136 related articles for article (PubMed ID: 16204993)
1. Novel N-(4-Piperidinyl)benzamide antimalarials with mammalian protein farnesyltransferase inhibitory activity.
Ryckebusch A; Gilleron P; Millet R; Houssin R; Lemoine A; Pommery N; Grellier P; Sergheraert C; Hénichart JP
Chem Pharm Bull (Tokyo); 2005 Oct; 53(10):1324-6. PubMed ID: 16204993
[TBL] [Abstract][Full Text] [Related]
2. Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity.
Ohkanda J; Lockman JW; Yokoyama K; Gelb MH; Croft SL; Kendrick H; Harrell MI; Feagin JE; Blaskovich MA; Sebti SM; Hamilton AD
Bioorg Med Chem Lett; 2001 Mar; 11(6):761-4. PubMed ID: 11277514
[TBL] [Abstract][Full Text] [Related]
3. 2-Oxotetrahydroquinoline-based antimalarials with high potency and metabolic stability.
Bulbule VJ; Rivas K; Verlinde CL; Van Voorhis WC; Gelb MH
J Med Chem; 2008 Feb; 51(3):384-7. PubMed ID: 18198825
[TBL] [Abstract][Full Text] [Related]
4. Identification and SAR Evaluation of Hemozoin-Inhibiting Benzamides Active against Plasmodium falciparum.
Wicht KJ; Combrinck JM; Smith PJ; Hunter R; Egan TJ
J Med Chem; 2016 Jul; 59(13):6512-30. PubMed ID: 27299916
[TBL] [Abstract][Full Text] [Related]
5. Protein farnesyltransferase inhibitors exhibit potent antimalarial activity.
Nallan L; Bauer KD; Bendale P; Rivas K; Yokoyama K; Hornéy CP; Pendyala PR; Floyd D; Lombardo LJ; Williams DK; Hamilton A; Sebti S; Windsor WT; Weber PC; Buckner FS; Chakrabarti D; Gelb MH; Van Voorhis WC
J Med Chem; 2005 Jun; 48(11):3704-13. PubMed ID: 15916422
[TBL] [Abstract][Full Text] [Related]
6. A Review on Plasmodium falciparum-Protein Farnesyltransferase Inhibitors as Antimalarial Drug Targets.
Sharma K
Curr Drug Targets; 2017; 18(14):1676-1686. PubMed ID: 27557819
[TBL] [Abstract][Full Text] [Related]
7. Cell-based optimization of novel benzamides as potential antimalarial leads.
Wu T; Nagle A; Sakata T; Henson K; Borboa R; Chen Z; Kuhen K; Plouffe D; Winzeler E; Adrian F; Tuntland T; Chang J; Simerson S; Howard S; Ek J; Isbell J; Deng X; Gray NS; Tully DC; Chatterjee AK
Bioorg Med Chem Lett; 2009 Dec; 19(24):6970-4. PubMed ID: 19879133
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and structure-activity relationship of disubstituted benzamides as a novel class of antimalarial agents.
Mitachi K; Salinas YG; Connelly M; Jensen N; Ling T; Rivas F
Bioorg Med Chem Lett; 2012 Jul; 22(14):4536-9. PubMed ID: 22727641
[TBL] [Abstract][Full Text] [Related]
9. Novel lead structures for antimalarial farnesyltransferase inhibitors.
Kettler K; Sakowski J; Wiesner J; Ortmann R; Jomaa H; Schlitzer M
Pharmazie; 2005 May; 60(5):323-7. PubMed ID: 15918578
[TBL] [Abstract][Full Text] [Related]
10. 2-(Arylpropionylamino)- and 2-(arylacryloylamino)benzophenones: farnesyltransferase inhibition and antimalarial activity.
Fucik K; Kettler K; Wiesner J; Ortmann R; Unterreitmeier D; Krauss J; Bracher F; Jomaa H; Schlitzer M
Pharmazie; 2004 Oct; 59(10):744-52. PubMed ID: 15544051
[TBL] [Abstract][Full Text] [Related]
11. Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials.
Opsenica I; Opsenica D; Smith KS; Milhous WK; Solaja BA
J Med Chem; 2008 Apr; 51(7):2261-6. PubMed ID: 18330976
[TBL] [Abstract][Full Text] [Related]
12. The synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer and antimalarial agents.
Johnson-Ajinwo OR; Ullah I; Mbye H; Richardson A; Horrocks P; Li WW
Bioorg Med Chem Lett; 2018 Apr; 28(7):1219-1222. PubMed ID: 29519737
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and anti-malarial activities of synthetic analogs of biselyngbyolide B, a Ca
Sato E; Morita M; Ogawa H; Iwatsuki M; Hokari R; Ishiyama A; Ōmura S; Iwasaki A; Suenaga K
Bioorg Med Chem Lett; 2018 Feb; 28(3):298-301. PubMed ID: 29292225
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and in vitro evaluation of hydrazinyl phthalazines against malaria parasite, Plasmodium falciparum.
Subramanian G; Babu Rajeev CP; Mohan CD; Sinha A; Chu TTT; Anusha S; Ximei H; Fuchs JE; Bender A; Rangappa KS; Chandramohanadas R; Basappa
Bioorg Med Chem Lett; 2016 Jul; 26(14):3300-3306. PubMed ID: 27261180
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of novel bicyclic beta-lactams as potential antimalarials.
Nivsarkar M; Thavaselvam D; Prasanna S; Sharma M; Kaushik MP
Bioorg Med Chem Lett; 2005 Mar; 15(5):1371-3. PubMed ID: 15713389
[TBL] [Abstract][Full Text] [Related]
16. Application of multicomponent reactions to antimalarial drug discovery. Part 3: discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro.
Musonda CC; Little S; Yardley V; Chibale K
Bioorg Med Chem Lett; 2007 Sep; 17(17):4733-6. PubMed ID: 17644333
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of A/B-ring partial analogs of bruceantin as potential antimalarial agents.
Guo Z; Vangapandu S; Nimrod A; Walker LA; Sindelar RD
Med Chem; 2005 Jan; 1(1):3-11. PubMed ID: 16789880
[TBL] [Abstract][Full Text] [Related]
18. Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.
Kohring K; Wiesner J; Altenkämper M; Sakowski J; Silber K; Hillebrecht A; Haebel P; Dahse HM; Ortmann R; Jomaa H; Klebe G; Schlitzer M
ChemMedChem; 2008 Aug; 3(8):1217-31. PubMed ID: 18470859
[TBL] [Abstract][Full Text] [Related]
19. Non-thiol farnesyltransferase inhibitors: N-(4-aminoacylamino-3-benzoylphenyl)-3-[5-(4-nitrophenyl)-2 furyl]acrylic acid amides and their antimalarial activity.
Kettler K; Wiesner J; Silber K; Haebel P; Ortmann R; Sattler I; Dahse HM; Jomaa H; Klebe G; Schlitzer M
Eur J Med Chem; 2005 Jan; 40(1):93-101. PubMed ID: 15642414
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates.
Lourens AC; Gravestock D; van Zyl RL; Hoppe HC; Kolesnikova N; Taweechai S; Yuthavong Y; Kamchonwongpaisan S; Rousseau AL
Org Biomol Chem; 2016 Aug; 14(33):7899-911. PubMed ID: 27477595
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
