122 related articles for article (PubMed ID: 16192893)
1. Morphine via nitric oxide modulates beta-amyloid metabolism: a novel protective mechanism for Alzheimer's disease.
Pak T; Cadet P; Mantione KJ; Stefano GB
Med Sci Monit; 2005 Oct; 11(10):BR357-66. PubMed ID: 16192893
[TBL] [Abstract][Full Text] [Related]
2. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
Tanahashi H; Tabira T
Neurosci Lett; 2007 Nov; 428(2-3):103-8. PubMed ID: 17961921
[TBL] [Abstract][Full Text] [Related]
3. Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway.
Hook VY; Reisine TD
J Neurosci Res; 2003 Nov; 74(3):393-405. PubMed ID: 14598316
[TBL] [Abstract][Full Text] [Related]
4. Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?
Nawrot B
Acta Biochim Pol; 2004; 51(2):431-44. PubMed ID: 15218540
[TBL] [Abstract][Full Text] [Related]
5. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
[TBL] [Abstract][Full Text] [Related]
6. Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity.
Fu H; Li W; Luo J; Lee NT; Li M; Tsim KW; Pang Y; Youdim MB; Han Y
Biochem Biophys Res Commun; 2008 Feb; 366(3):631-6. PubMed ID: 18039469
[TBL] [Abstract][Full Text] [Related]
7. Fermented papaya preparation attenuates beta-amyloid precursor protein: beta-amyloid-mediated copper neurotoxicity in beta-amyloid precursor protein and beta-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells.
Zhang J; Mori A; Chen Q; Zhao B
Neuroscience; 2006 Nov; 143(1):63-72. PubMed ID: 16962711
[TBL] [Abstract][Full Text] [Related]
8. Down-regulation of muscarinic acetylcholine receptor M2 adversely affects the expression of Alzheimer's disease-relevant genes and proteins.
Zuchner T; Schliebs R; Perez-Polo JR
J Neurochem; 2005 Oct; 95(1):20-32. PubMed ID: 16181410
[TBL] [Abstract][Full Text] [Related]
9. Endogenous morphine signaling via nitric oxide regulates the expression of CYP2D6 and COMT: autocrine/paracrine feedback inhibition.
Mantione KJ; Cadet P; Zhu W; Kream RM; Sheehan M; Fricchione GL; Goumon Y; Esch T; Stefano GB
Addict Biol; 2008 Mar; 13(1):118-23. PubMed ID: 17573783
[TBL] [Abstract][Full Text] [Related]
10. Ibuprofen decreases cytokine-induced amyloid beta production in neuronal cells.
Blasko I; Apochal A; Boeck G; Hartmann T; Grubeck-Loebenstein B; Ransmayr G
Neurobiol Dis; 2001 Dec; 8(6):1094-101. PubMed ID: 11741404
[TBL] [Abstract][Full Text] [Related]
11. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease.
Holsinger RM; McLean CA; Beyreuther K; Masters CL; Evin G
Ann Neurol; 2002 Jun; 51(6):783-6. PubMed ID: 12112088
[TBL] [Abstract][Full Text] [Related]
12. Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease.
Liu K; Solano I; Mann D; Lemere C; Mercken M; Trojanowski JQ; Lee VM
Acta Neuropathol; 2006 Aug; 112(2):163-74. PubMed ID: 16865398
[TBL] [Abstract][Full Text] [Related]
13. Reduction of iron-regulated amyloid precursor protein and beta-amyloid peptide by (-)-epigallocatechin-3-gallate in cell cultures: implications for iron chelation in Alzheimer's disease.
Reznichenko L; Amit T; Zheng H; Avramovich-Tirosh Y; Youdim MB; Weinreb O; Mandel S
J Neurochem; 2006 Apr; 97(2):527-36. PubMed ID: 16539659
[TBL] [Abstract][Full Text] [Related]
14. Inhibiting gene expression of alpha3 nicotinic receptor in SH-SY5Y cells with the effects on APP metabolism and antioxidation in Alzheimer's disease.
Tang Z; An Y; Qi XL; Xiao Y; Shan KR; Guan ZZ
Neurochem Int; 2008 Nov; 53(5):112-7. PubMed ID: 18647633
[TBL] [Abstract][Full Text] [Related]
15. Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling.
Cho HJ; Jin SM; Youn HD; Huh K; Mook-Jung I
Aging Cell; 2008 Mar; 7(2):137-47. PubMed ID: 18081741
[TBL] [Abstract][Full Text] [Related]
16. Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins.
Schaeffer V; Patte-Mensah C; Eckert A; Mensah-Nyagan AG
J Neurobiol; 2006 Jul; 66(8):868-81. PubMed ID: 16673391
[TBL] [Abstract][Full Text] [Related]
17. Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression".
Lee HG; Perry G; Zhu X; Nunomura A; Smith MA
Free Radic Biol Med; 2006 Jul; 41(2):188-9. PubMed ID: 16814097
[No Abstract] [Full Text] [Related]
18. [Construction and identification of eukaryotic expression plasmid pcDNA3. 1-BACE and its transient expression in COS-7 cells].
Dong W; Gong H; Feng G
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2006 Apr; 20(4):423-6. PubMed ID: 16683448
[TBL] [Abstract][Full Text] [Related]
19. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
Johnston JA; Liu WW; Todd SA; Coulson DT; Murphy S; Irvine GB; Passmore AP
Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054
[TBL] [Abstract][Full Text] [Related]
20. Progress toward the discovery and development of efficacious BACE inhibitors.
Durham TB; Shepherd TA
Curr Opin Drug Discov Devel; 2006 Nov; 9(6):776-91. PubMed ID: 17117686
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]