BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 16214430)

  • 1. Dynamics of signaling by PKA.
    Taylor SS; Kim C; Vigil D; Haste NM; Yang J; Wu J; Anand GS
    Biochim Biophys Acta; 2005 Dec; 1754(1-2):25-37. PubMed ID: 16214430
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA.
    Kim C; Xuong NH; Taylor SS
    Science; 2005 Feb; 307(5710):690-6. PubMed ID: 15692043
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Probing cAMP-dependent protein kinase holoenzyme complexes I alpha and II beta by FT-IR and chemical protein footprinting.
    Yu S; Mei FC; Lee JC; Cheng X
    Biochemistry; 2004 Feb; 43(7):1908-20. PubMed ID: 14967031
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mapping intersubunit interactions of the regulatory subunit (RIalpha) in the type I holoenzyme of protein kinase A by amide hydrogen/deuterium exchange mass spectrometry (DXMS).
    Hamuro Y; Anand GS; Kim JS; Juliano C; Stranz DD; Taylor SS; Woods VL
    J Mol Biol; 2004 Jul; 340(5):1185-96. PubMed ID: 15236976
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
    Kim C; Cheng CY; Saldanha SA; Taylor SS
    Cell; 2007 Sep; 130(6):1032-43. PubMed ID: 17889648
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions.
    Vigil D; Blumenthal DK; Heller WT; Brown S; Canaves JM; Taylor SS; Trewhella J
    J Mol Biol; 2004 Apr; 337(5):1183-94. PubMed ID: 15046986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamic binding of PKA regulatory subunit RI alpha.
    Gullingsrud J; Kim C; Taylor SS; McCammon JA
    Structure; 2006 Jan; 14(1):141-9. PubMed ID: 16407073
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The conformationally dynamic C helix of the RIalpha subunit of protein kinase A mediates isoform-specific domain reorganization upon C subunit binding.
    Vigil D; Blumenthal DK; Taylor SS; Trewhella J
    J Biol Chem; 2005 Oct; 280(42):35521-7. PubMed ID: 16109722
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Isoform specific differences in binding of a dual-specificity A-kinase anchoring protein to type I and type II regulatory subunits of PKA.
    Burns LL; Canaves JM; Pennypacker JK; Blumenthal DK; Taylor SS
    Biochemistry; 2003 May; 42(19):5754-63. PubMed ID: 12741833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP.
    Wu J; Jones JM; Nguyen-Huu X; Ten Eyck LF; Taylor SS
    Biochemistry; 2004 Jun; 43(21):6620-9. PubMed ID: 15157095
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP.
    Lu TW; Wu J; Aoto PC; Weng JH; Ahuja LG; Sun N; Cheng CY; Zhang P; Taylor SS
    Proc Natl Acad Sci U S A; 2019 Aug; 116(33):16347-16356. PubMed ID: 31363049
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclic-AMP and pseudosubstrate effects on type-I A-kinase regulatory and catalytic subunit binding kinetics.
    Anand G; Taylor SS; Johnson DA
    Biochemistry; 2007 Aug; 46(32):9283-91. PubMed ID: 17658893
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change.
    Heller WT; Vigil D; Brown S; Blumenthal DK; Taylor SS; Trewhella J
    J Biol Chem; 2004 Apr; 279(18):19084-90. PubMed ID: 14985329
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα.
    Akimoto M; McNicholl ET; Ramkissoon A; Moleschi K; Taylor SS; Melacini G
    PLoS Biol; 2015; 13(11):e1002305. PubMed ID: 26618408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential effects of substrate on type I and type II PKA holoenzyme dissociation.
    Vigil D; Blumenthal DK; Brown S; Taylor SS; Trewhella J
    Biochemistry; 2004 May; 43(19):5629-36. PubMed ID: 15134437
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme.
    Boettcher AJ; Wu J; Kim C; Yang J; Bruystens J; Cheung N; Pennypacker JK; Blumenthal DA; Kornev AP; Taylor SS
    Structure; 2011 Feb; 19(2):265-76. PubMed ID: 21300294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity.
    Wu J; Brown SH; von Daake S; Taylor SS
    Science; 2007 Oct; 318(5848):274-9. PubMed ID: 17932298
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.
    Taylor SS; Kim C; Cheng CY; Brown SH; Wu J; Kannan N
    Biochim Biophys Acta; 2008 Jan; 1784(1):16-26. PubMed ID: 17996741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system.
    Carlson CR; Ruppelt A; Taskén K
    J Mol Biol; 2003 Mar; 327(3):609-18. PubMed ID: 12634056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein docking.
    Anand GS; Law D; Mandell JG; Snead AN; Tsigelny I; Taylor SS; Ten Eyck LF; Komives EA
    Proc Natl Acad Sci U S A; 2003 Nov; 100(23):13264-9. PubMed ID: 14583592
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.