BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 16208494)

  • 1. Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand.
    Najajreh Y; Kasparkova J; Marini V; Gibson D; Brabec V
    J Biol Inorg Chem; 2005 Nov; 10(7):722-31. PubMed ID: 16208494
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.
    Kasparkova J; Marini V; Najajreh Y; Gibson D; Brabec V
    Biochemistry; 2003 May; 42(20):6321-32. PubMed ID: 12755637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action.
    Kasparkova J; Novakova O; Marini V; Najajreh Y; Gibson D; Perez JM; Brabec V
    J Biol Chem; 2003 Nov; 278(48):47516-25. PubMed ID: 12970368
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)].
    Brabec V; Christofis P; Slámová M; Kostrhunová H; Nováková O; Najajreh Y; Gibson D; Kaspárková J
    Biochem Pharmacol; 2007 Jun; 73(12):1887-900. PubMed ID: 17400194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.
    Kasparkova J; Novakova O; Farrell N; Brabec V
    Biochemistry; 2003 Jan; 42(3):792-800. PubMed ID: 12534292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural characterization, DNA interactions, and cytotoxicity of new transplatin analogues containing one aliphatic and one planar heterocyclic amine ligand.
    Ramos-Lima FJ; Vrána O; Quiroga AG; Navarro-Ranninger C; Halámiková A; Rybnícková H; Hejmalová L; Brabec V
    J Med Chem; 2006 Apr; 49(8):2640-51. PubMed ID: 16610807
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel apoptosis-inducing trans-platinum piperidine derivatives: synthesis and biological characterization.
    Khazanov E; Barenholz Y; Gibson D; Najajreh Y
    J Med Chem; 2002 Nov; 45(24):5196-204. PubMed ID: 12431047
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The induction of lysis in lysogenic strains of Escherichia coli by a new antitumor transplatin derivative and its DNA interactions.
    Brabec V; Pracharova J; Novakova O; Gibson D; Kasparkova J
    Dalton Trans; 2015 Feb; 44(8):3573-82. PubMed ID: 25406573
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of a piperidine ligand on DNA modification by antitumor cisplatin analogues.
    Kasparkova J; Novakova O; Najajreh Y; Gibson D; Perez JM; Brabec V
    Chem Res Toxicol; 2003 Nov; 16(11):1424-32. PubMed ID: 14615968
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of trans geometry in bifunctional mononuclear platinum complexes by a non-bulky methylamine ligand.
    Frybortova M; Novakova O; Stepankova J; Novohradsky V; Gibson D; Kasparkova J; Brabec V
    J Inorg Biochem; 2013 Sep; 126():46-54. PubMed ID: 23770803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA interactions of antitumor trans-[PtCl2(NH3)(quinoline)].
    Zákovská A; Nováková O; Balcarová Z; Bierbach U; Farrell N; Brabec V
    Eur J Biochem; 1998 Jun; 254(3):547-57. PubMed ID: 9688265
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA modifications by antitumor trans-[PtCl2(E-iminoether)2].
    Zaludová R; Zákovská A; Kaspárkova J; Balcarová Z; Vrána O; Coluccia M; Natile G; Brabec V
    Mol Pharmacol; 1997 Sep; 52(3):354-61. PubMed ID: 9281596
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA-protein cross-linking by trans-[PtCl(2)(E-iminoether)(2)]. A concept for activation of the trans geometry in platinum antitumor complexes.
    Novakova O; Kasparkova J; Malina J; Natile G; Brabec V
    Nucleic Acids Res; 2003 Nov; 31(22):6450-60. PubMed ID: 14602903
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The stability of DNA intrastrand cross-links of antitumor transplatin derivative containing non-bulky methylamine ligands.
    Frybortova M; Novakova O; Brabec V
    J Biol Inorg Chem; 2014 Oct; 19(7):1203-8. PubMed ID: 24986778
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)].
    Marini V; Christofis P; Novakova O; Kasparkova J; Farrell N; Brabec V
    Nucleic Acids Res; 2005; 33(18):5819-28. PubMed ID: 16237123
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.
    Zhao Y; Woods JA; Farrer NJ; Robinson KS; Pracharova J; Kasparkova J; Novakova O; Li H; Salassa L; Pizarro AM; Clarkson GJ; Song L; Brabec V; Sadler PJ
    Chemistry; 2013 Jul; 19(29):9578-91. PubMed ID: 23733242
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.
    Prokop R; Kasparkova J; Novakova O; Marini V; Pizarro AM; Navarro-Ranninger C; Brabec V
    Biochem Pharmacol; 2004 Mar; 67(6):1097-109. PubMed ID: 15006546
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups.
    Brabec V; Neplechova K; Kasparkova J; Farrell N
    J Biol Inorg Chem; 2000 Jun; 5(3):364-8. PubMed ID: 10907747
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA adducts of antitumor trans-[PtCl2 (E-imino ether)2].
    Brabec V; Vrána O; Nováková O; Kleinwächter V; Intini FP; Coluccia M; Natile G
    Nucleic Acids Res; 1996 Jan; 24(2):336-41. PubMed ID: 8628659
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Replacement of an NH(3) by an iminoether in transplatin makes an antitumor drug from an inactive compound.
    Leng M; Locker D; Giraud-Panis MJ; Schwartz A; Intini FP; Natile G; Pisano C; Boccarelli A; Giordano D; Coluccia M
    Mol Pharmacol; 2000 Dec; 58(6):1525-35. PubMed ID: 11093793
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.