These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

382 related articles for article (PubMed ID: 16215987)

  • 1. Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex.
    Jao DL; Chen KY
    J Cell Biochem; 2006 Feb; 97(3):583-98. PubMed ID: 16215987
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The deoxyhypusine synthase mutant dys1-1 reveals the association of eIF5A and Asc1 with cell wall integrity.
    Galvão FC; Rossi D; Silveira Wda S; Valentini SR; Zanelli CF
    PLoS One; 2013; 8(4):e60140. PubMed ID: 23573236
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
    Park MH
    J Biochem; 2006 Feb; 139(2):161-9. PubMed ID: 16452303
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor.
    Lee YB; Joe YA; Wolff EC; Dimitriadis EK; Park MH
    Biochem J; 1999 May; 340 ( Pt 1)(Pt 1):273-81. PubMed ID: 10229683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
    Park JH; Dias CA; Lee SB; Valentini SR; Sokabe M; Fraser CS; Park MH
    Protein Eng Des Sel; 2011 Mar; 24(3):301-9. PubMed ID: 21131325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Higher activity of recombinant bovine deoxyhypusine synthase vs. human deoxyhypusine synthase.
    Huang JK; Tsai S; Huang GH; Gowda PG; Walzer AM; Wen L
    Protein Expr Purif; 2004 May; 35(1):32-8. PubMed ID: 15039063
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Post-translational formation of hypusine in eIF5A: implications in human neurodevelopment.
    Park MH; Kar RK; Banka S; Ziegler A; Chung WK
    Amino Acids; 2022 Apr; 54(4):485-499. PubMed ID: 34273022
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the Ribosome.
    Rossi D; Barbosa NM; Galvão FC; Boldrin PE; Hershey JW; Zanelli CF; Fraser CS; Valentini SR
    PLoS One; 2016; 11(4):e0154205. PubMed ID: 27115996
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
    Wolff EC; Kang KR; Kim YS; Park MH
    Amino Acids; 2007 Aug; 33(2):341-50. PubMed ID: 17476569
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder.
    Ganapathi M; Padgett LR; Yamada K; Devinsky O; Willaert R; Person R; Au PB; Tagoe J; McDonald M; Karlowicz D; Wolf B; Lee J; Shen Y; Okur V; Deng L; LeDuc CA; Wang J; Hanner A; Mirmira RG; Park MH; Mastracci TL; Chung WK
    Am J Hum Genet; 2019 Feb; 104(2):287-298. PubMed ID: 30661771
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.
    Nishimura K; Lee SB; Park JH; Park MH
    Amino Acids; 2012 Feb; 42(2-3):703-10. PubMed ID: 21850436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
    Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mapping surface residues of eIF5A that are important for binding to the ribosome using alanine scanning mutagenesis.
    Barbosa NM; Boldrin PE; Rossi D; Yamamoto PA; Watanabe TF; Serrão VH; Hershey JW; Fraser CS; Valentini SR; Zanelli CF
    Amino Acids; 2016 Oct; 48(10):2363-74. PubMed ID: 27388480
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.
    Kar RK; Hanner AS; Starost MF; Springer D; Mastracci TL; Mirmira RG; Park MH
    J Biol Chem; 2021 Nov; 297(5):101333. PubMed ID: 34688659
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
    Melnikov S; Mailliot J; Shin BS; Rigger L; Yusupova G; Micura R; Dever TE; Yusupov M
    J Mol Biol; 2016 Sep; 428(18):3570-3576. PubMed ID: 27196944
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational analyses of human eIF5A-1--identification of amino acid residues critical for eIF5A activity and hypusine modification.
    Cano VS; Jeon GA; Johansson HE; Henderson CA; Park JH; Valentini SR; Hershey JW; Park MH
    FEBS J; 2008 Jan; 275(1):44-58. PubMed ID: 18067580
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Many Faces of Hypusinated eIF5A: Cell Context-Specific Effects of the Hypusine Circuit and Implications for Human Health.
    Nakanishi S; Cleveland JL
    Int J Mol Sci; 2024 Jul; 25(15):. PubMed ID: 39125743
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional significance of eIF5A and its hypusine modification in eukaryotes.
    Park MH; Nishimura K; Zanelli CF; Valentini SR
    Amino Acids; 2010 Feb; 38(2):491-500. PubMed ID: 19997760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis.
    Lee Y; Kim HK; Park HE; Park MH; Joe YA
    Mol Cell Biochem; 2002 Aug; 237(1-2):69-76. PubMed ID: 12236588
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular cloning of bovine eIF5A and deoxyhypusine synthase cDNA.
    Huang JK; Tsai S; Huang GH; Sershon VC; Alley AM; Wen L
    DNA Seq; 2004 Feb; 15(1):26-32. PubMed ID: 15354351
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.