114 related articles for article (PubMed ID: 16202593)
1. Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.
Rokosz LL; Huang CY; Reader JC; Stauffer TM; Chelsky D; Sigal NH; Ganguly AK; Baldwin JJ
Bioorg Med Chem Lett; 2005 Dec; 15(24):5537-43. PubMed ID: 16202593
[TBL] [Abstract][Full Text] [Related]
2. Guiding farnesyltransferase inhibitors from an ECLiPS library to the catalytic zinc.
Huang CY; Stauffer TM; Strickland CL; Reader JC; Huang H; Li G; Cooper AB; Doll RJ; Ganguly AK; Baldwin JJ; Rokosz LL
Bioorg Med Chem Lett; 2006 Feb; 16(3):507-11. PubMed ID: 16289818
[TBL] [Abstract][Full Text] [Related]
3. Antimalarial activity of methylpiperazinyl-substituted benzophenone-based farnesyltransferase inhibitors.
Kettler K; Wiesner J; Ortmann R; Dahse HM; Jomaa H; Schlitzer M
Pharmazie; 2006 Jan; 61(1):63-5. PubMed ID: 16454209
[No Abstract] [Full Text] [Related]
4. 3D-QSAR with the aid of pharmacophore search and docking-based alignments for farnesyltransferase inhibitors.
Vaidya M; Weigt M; Wiese M
Eur J Med Chem; 2009 Oct; 44(10):4070-82. PubMed ID: 19515462
[TBL] [Abstract][Full Text] [Related]
5. Understanding the antitumor activity of novel tricyclicpiperazinyl derivatives as farnesyltransferase inhibitors using CoMFA and CoMSIA.
Puntambekar DS; Giridhar R; Yadav MR
Eur J Med Chem; 2006 Nov; 41(11):1279-92. PubMed ID: 16919851
[TBL] [Abstract][Full Text] [Related]
6. New asymmetric synthesis of protein farnesyltransferase inhibitors via palladium-catalyzed cross-coupling reactions of 2-iodo-imidazoles.
Kerhervé J; Botuha C; Dubois J
Org Biomol Chem; 2009 May; 7(10):2214-22. PubMed ID: 19421463
[TBL] [Abstract][Full Text] [Related]
7. 3D-QSAR studies of farnesyltransferase inhibitors: a comparative molecular field analysis approach.
Puntambekar D; Giridhar R; Yadav MR
Bioorg Med Chem Lett; 2006 Apr; 16(7):1821-7. PubMed ID: 16455255
[TBL] [Abstract][Full Text] [Related]
8. 7-imidazolylalkanamido-1-carboxylalkylbenzo-diazepine, a novel series of farnesyltransferase inhibitors.
Wan SB; Chu FM; Guo ZR
Yao Xue Xue Bao; 2002 Jul; 37(7):516-21. PubMed ID: 12914320
[TBL] [Abstract][Full Text] [Related]
9. Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase.
Ohkanda J; Strickland CL; Blaskovich MA; Carrico D; Lockman JW; Vogt A; Bucher CJ; Sun J; Qian Y; Knowles D; Pusateri EE; Sebti SM; Hamilton AD
Org Biomol Chem; 2006 Feb; 4(3):482-92. PubMed ID: 16446806
[TBL] [Abstract][Full Text] [Related]
10. Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode.
Finlay MR; Acton DG; Andrews DM; Barker AJ; Dennis M; Fisher E; Graham MA; Green CP; Heaton DW; Karoutchi G; Loddick SA; Morgentin R; Roberts A; Tucker JA; Weir HM
Bioorg Med Chem Lett; 2008 Aug; 18(15):4442-6. PubMed ID: 18617397
[TBL] [Abstract][Full Text] [Related]
11. Exploring structure-activity relationships of tricyclic farnesyltransferase inhibitors using ECLiPS libraries.
Rokosz LL; Huang CY; Reader JC; Stauffer TM; Southwick EC; Li G; Chelsky D; Baldwin JJ
Comb Chem High Throughput Screen; 2006 Aug; 9(7):545-58. PubMed ID: 16925514
[TBL] [Abstract][Full Text] [Related]
12. Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.
Kohring K; Wiesner J; Altenkämper M; Sakowski J; Silber K; Hillebrecht A; Haebel P; Dahse HM; Ortmann R; Jomaa H; Klebe G; Schlitzer M
ChemMedChem; 2008 Aug; 3(8):1217-31. PubMed ID: 18470859
[TBL] [Abstract][Full Text] [Related]
13. Structurally simple farnesyltransferase inhibitors arrest the growth of malaria parasites.
Glenn MP; Chang SY; Hucke O; Verlinde CL; Rivas K; Hornéy C; Yokoyama K; Buckner FS; Pendyala PR; Chakrabarti D; Gelb M; Van Voorhis WC; Sebti SM; Hamilton AD
Angew Chem Int Ed Engl; 2005 Aug; 44(31):4903-6. PubMed ID: 16007716
[No Abstract] [Full Text] [Related]
14. Aryloxy substituted N-arylpiperazinones as dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
Bergman JM; Abrams MT; Davide JP; Greenberg IB; Robinson RG; Buser CA; Huber HE; Koblan KS; Kohl NE; Lobell RB; Graham SL; Hartman GD; Williams TM; Dinsmore CJ
Bioorg Med Chem Lett; 2001 Jun; 11(11):1411-5. PubMed ID: 11378366
[TBL] [Abstract][Full Text] [Related]
15. A novel class of highly potent, selective, and non-peptidic inhibitor of Ras farnesyltransferase (FTase).
Lee H; Lee J; Lee S; Shin Y; Jung W; Kim JH; Park K; Kim K; Cho HS; Ro S; Lee S; Jeong SW; Choi T; Chung HH; Koh JS
Bioorg Med Chem Lett; 2001 Dec; 11(23):3069-72. PubMed ID: 11714612
[TBL] [Abstract][Full Text] [Related]
16. Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase.
Bolchi C; Pallavicini M; Bernini SK; Chiodini G; Corsini A; Ferri N; Fumagalli L; Straniero V; Valoti E
Bioorg Med Chem Lett; 2011 Sep; 21(18):5408-12. PubMed ID: 21802946
[TBL] [Abstract][Full Text] [Related]
17. Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase.
Dinsmore CJ; Bergman JM; Wei DD; Zartman CB; Davide JP; Greenberg IB; Liu D; O'Neill TJ; Gibbs JB; Koblan KS; Kohl NE; Lobell RB; Chen IW; McLoughlin DA; Olah TV; Graham SL; Hartman GD; Williams TM
Bioorg Med Chem Lett; 2001 Feb; 11(4):537-40. PubMed ID: 11229765
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors.
Abuhaie CM; Ghinet A; Farce A; Dubois J; Rigo B; Bîcu E
Bioorg Med Chem Lett; 2013 Nov; 23(21):5887-92. PubMed ID: 24054122
[TBL] [Abstract][Full Text] [Related]
19. Pharmacophore mapping of diverse classes of farnesyltransferase inhibitors.
Equbal T; Silakari O; Rambabu G; Ravikumar M
Bioorg Med Chem Lett; 2007 Mar; 17(6):1594-600. PubMed ID: 17236767
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of potential bisubstrate inhibitors of protein farnesyltransferase. Design and synthesis of functionalized imidazoles.
de Figueiredo RM; Coudray L; Dubois J
Org Biomol Chem; 2007 Oct; 5(20):3299-309. PubMed ID: 17912382
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
