BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 16182323)

  • 1. Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
    Gaida W; Klinder K; Arndt K; Weiser T
    Neuropharmacology; 2005 Dec; 49(8):1220-7. PubMed ID: 16182323
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Additive antinociceptive effects of the selective Nav1.8 blocker A-803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models.
    Joshi SK; Honore P; Hernandez G; Schmidt R; Gomtsyan A; Scanio M; Kort M; Jarvis MF
    J Pain; 2009 Mar; 10(3):306-15. PubMed ID: 19070548
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
    Jarvis MF; Honore P; Shieh CC; Chapman M; Joshi S; Zhang XF; Kort M; Carroll W; Marron B; Atkinson R; Thomas J; Liu D; Krambis M; Liu Y; McGaraughty S; Chu K; Roeloffs R; Zhong C; Mikusa JP; Hernandez G; Gauvin D; Wade C; Zhu C; Pai M; Scanio M; Shi L; Drizin I; Gregg R; Matulenko M; Hakeem A; Gross M; Johnson M; Marsh K; Wagoner PK; Sullivan JP; Faltynek CR; Krafte DS
    Proc Natl Acad Sci U S A; 2007 May; 104(20):8520-5. PubMed ID: 17483457
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia.
    Moon JY; Song S; Yoon SY; Roh DH; Kang SY; Park JH; Beitz AJ; Lee JH
    Anesth Analg; 2012 Jan; 114(1):215-23. PubMed ID: 22127815
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the effects of four Na+ channel analgesics on TTX-resistant Na+ currents in rat sensory neurons and recombinant Nav1.2 channels.
    Weiser T
    Neurosci Lett; 2006 Mar; 395(3):179-84. PubMed ID: 16293367
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.
    Kort ME; Drizin I; Gregg RJ; Scanio MJ; Shi L; Gross MF; Atkinson RN; Johnson MS; Pacofsky GJ; Thomas JB; Carroll WA; Krambis MJ; Liu D; Shieh CC; Zhang X; Hernandez G; Mikusa JP; Zhong C; Joshi S; Honore P; Roeloffs R; Marsh KC; Murray BP; Liu J; Werness S; Faltynek CR; Krafte DS; Jarvis MF; Chapman ML; Marron BE
    J Med Chem; 2008 Feb; 51(3):407-16. PubMed ID: 18176998
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats.
    Lindia JA; Köhler MG; Martin WJ; Abbadie C
    Pain; 2005 Sep; 117(1-2):145-53. PubMed ID: 16061326
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Future potential and status of selective sodium channel blockers for the treatment of pain.
    Priest BT
    Curr Opin Drug Discov Devel; 2009 Sep; 12(5):682-92. PubMed ID: 19736626
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of paclitaxel-induced A-fiber hypersensitization by gabapentin.
    Matsumoto M; Inoue M; Hald A; Xie W; Ueda H
    J Pharmacol Exp Ther; 2006 Aug; 318(2):735-40. PubMed ID: 16687474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury.
    Wu WP; Hao JX; Ongini E; Impagnatiello F; Presotto C; Wiesenfeld-Hallin Z; Xu XJ
    Br J Pharmacol; 2004 Jan; 141(1):65-74. PubMed ID: 14662726
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites.
    Leffler A; Reckzeh J; Nau C
    Eur J Pharmacol; 2010 Mar; 630(1-3):19-28. PubMed ID: 20044988
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain.
    Kolosov A; Goodchild CS; Cooke I
    Pain Med; 2010 Jan; 11(1):106-18. PubMed ID: 20447294
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Use-dependent block by lidocaine but not amitriptyline is more pronounced in tetrodotoxin (TTX)-Resistant Nav1.8 than in TTX-sensitive Na+ channels.
    Leffler A; Reiprich A; Mohapatra DP; Nau C
    J Pharmacol Exp Ther; 2007 Jan; 320(1):354-64. PubMed ID: 17005919
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
    Munro G; Storm A; Hansen MK; Dyhr H; Marcher L; Erichsen HK; Sheykhzade M
    Pharmacol Biochem Behav; 2012 May; 101(3):465-78. PubMed ID: 22366217
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antinociceptive effect of ambroxol in rats with neuropathic spinal cord injury pain.
    Hama AT; Plum AW; Sagen J
    Pharmacol Biochem Behav; 2010 Dec; 97(2):249-55. PubMed ID: 20732348
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gabapentin reduces allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing expression level of Nav1.7 and p-ERK1/2 in DRG neurons.
    Zhang JL; Yang JP; Zhang JR; Li RQ; Wang J; Jan JJ; Zhuang Q
    Brain Res; 2013 Feb; 1493():13-8. PubMed ID: 23183040
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential analgesic sensitivity of two distinct neuropathic pain models.
    Decosterd I; Allchorne A; Woolf CJ
    Anesth Analg; 2004 Aug; 99(2):457-63, table of contents. PubMed ID: 15271725
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of low-affinity NMDA receptor channel blockers in two rat models of chronic pain.
    Medvedev IO; Malyshkin AA; Belozertseva IV; Sukhotina IA; Sevostianova NY; Aliev K; Zvartau EE; Parsons CG; Danysz W; Bespalov AY
    Neuropharmacology; 2004 Aug; 47(2):175-83. PubMed ID: 15223296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats.
    Wodarski R; Clark AK; Grist J; Marchand F; Malcangio M
    Eur J Pain; 2009 Sep; 13(8):807-11. PubMed ID: 18977160
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intrathecal gabapentin does not act as a hyperpolarization-activated cyclic nucleotide-gated channel activator in the rat formalin test.
    Lin CF; Tsaur ML; Lin CS; Chen CC; Huang YJ; Cheng JK
    Eur J Anaesthesiol; 2009 Oct; 26(10):821-4. PubMed ID: 19322095
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.