BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 16192279)

  • 1. The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms.
    Fieulaine S; Juillan-Binard C; Serero A; Dardel F; Giglione C; Meinnel T; Ferrer JL
    J Biol Chem; 2005 Dec; 280(51):42315-24. PubMed ID: 16192279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
    Fieulaine S; Desmadril M; Meinnel T; Giglione C
    Acta Crystallogr D Biol Crystallogr; 2014 Feb; 70(Pt 2):242-52. PubMed ID: 24531459
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure and activity of human mitochondrial peptide deformylase, a novel cancer target.
    Escobar-Alvarez S; Goldgur Y; Yang G; Ouerfelli O; Li Y; Scheinberg DA
    J Mol Biol; 2009 Apr; 387(5):1211-28. PubMed ID: 19236878
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unique structural characteristics of peptide deformylase from pathogenic bacterium Leptospira interrogans.
    Zhou Z; Song X; Li Y; Gong W
    J Mol Biol; 2004 May; 339(1):207-15. PubMed ID: 15123432
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway.
    Serero A; Giglione C; Sardini A; Martinez-Sanz J; Meinnel T
    J Biol Chem; 2003 Dec; 278(52):52953-63. PubMed ID: 14532271
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insights into the substrate specificity of plant peptide deformylase, an essential enzyme with potential for the development of novel biotechnology applications in agriculture.
    Dirk LM; Schmidt JJ; Cai Y; Barnes JC; Hanger KM; Nayak NR; Williams MA; Grossman RB; Houtz RL; Rodgers DW
    Biochem J; 2008 Aug; 413(3):417-27. PubMed ID: 18412546
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinctive features of the two classes of eukaryotic peptide deformylases.
    Serero A; Giglione C; Meinnel T
    J Mol Biol; 2001 Dec; 314(4):695-708. PubMed ID: 11733990
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Toward More Selective Antibiotic Inhibitors: A Structural View of the Complexed Binding Pocket of
    Kirschner H; Heister N; Zouatom M; Zhou T; Hofmann E; Scherkenbeck J; Stoll R
    J Med Chem; 2024 Apr; 67(8):6384-6396. PubMed ID: 38574272
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of a human peptide deformylase: implications for antibacterial drug design.
    Nguyen KT; Hu X; Colton C; Chakrabarti R; Zhu MX; Pei D
    Biochemistry; 2003 Aug; 42(33):9952-8. PubMed ID: 12924944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The evolution of peptide deformylase as a target: contribution of biochemistry, genetics and genomics.
    Yuan Z; White RJ
    Biochem Pharmacol; 2006 Mar; 71(7):1042-7. PubMed ID: 16289392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species.
    Smith KJ; Petit CM; Aubart K; Smyth M; McManus E; Jones J; Fosberry A; Lewis C; Lonetto M; Christensen SB
    Protein Sci; 2003 Feb; 12(2):349-60. PubMed ID: 12538898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Docking studies of nickel-peptide deformylase (PDF) inhibitors: exploring the new binding pockets.
    Wang Q; Zhang D; Wang J; Cai Z; Xu W
    Biophys Chem; 2006 Jun; 122(1):43-9. PubMed ID: 16545516
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation.
    Grzela R; Nusbaum J; Fieulaine S; Lavecchia F; Bienvenut WV; Dian C; Meinnel T; Giglione C
    Sci Rep; 2017 Sep; 7(1):11041. PubMed ID: 28887476
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift.
    Zhou Z; Song X; Gong W
    J Biol Chem; 2005 Dec; 280(51):42391-6. PubMed ID: 16239225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of peptide deformylase2 from B. cereus.
    Park JK; Kim KH; Moon JH; Kim EE
    J Biochem Mol Biol; 2007 Nov; 40(6):1050-7. PubMed ID: 18047803
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the Ni(II) complex of Escherichia coli peptide deformylase and suggestions on deformylase activities depending on different metal(II) centres.
    Yen NT; Bogdanović X; Palm GJ; Kühl O; Hinrichs W
    J Biol Inorg Chem; 2010 Feb; 15(2):195-201. PubMed ID: 20112455
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing.
    Bingel-Erlenmeyer R; Kohler R; Kramer G; Sandikci A; Antolić S; Maier T; Schaffitzel C; Wiedmann B; Bukau B; Ban N
    Nature; 2008 Mar; 452(7183):108-11. PubMed ID: 18288106
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Peptide deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts.
    Grzela R; Nusbaum J; Fieulaine S; Lavecchia F; Desmadril M; Nhiri N; Van Dorsselaer A; Cianferani S; Jacquet E; Meinnel T; Giglione C
    Biochim Biophys Acta Proteins Proteom; 2018 Feb; 1866(2):348-355. PubMed ID: 29101077
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peptide deformylase: a new target in antibacterial, antimalarial and anticancer drug discovery.
    Sangshetti JN; Khan FA; Shinde DB
    Curr Med Chem; 2015; 22(2):214-36. PubMed ID: 25174923
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigation of zinc-containing peptide deformylase from Leptospira interrogans by X-ray absorption near-edge spectroscopy.
    Li S; Zhou Z; Chu W; Gong W; Benfatto M; Hu T; Xie Y; Xian D; Wu Z
    J Synchrotron Radiat; 2005 Jan; 12(Pt 1):111-4. PubMed ID: 15616374
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.