201 related articles for article (PubMed ID: 16212960)
1. Identification of plasma membrane associated mature beta-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts.
Mencarelli S; Cavalieri C; Magini A; Tancini B; Basso L; Lemansky P; Hasilik A; Li YT; Chigorno V; Orlacchio A; Emiliani C; Sonnino S
FEBS Lett; 2005 Oct; 579(25):5501-6. PubMed ID: 16212960
[TBL] [Abstract][Full Text] [Related]
2. Identification and characterization of mature beta-hexosaminidases associated with human placenta lysosomal membrane.
Magini A; Mencarelli S; Tancini B; Ciccarone V; Urbanelli L; Hasilik A; Emiliani C
Biosci Rep; 2008 Aug; 28(4):229-37. PubMed ID: 18588514
[TBL] [Abstract][Full Text] [Related]
3. A selective inhibitor Gal-PUGNAc of human lysosomal beta-hexosaminidases modulates levels of the ganglioside GM2 in neuroblastoma cells.
Stubbs KA; Macauley MS; Vocadlo DJ
Angew Chem Int Ed Engl; 2009; 48(7):1300-3. PubMed ID: 19130519
[TBL] [Abstract][Full Text] [Related]
4. Restoration of hexosaminidase A activity in human Tay-Sachs fibroblasts via adenoviral vector-mediated gene transfer.
Akli S; Guidotti JE; Vigne E; Perricaudet M; Sandhoff K; Kahn A; Poenaru L
Gene Ther; 1996 Sep; 3(9):769-74. PubMed ID: 8875224
[TBL] [Abstract][Full Text] [Related]
5. Ganglioside GM2 levels in human melanoma cells: inverse correlation with lysosomal beta-hexosaminidase A activity.
Hoon DS; Kaback MM; Lim-Steele J; Tsuchida T; Morton DL; Irie RF
Biochem Int; 1992 Jul; 27(2):343-52. PubMed ID: 1386984
[TBL] [Abstract][Full Text] [Related]
6. Direct determination of the substrate specificity of the alpha-active site in heterodimeric beta-hexosaminidase A.
Hou Y; Tse R; Mahuran DJ
Biochemistry; 1996 Apr; 35(13):3963-9. PubMed ID: 8672428
[TBL] [Abstract][Full Text] [Related]
7. Lysosomal enzyme precursors in human fibroblasts. Activation of cathepsin D precursor in vitro and activity of beta-hexosaminidase A precursor towards ganglioside GM2.
Hasilik A; von Figura K; Conzelmann E; Nehrkorn H; Sandhoff K
Eur J Biochem; 1982 Jul; 125(2):317-21. PubMed ID: 6214395
[TBL] [Abstract][Full Text] [Related]
8. Identification of functional domains within the alpha and beta subunits of beta-hexosaminidase A through the expression of alpha-beta fusion proteins.
Tse R; Wu YJ; Vavougios G; Hou Y; Hinek A; Mahuran DJ
Biochemistry; 1996 Aug; 35(33):10894-903. PubMed ID: 8718882
[TBL] [Abstract][Full Text] [Related]
9. Retrovirus-mediated transfer and expression of beta-hexosaminidase alpha-chain cDNA in human fibroblasts from G(M2)-gangliosidosis B1 variant.
Teixeira CA; Sena-Esteves M; Lopes L; Sá Miranda MC; Ribeiro MG
Hum Gene Ther; 2001 Sep; 12(14):1771-83. PubMed ID: 11560770
[TBL] [Abstract][Full Text] [Related]
10. Degradation of membrane-bound ganglioside GM2 by beta -hexosaminidase A. Stimulation by GM2 activator protein and lysosomal lipids.
Werth N; Schuette CG; Wilkening G; Lemm T; Sandhoff K
J Biol Chem; 2001 Apr; 276(16):12685-90. PubMed ID: 11278374
[TBL] [Abstract][Full Text] [Related]
11. Therapeutic evaluation of GM2 gangliosidoses by ELISA using anti-GM2 ganglioside antibodies.
Tsuji D; Higashine Y; Matsuoka K; Sakuraba H; Itoh K
Clin Chim Acta; 2007 Mar; 378(1-2):38-41. PubMed ID: 17196574
[TBL] [Abstract][Full Text] [Related]
12. Formation of a ternary complex between GM2 activator protein, GM2 ganglioside and hexosaminidase A.
Yadao F; Hechtman P; Kaplan F
Biochim Biophys Acta; 1997 Jun; 1340(1):45-52. PubMed ID: 9217013
[TBL] [Abstract][Full Text] [Related]
13. Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts.
Arfi A; Bourgoin C; Basso L; Emiliani C; Tancini B; Chigorno V; Li YT; Orlacchio A; Poenaru L; Sonnino S; Caillaud C
Neurobiol Dis; 2005 Nov; 20(2):583-93. PubMed ID: 15953731
[TBL] [Abstract][Full Text] [Related]
14. Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes.
Magini A; Polchi A; Tancini B; Urbanelli L; Hasilik A; Emiliani C
Biochimie; 2012 Mar; 94(3):684-94. PubMed ID: 21978926
[TBL] [Abstract][Full Text] [Related]
15. Hexosaminidase A activity in skin fibroblasts from various types of GM2 gangliosidosis using a fluorogenic sulphated substrate.
Inui K; Yutaka T; Okada S; Yabuuchi H; Wenger DA; Desnick RJ
J Inherit Metab Dis; 1985; 8(3):149-50. PubMed ID: 2949109
[No Abstract] [Full Text] [Related]
16. The enzyme-binding region of human GM2-activator protein.
Wendeler M; Werth N; Maier T; Schwarzmann G; Kolter T; Schoeniger M; Hoffmann D; Lemm T; Saenger W; Sandhoff K
FEBS J; 2006 Mar; 273(5):982-91. PubMed ID: 16478472
[TBL] [Abstract][Full Text] [Related]
17. Induced secretion of beta-hexosaminidase by human brain endothelial cells: a novel approach in Sandhoff disease?
Batista L; Miller F; Clave C; Arfi A; Douillard-Guilloux G; Couraud PO; Caillaud C
Neurobiol Dis; 2010 Mar; 37(3):656-60. PubMed ID: 20005954
[TBL] [Abstract][Full Text] [Related]
18. Identification of domains in human beta-hexosaminidase that determine substrate specificity.
Pennybacker M; Liessem B; Moczall H; Tifft CJ; Sandhoff K; Proia RL
J Biol Chem; 1996 Jul; 271(29):17377-82. PubMed ID: 8663217
[TBL] [Abstract][Full Text] [Related]
19. A novel missense mutation (C522Y) is present in the beta-hexosaminidase beta-subunit gene of a Japanese patient with infantile Sandhoff disease.
Kuroki Y; Itoh K; Nadaoka Y; Tanaka T; Sakuraba H
Biochem Biophys Res Commun; 1995 Jul; 212(2):564-71. PubMed ID: 7626071
[TBL] [Abstract][Full Text] [Related]
20. A single site in human beta-hexosaminidase A binds both 6-sulfate-groups on hexosamines and the sialic acid moiety of GM2 ganglioside.
Sharma R; Bukovac S; Callahan J; Mahuran D
Biochim Biophys Acta; 2003 Jan; 1637(1):113-8. PubMed ID: 12527415
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
