BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 16219495)

  • 1. Kinetic characterization of Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomerase mutants.
    Fernandes RP; Proteau PJ
    Biochim Biophys Acta; 2006 Feb; 1764(2):223-9. PubMed ID: 16219495
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutation in the flexible loop of 1-deoxy-D-xylulose 5-phosphate reductoisomerase broadens substrate utilization.
    Fernandes RP; Phaosiri C; Proteau PJ
    Arch Biochem Biophys; 2005 Dec; 444(2):159-64. PubMed ID: 16289362
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target.
    Henriksson LM; Björkelid C; Mowbray SL; Unge T
    Acta Crystallogr D Biol Crystallogr; 2006 Jul; 62(Pt 7):807-13. PubMed ID: 16790937
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.
    Proteau PJ
    Bioorg Chem; 2004 Dec; 32(6):483-93. PubMed ID: 15530989
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
    Woo YH; Fernandes RP; Proteau PJ
    Bioorg Med Chem; 2006 Apr; 14(7):2375-85. PubMed ID: 16310360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
    Mac Sweeney A; Lange R; Fernandes RP; Schulz H; Dale GE; Douangamath A; Proteau PJ; Oefner C
    J Mol Biol; 2005 Jan; 345(1):115-27. PubMed ID: 15567415
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from the hyperthermophile Thermotoga maritima for insights into the coordination of conformational changes and an inhibitor binding.
    Takenoya M; Ohtaki A; Noguchi K; Endo K; Sasaki Y; Ohsawa K; Yajima S; Yohda M
    J Struct Biol; 2010 Jun; 170(3):532-9. PubMed ID: 20353826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis.
    Henriksson LM; Unge T; Carlsson J; Aqvist J; Mowbray SL; Jones TA
    J Biol Chem; 2007 Jul; 282(27):19905-16. PubMed ID: 17491006
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystallization and preliminary X-ray crystallographic study of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Plasmodium falciparum.
    Umeda T; Tanaka N; Kusakabe Y; Nakanishi M; Kitade Y; Nakamura KT
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2010 Mar; 66(Pt 3):330-2. PubMed ID: 20208174
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.
    Singh VK; Ghosh I
    FEBS Lett; 2013 Sep; 587(17):2806-17. PubMed ID: 23816706
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution.
    Ricagno S; Grolle S; Bringer-Meyer S; Sahm H; Lindqvist Y; Schneider G
    Biochim Biophys Acta; 2004 Apr; 1698(1):37-44. PubMed ID: 15063313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
    Grolle S; Bringer-Meyer S; Sahm H
    FEMS Microbiol Lett; 2000 Oct; 191(1):131-7. PubMed ID: 11004410
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Computational analysis of the evolution of 1-deoxy-D-xylulose-5-phosphate Reductoisomerase, an important enzyme in plant terpene biosynthesis.
    Fung PK; Krushkal J; Weathers PJ
    Chem Biodivers; 2010 May; 7(5):1098-110. PubMed ID: 20491066
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues.
    Kuzuyama T; Takahashi S; Takagi M; Seto H
    J Biol Chem; 2000 Jun; 275(26):19928-32. PubMed ID: 10787409
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of native and histidine-tagged deoxyxylulose 5-phosphate reductoisomerase from the cyanobacterium Synechocystis sp. PCC6803.
    Yin X; Proteau PJ
    Biochim Biophys Acta; 2003 Nov; 1652(1):75-81. PubMed ID: 14580998
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation.
    Phaosiri C; Proteau PJ
    Bioorg Med Chem Lett; 2004 Nov; 14(21):5309-12. PubMed ID: 15454217
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway.
    Carretero-Paulet L; Ahumada I; Cunillera N; Rodríguez-Concepción M; Ferrer A; Boronat A; Campos N
    Plant Physiol; 2002 Aug; 129(4):1581-91. PubMed ID: 12177470
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cloning and heterologous expression of a cDNA encoding 1-deoxy-D-xylulose-5-phosphate reductoisomerase of Arabidopsis thaliana.
    Schwender J; Müller C; Zeidler J; Lichtenthaler HK
    FEBS Lett; 1999 Jul; 455(1-2):140-4. PubMed ID: 10428488
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin.
    Yajima S; Hara K; Iino D; Sasaki Y; Kuzuyama T; Ohsawa K; Seto H
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2007 Jun; 63(Pt 6):466-70. PubMed ID: 17554164
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis.
    Takahashi S; Kuzuyama T; Watanabe H; Seto H
    Proc Natl Acad Sci U S A; 1998 Aug; 95(17):9879-84. PubMed ID: 9707569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.