These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 16210249)

  • 1. A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function.
    Rottmann S; Wang Y; Nasoff M; Deveraux QL; Quon KC
    Proc Natl Acad Sci U S A; 2005 Oct; 102(42):15195-200. PubMed ID: 16210249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M; Orian A; Jin J; Grim JE; Harper JW; Eisenman RN; Clurman BE
    Proc Natl Acad Sci U S A; 2004 Jun; 101(24):9085-90. PubMed ID: 15150404
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K; Hiramatsu Y; Uchida C; Isobe T; Hattori T; Oda T; Shibata K; Nakamura S; Kikuchi A; Kitagawa M
    Oncogene; 2009 Jun; 28(25):2393-405. PubMed ID: 19421138
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
    Wei W; Jin J; Schlisio S; Harper JW; Kaelin WG
    Cancer Cell; 2005 Jul; 8(1):25-33. PubMed ID: 16023596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K; Douglas L; Delaney A; Houghton JA
    Clin Cancer Res; 2004 Oct; 10(19):6650-60. PubMed ID: 15475455
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis.
    Huang HL; Weng HY; Wang LQ; Yu CH; Huang QJ; Zhao PP; Wen JZ; Zhou H; Qu LH
    Mol Cancer Ther; 2012 May; 11(5):1155-65. PubMed ID: 22389469
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549.
    Chen XM; Bai Y; Zhong YJ; Xie XL; Long HW; Yang YY; Wu SG; Jia Q; Wang XH
    PLoS One; 2013; 8(11):e79201. PubMed ID: 24265759
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myc tagging along the TRAIL to death receptor 5.
    Sheikh MS
    Cell Cycle; 2004 Jul; 3(7):920-2. PubMed ID: 15254425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
    Zhao D; Zheng HQ; Zhou Z; Chen C
    Cancer Res; 2010 Jun; 70(11):4728-38. PubMed ID: 20484041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.
    Wang S; El-Deiry WS
    Proc Natl Acad Sci U S A; 2003 Dec; 100(25):15095-100. PubMed ID: 14645705
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glycogen synthase kinase-3beta suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer.
    Liao X; Zhang L; Thrasher JB; Du J; Li B
    Mol Cancer Ther; 2003 Nov; 2(11):1215-22. PubMed ID: 14617795
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
    Ganten TM; Haas TL; Sykora J; Stahl H; Sprick MR; Fas SC; Krueger A; Weigand MA; Grosse-Wilde A; Stremmel W; Krammer PH; Walczak H
    Cell Death Differ; 2004 Jul; 11 Suppl 1():S86-96. PubMed ID: 15105837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.
    Kim YS; Schwabe RF; Qian T; Lemasters JJ; Brenner DA
    Hepatology; 2002 Dec; 36(6):1498-508. PubMed ID: 12447876
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H; Shaik S; Onoyama I; Gao D; Tseng A; Maser RS; Zhai B; Wan L; Gutierrez A; Lau AW; Xiao Y; Christie AL; Aster J; Settleman J; Gygi SP; Kung AL; Look T; Nakayama KI; DePinho RA; Wei W
    Nature; 2011 Mar; 471(7336):104-9. PubMed ID: 21368833
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.
    Ricci MS; Jin Z; Dews M; Yu D; Thomas-Tikhonenko A; Dicker DT; El-Deiry WS
    Mol Cell Biol; 2004 Oct; 24(19):8541-55. PubMed ID: 15367674
    [TBL] [Abstract][Full Text] [Related]  

  • 16. E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
    Lochab S; Pal P; Kapoor I; Kanaujiya JK; Sanyal S; Behre G; Trivedi AK
    Biochim Biophys Acta; 2013 Dec; 1833(12):2639-2652. PubMed ID: 23820376
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
    Xiao D; Yue M; Su H; Ren P; Jiang J; Li F; Hu Y; Du H; Liu H; Qing G
    Mol Cell; 2016 Nov; 64(3):493-506. PubMed ID: 27773673
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
    Yada M; Hatakeyama S; Kamura T; Nishiyama M; Tsunematsu R; Imaki H; Ishida N; Okumura F; Nakayama K; Nakayama KI
    EMBO J; 2004 May; 23(10):2116-25. PubMed ID: 15103331
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells.
    Chen XM; Xie XB; Zhao Q; Wang F; Bai Y; Yin JQ; Jiang H; Xie XL; Jia Q; Huang G
    Mol Med Rep; 2015 Jan; 11(1):105-12. PubMed ID: 25333250
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.