198 related articles for article (PubMed ID: 16207145)
1. Pharmacogenetics of folate-related drug targets in cancer treatment.
Robien K; Boynton A; Ulrich CM
Pharmacogenomics; 2005 Oct; 6(7):673-89. PubMed ID: 16207145
[TBL] [Abstract][Full Text] [Related]
2. Pharmacogenetics and folate metabolism -- a promising direction.
Ulrich CM; Robien K; Sparks R
Pharmacogenomics; 2002 May; 3(3):299-313. PubMed ID: 12052139
[TBL] [Abstract][Full Text] [Related]
3. Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis.
Dervieux T; Greenstein N; Kremer J
Arthritis Rheum; 2006 Oct; 54(10):3095-103. PubMed ID: 17009228
[TBL] [Abstract][Full Text] [Related]
4. Folate and antifolate pharmacology.
Kamen B
Semin Oncol; 1997 Oct; 24(5 Suppl 18):S18-30-S18-39. PubMed ID: 9420019
[TBL] [Abstract][Full Text] [Related]
5. Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance.
Taddia L; D'Arca D; Ferrari S; Marraccini C; Severi L; Ponterini G; Assaraf YG; Marverti G; Costi MP
Drug Resist Updat; 2015 Nov; 23():20-54. PubMed ID: 26690339
[TBL] [Abstract][Full Text] [Related]
6. How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy.
Jennings BA; Willis G
Cancer Lett; 2015 Jan; 356(2 Pt A):224-30. PubMed ID: 24614284
[TBL] [Abstract][Full Text] [Related]
7. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors.
Jansen G; Schornagel JH; Westerhof GR; Rijksen G; Newell DR; Jackman AL
Cancer Res; 1990 Dec; 50(23):7544-8. PubMed ID: 2253202
[TBL] [Abstract][Full Text] [Related]
8. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
van der Wilt CL; Backus HH; Smid K; Comijn L; Veerman G; Wouters D; Voorn DA; Priest DG; Bunni MA; Mitchell F; Jackman AL; Jansen G; Peters GJ
Cancer Res; 2001 May; 61(9):3675-81. PubMed ID: 11325838
[TBL] [Abstract][Full Text] [Related]
9. C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation.
De Mattia E; Toffoli G
Eur J Cancer; 2009 May; 45(8):1333-51. PubMed ID: 19144510
[TBL] [Abstract][Full Text] [Related]
10. Role of the MTHFR polymorphisms in cancer risk modification and treatment.
Kim YI
Future Oncol; 2009 May; 5(4):523-42. PubMed ID: 19450180
[TBL] [Abstract][Full Text] [Related]
11. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
12. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.
Westerhof GR; Schornagel JH; Kathmann I; Jackman AL; Rosowsky A; Forsch RA; Hynes JB; Boyle FT; Peters GJ; Pinedo HM
Mol Pharmacol; 1995 Sep; 48(3):459-71. PubMed ID: 7565626
[TBL] [Abstract][Full Text] [Related]
13. Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance.
Gonen N; Assaraf YG
Drug Resist Updat; 2012 Aug; 15(4):183-210. PubMed ID: 22921318
[TBL] [Abstract][Full Text] [Related]
14. Molecular basis of antifolate resistance.
Assaraf YG
Cancer Metastasis Rev; 2007 Mar; 26(1):153-81. PubMed ID: 17333344
[TBL] [Abstract][Full Text] [Related]
15. Association of methotrexate effects and single-nucleotide polymorphisms in the folate pathway in rheumatoid arthritis: comment on the article by Wessels et al.
Ranganathan P
Arthritis Rheum; 2006 Oct; 54(10):3372; author reply 3372-3. PubMed ID: 17009311
[No Abstract] [Full Text] [Related]
16. Current approaches for TYMS polymorphisms and their importance in molecular epidemiology and pharmacogenetics.
Lima A; Azevedo R; Sousa H; Seabra V; Medeiros R
Pharmacogenomics; 2013 Aug; 14(11):1337-51. PubMed ID: 23930679
[TBL] [Abstract][Full Text] [Related]
17. Thymidylate synthase structure, function and implication in drug discovery.
Costi MP; Ferrari S; Venturelli A; Calò S; Tondi D; Barlocco D
Curr Med Chem; 2005; 12(19):2241-58. PubMed ID: 16178783
[TBL] [Abstract][Full Text] [Related]
18. Therapeutic strategies targeting proteins that regulate folate and reduced folate transport.
Trippett TM; Bertino JR
J Chemother; 1999 Feb; 11(1):3-10. PubMed ID: 10078775
[TBL] [Abstract][Full Text] [Related]
19. An overview of folate metabolism: features relevant to the action and toxicities of antifolate anticancer agents.
Calvert H
Semin Oncol; 1999 Apr; 26(2 Suppl 6):3-10. PubMed ID: 10598549
[No Abstract] [Full Text] [Related]
20. Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia.
Costea I; Moghrabi A; Laverdiere C; Graziani A; Krajinovic M
Haematologica; 2006 Aug; 91(8):1113-6. PubMed ID: 16870553
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
