; Lee MJ; Yang EG
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4403-5. PubMed ID: 19515556
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
    Jaakkola P; Mole DR; Tian YM; Wilson MI; Gielbert J; Gaskell SJ; von Kriegsheim A; Hebestreit HF; Mukherji M; Schofield CJ; Maxwell PH; Pugh CW; Ratcliffe PJ
    Science; 2001 Apr; 292(5516):468-72. PubMed ID: 11292861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.
    Callapina M; Zhou J; Schnitzer S; Metzen E; Lohr C; Deitmer JW; Brüne B
    Exp Cell Res; 2005 May; 306(1):274-84. PubMed ID: 15878351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
    Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
    EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases.
    Metzen E; Zhou J; Jelkmann W; Fandrey J; Brüne B
    Mol Biol Cell; 2003 Aug; 14(8):3470-81. PubMed ID: 12925778
    [TBL] [Abstract][Full Text] [Related]  

  • 9. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
    Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
    Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
    [TBL] [Abstract][Full Text] [Related]  

  • 10. von Hippel-Lindau β-domain-luciferase fusion protein as a bioluminescent hydroxyproline sensor for a hypoxia-inducible factor prolyl hydroxylase assay.
    Hong S; Yum S; Ha NC; Jung Y
    Anal Biochem; 2010 Dec; 407(2):220-5. PubMed ID: 20705044
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
    Chowdhury R; McDonough MA; Mecinović J; Loenarz C; Flashman E; Hewitson KS; Domene C; Schofield CJ
    Structure; 2009 Jul; 17(7):981-9. PubMed ID: 19604478
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proline hydroxylation and gene expression.
    Kaelin WG
    Annu Rev Biochem; 2005; 74():115-28. PubMed ID: 15952883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia-inducible factors in the first trimester human lung.
    Groenman F; Rutter M; Caniggia I; Tibboel D; Post M
    J Histochem Cytochem; 2007 Apr; 55(4):355-63. PubMed ID: 17189520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.
    Lee HY; Lee T; Lee N; Yang EG; Lee C; Lee J; Moon EY; Ha J; Park H
    Carcinogenesis; 2011 May; 32(5):703-12. PubMed ID: 21335603
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
    D'Angelo G; Duplan E; Boyer N; Vigne P; Frelin C
    J Biol Chem; 2003 Oct; 278(40):38183-7. PubMed ID: 12876291
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of hypoxia-induced transcription in normoxia.
    Hägg M; Wennström S
    Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
    Park YK; Ahn DR; Oh M; Lee T; Yang EG; Son M; Park H
    Mol Pharmacol; 2008 Jul; 74(1):236-45. PubMed ID: 18426857
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion.
    Demidenko ZN; Rapisarda A; Garayoa M; Giannakakou P; Melillo G; Blagosklonny MV
    Oncogene; 2005 Jul; 24(30):4829-38. PubMed ID: 15897903
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.
    Huang J; Zhao Q; Mooney SM; Lee FS
    J Biol Chem; 2002 Oct; 277(42):39792-800. PubMed ID: 12181324
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A nonradioactive 96-well plate assay for the detection of hypoxia-inducible factor prolyl hydroxylase activity.
    Oehme F; Jonghaus W; Narouz-Ott L; Huetter J; Flamme I
    Anal Biochem; 2004 Jul; 330(1):74-80. PubMed ID: 15183764
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.