BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

419 related articles for article (PubMed ID: 16204079)

  • 1. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity.
    Kong D; Park EJ; Stephen AG; Calvani M; Cardellina JH; Monks A; Fisher RJ; Shoemaker RH; Melillo G
    Cancer Res; 2005 Oct; 65(19):9047-55. PubMed ID: 16204079
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
    Rapisarda A; Uranchimeg B; Scudiero DA; Selby M; Sausville EA; Shoemaker RH; Melillo G
    Cancer Res; 2002 Aug; 62(15):4316-24. PubMed ID: 12154035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the PAS-A domain of HIF-1alpha for development of small molecule inhibitors of HIF-1.
    Park EJ; Kong D; Fisher R; Cardellina J; Shoemaker RH; Melillo G
    Cell Cycle; 2006 Aug; 5(16):1847-53. PubMed ID: 16861921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions.
    Vlaminck B; Toffoli S; Ghislain B; Demazy C; Raes M; Michiels C
    FEBS J; 2007 Nov; 274(21):5533-42. PubMed ID: 17916190
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
    Song X; Yao J; Wang F; Zhou M; Zhou Y; Wang H; Wei L; Zhao L; Li Z; Lu N; Guo Q
    Toxicol Appl Pharmacol; 2013 Sep; 271(2):144-55. PubMed ID: 23707765
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
    Chau NM; Rogers P; Aherne W; Carroll V; Collins I; McDonald E; Workman P; Ashcroft M
    Cancer Res; 2005 Jun; 65(11):4918-28. PubMed ID: 15930314
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding.
    Jones DT; Harris AL
    Mol Cancer Ther; 2006 Sep; 5(9):2193-202. PubMed ID: 16985052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Estrogen receptor beta inhibits transcriptional activity of hypoxia inducible factor-1 through the downregulation of arylhydrocarbon receptor nuclear translocator.
    Lim W; Park Y; Cho J; Park C; Park J; Park YK; Park H; Lee Y
    Breast Cancer Res; 2011 Mar; 13(2):R32. PubMed ID: 21435239
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.
    Tan C; de Noronha RG; Roecker AJ; Pyrzynska B; Khwaja F; Zhang Z; Zhang H; Teng Q; Nicholson AC; Giannakakou P; Zhou W; Olson JJ; Pereira MM; Nicolaou KC; Van Meir EG
    Cancer Res; 2005 Jan; 65(2):605-12. PubMed ID: 15695405
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.
    Creighton-Gutteridge M; Cardellina JH; Stephen AG; Rapisarda A; Uranchimeg B; Hite K; Denny WA; Shoemaker RH; Melillo G
    Clin Cancer Res; 2007 Feb; 13(3):1010-8. PubMed ID: 17289897
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Coordinate activation of HIF-1 and NF-kappaB DNA binding and COX-2 and VEGF expression in retinal cells by hypoxia.
    Lukiw WJ; Ottlecz A; Lambrou G; Grueninger M; Finley J; Thompson HW; Bazan NG
    Invest Ophthalmol Vis Sci; 2003 Oct; 44(10):4163-70. PubMed ID: 14507857
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.
    Takeda N; Maemura K; Imai Y; Harada T; Kawanami D; Nojiri T; Manabe I; Nagai R
    Circ Res; 2004 Jul; 95(2):146-53. PubMed ID: 15192019
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor-alpha expression but decrease functional transcriptional activity, DNA binding, and degradation.
    Jones DT; Pugh CW; Wigfield S; Stevens MF; Harris AL
    Clin Cancer Res; 2006 Sep; 12(18):5384-94. PubMed ID: 17000671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms.
    Rong Y; Hu F; Huang R; Mackman N; Horowitz JM; Jensen RL; Durden DL; Van Meir EG; Brat DJ
    Cancer Res; 2006 Jul; 66(14):7067-74. PubMed ID: 16849552
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1.
    Forsythe JA; Jiang BH; Iyer NV; Agani F; Leung SW; Koos RD; Semenza GL
    Mol Cell Biol; 1996 Sep; 16(9):4604-13. PubMed ID: 8756616
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Physical and functional interactions between Runx2 and HIF-1α induce vascular endothelial growth factor gene expression.
    Kwon TG; Zhao X; Yang Q; Li Y; Ge C; Zhao G; Franceschi RT
    J Cell Biochem; 2011 Dec; 112(12):3582-93. PubMed ID: 21793044
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae.
    Rajakumar A; Brandon HM; Daftary A; Ness R; Conrad KP
    Placenta; 2004 Nov; 25(10):763-9. PubMed ID: 15451190
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.
    Wiesener MS; Turley H; Allen WE; Willam C; Eckardt KU; Talks KL; Wood SM; Gatter KC; Harris AL; Pugh CW; Ratcliffe PJ; Maxwell PH
    Blood; 1998 Oct; 92(7):2260-8. PubMed ID: 9746763
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hypoxia-inducible factor 1 transactivates the human leptin gene promoter.
    Grosfeld A; Andre J; Hauguel-De Mouzon S; Berra E; Pouyssegur J; Guerre-Millo M
    J Biol Chem; 2002 Nov; 277(45):42953-7. PubMed ID: 12215445
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.