138 related articles for article (PubMed ID: 16203134)
1. Preparation of human Melanocortin-4 receptor agonist libraries: linear peptides X-Y-DPhe7-Arg8-Trp(or 2-Nal)9-Z-NH2.
Cheung AW; Qi L; Gore V; Chu XJ; Bartkovitz D; Kurylko G; Swistok J; Danho W; Chen L; Yagaloff K
Bioorg Med Chem Lett; 2005 Dec; 15(24):5504-8. PubMed ID: 16203134
[TBL] [Abstract][Full Text] [Related]
2. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
Haskell-Luevano C; Hendrata S; North C; Sawyer TK; Hadley ME; Hruby VJ; Dickinson C; Gantz I
J Med Chem; 1997 Jul; 40(14):2133-9. PubMed ID: 9216831
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationship of linear peptide Bu-His6-DPhe7-Arg8-Trp9-Gly10-NH2 at the human melanocortin-1 and -4 receptors: DPhe7 and Trp9 substitution.
Danho W; Swistok J; Cheung AW; Kurylko G; Franco L; Chu XJ; Chen L; Yagaloff K
Bioorg Med Chem Lett; 2003 Feb; 13(4):649-52. PubMed ID: 12639550
[TBL] [Abstract][Full Text] [Related]
4. Structure-activity relationships of the unique and potent agouti-related protein (AGRP)-melanocortin chimeric Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 peptide template.
Wilczynski A; Wilson KR; Scott JW; Edison AS; Haskell-Luevano C
J Med Chem; 2005 Apr; 48(8):3060-75. PubMed ID: 15828845
[TBL] [Abstract][Full Text] [Related]
5. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
[TBL] [Abstract][Full Text] [Related]
6. Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues.
Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ
J Med Chem; 2003 Nov; 46(23):4965-73. PubMed ID: 14584947
[TBL] [Abstract][Full Text] [Related]
7. Discovery of 1-amino-4-phenylcyclohexane-1-carboxylic acid and its influence on agonist selectivity between human melanocortin-4 and -1 receptors in linear pentapeptides.
Chu XJ; Bartkovitz D; Danho W; Swistok J; Cheung AW; Kurylko G; Rowan K; Yeon M; Franco L; Qi L; Chen L; Yagaloff K
Bioorg Med Chem Lett; 2005 Nov; 15(22):4910-4. PubMed ID: 16169218
[TBL] [Abstract][Full Text] [Related]
8. End-capping of the modified melanocortin tetrapeptide (p-Cl)Phe-D-Phe-Arg-Trp-NH2 as a route to hMC4R agonists.
Koikov LN; Ebetino FH; Hayes JC; Cross-Doersen D; Knittel JJ
Bioorg Med Chem Lett; 2004 Oct; 14(19):4839-42. PubMed ID: 15341935
[TBL] [Abstract][Full Text] [Related]
9. Peptide and small molecules rescue the functional activity and agonist potency of dysfunctional human melanocortin-4 receptor polymorphisms.
Xiang Z; Pogozheva ID; Sorenson NB; Wilczynski AM; Holder JR; Litherland SA; Millard WJ; Mosberg HI; Haskell-Luevano C
Biochemistry; 2007 Jul; 46(28):8273-87. PubMed ID: 17590021
[TBL] [Abstract][Full Text] [Related]
10. N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes.
Todorovic A; Holder JR; Bauzo RM; Scott JW; Kavanagh R; Abdel-Malek Z; Haskell-Luevano C
J Med Chem; 2005 May; 48(9):3328-36. PubMed ID: 15857138
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH(2) at the human melanocortin-1 and -4 receptors: histidine substitution.
Cheung AW; Danho W; Swistok J; Qi L; Kurylko G; Rowan K; Yeon M; Franco L; Chu XJ; Chen L; Yagaloff K
Bioorg Med Chem Lett; 2003 Jan; 13(1):133-7. PubMed ID: 12467633
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH(2) at the human melanocortin-1 and -4 receptors: arginine substitution.
Cheung AW; Danho W; Swistok J; Qi L; Kurylko G; Franco L; Yagaloff K; Chen L
Bioorg Med Chem Lett; 2002 Sep; 12(17):2407-10. PubMed ID: 12161144
[TBL] [Abstract][Full Text] [Related]
13. Aza-scanning of the potent melanocortin receptor agonist Ac-His-D-Phe-Arg-Trp-NH.
Boeglin D; Xiang Z; Sorenson NB; Wood MS; Haskell-Luevano C; Lubell WD
Chem Biol Drug Des; 2006 Apr; 67(4):275-83. PubMed ID: 16629825
[TBL] [Abstract][Full Text] [Related]
14. Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist.
Han G; Quillan JM; Carlson K; Sadée W; Hruby VJ
J Med Chem; 2003 Feb; 46(5):810-9. PubMed ID: 12593660
[TBL] [Abstract][Full Text] [Related]
15. Accelerating sensory recovery after sciatic nerve crush: non-selective versus melanocortin MC4 receptor-selective peptides.
Nijenhuis WA; Wanders N; Kruijtzer JA; Liskamp RM; Gispen WH; Adan RA
Eur J Pharmacol; 2004 Jul; 495(2-3):145-52. PubMed ID: 15249163
[TBL] [Abstract][Full Text] [Related]
16. Analogs of sub-nanomolar hMC1R agonist LK-184 [Ph(CH2)3CO-His-D-Phe-Arg-Trp-NH2]. An additional binding site within the human melanocortin receptor 1?
Koikov LN; Ebetino FH; Solinsky MG; Cross-Doersen D; Knittel JJ
Bioorg Med Chem Lett; 2004 Aug; 14(15):3997-4000. PubMed ID: 15225714
[TBL] [Abstract][Full Text] [Related]
17. A predictive pharmacophore model of human melanocortin-4 receptor as derived from the solution structures of cyclic peptides.
Sun H; Greeley DN; Chu XJ; Cheung A; Danho W; Swistok J; Wang Y; Zhao C; Chen L; Fry DC
Bioorg Med Chem; 2004 May; 12(10):2671-7. PubMed ID: 15110848
[TBL] [Abstract][Full Text] [Related]
18. Functional characterization of the modified melanocortin peptides responsible for ligand selectivity at the human melanocortin receptors.
Chen M; Georgeson KE; Harmon CM; Haskell-Luevano C; Yang Y
Peptides; 2006 Nov; 27(11):2836-45. PubMed ID: 16730390
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat.
Ye Z; MacNeil T; Weinberg DH; Kalyani RN; Tang R; Strack AM; Murphy BA; Mosley RT; Euan MacIntyre D; Van der Ploeg LH; Patchett AA; Wyvratt MJ; Nargund RP
Peptides; 2005 Oct; 26(10):2017-25. PubMed ID: 15993513
[TBL] [Abstract][Full Text] [Related]
20. Potent and selective agonists of alpha-melanotropin (alphaMSH) action at human melanocortin receptor 5; linear analogs of alpha-melanotropin.
Bednarek MA; MacNeil T; Tang R; Fong TM; Cabello MA; Maroto M; Teran A
Peptides; 2007 May; 28(5):1020-8. PubMed ID: 17376561
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]