BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 16210316)

  • 1. Activation of the Src family kinase Hck without SH3-linker release.
    Lerner EC; Trible RP; Schiavone AP; Hochrein JM; Engen JR; Smithgall TE
    J Biol Chem; 2005 Dec; 280(49):40832-7. PubMed ID: 16210316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant activation mechanism.
    Alvarado JJ; Betts L; Moroco JA; Smithgall TE; Yeh JI
    J Biol Chem; 2010 Nov; 285(46):35455-61. PubMed ID: 20810664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
    Alvarado JJ; Tarafdar S; Yeh JI; Smithgall TE
    J Biol Chem; 2014 Oct; 289(41):28539-53. PubMed ID: 25122770
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo.
    Lerner EC; Smithgall TE
    Nat Struct Biol; 2002 May; 9(5):365-9. PubMed ID: 11976726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in Rat-2 fibroblasts.
    Briggs SD; Smithgall TE
    J Biol Chem; 1999 Sep; 274(37):26579-83. PubMed ID: 10473622
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of the SH3-SH2 domain linker sequence on the structure of Hck kinase.
    Meiselbach H; Sticht H
    J Mol Model; 2011 Aug; 17(8):1927-34. PubMed ID: 21110053
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.
    Schreiner SJ; Schiavone AP; Smithgall TE
    J Biol Chem; 2002 Nov; 277(47):45680-7. PubMed ID: 12244095
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.
    Briggs SD; Lerner EC; Smithgall TE
    Biochemistry; 2000 Jan; 39(3):489-95. PubMed ID: 10642173
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
    Moarefi I; LaFevre-Bernt M; Sicheri F; Huse M; Lee CH; Kuriyan J; Miller WT
    Nature; 1997 Feb; 385(6617):650-3. PubMed ID: 9024665
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions.
    Williams JC; Weijland A; Gonfloni S; Thompson A; Courtneidge SA; Superti-Furga G; Wierenga RK
    J Mol Biol; 1997 Dec; 274(5):757-75. PubMed ID: 9405157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polyomavirus middle-T antigen associates with the kinase domain of Src-related tyrosine kinases.
    Dunant NM; Senften M; Ballmer-Hofer K
    J Virol; 1996 Mar; 70(3):1323-30. PubMed ID: 8627648
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction.
    Trible RP; Emert-Sedlak L; Smithgall TE
    J Biol Chem; 2006 Sep; 281(37):27029-38. PubMed ID: 16849330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue.
    LaFevre-Bernt M; Sicheri F; Pico A; Porter M; Kuriyan J; Miller WT
    J Biol Chem; 1998 Nov; 273(48):32129-34. PubMed ID: 9822689
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.
    Briggs SD; Sharkey M; Stevenson M; Smithgall TE
    J Biol Chem; 1997 Jul; 272(29):17899-902. PubMed ID: 9218412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
    Dutartre H; Harris M; Olive D; Collette Y
    Virology; 1998 Aug; 247(2):200-11. PubMed ID: 9705913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand.
    Porter M; Schindler T; Kuriyan J; Miller WT
    J Biol Chem; 2000 Jan; 275(4):2721-6. PubMed ID: 10644735
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
    Arold S; O'Brien R; Franken P; Strub MP; Hoh F; Dumas C; Ladbury JE
    Biochemistry; 1998 Oct; 37(42):14683-91. PubMed ID: 9778343
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.
    Gonfloni S; Williams JC; Hattula K; Weijland A; Wierenga RK; Superti-Furga G
    EMBO J; 1997 Dec; 16(24):7261-71. PubMed ID: 9405355
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Non-peptide Small Molecule Allosteric Modulators of the Src-family Kinase, Hck.
    Dorman HR; Close D; Wingert BM; Camacho CJ; Johnston PA; Smithgall TE
    Front Chem; 2019; 7():822. PubMed ID: 31850311
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X.
    Shi X; Opi S; Lugari A; Restouin A; Coursindel T; Parrot I; Perez J; Madore E; Zimmermann P; Corbeil J; Huang M; Arold ST; Collette Y; Morelli X
    Biochem J; 2010 Oct; 431(1):93-102. PubMed ID: 20670214
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.