BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1877 related articles for article (PubMed ID: 16219905)

  • 1. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S; Ichikawa H; Takada Y; Sandur SK; Shishodia S; Aggarwal BB
    Mol Pharmacol; 2006 Jan; 69(1):195-206. PubMed ID: 16219905
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
    Takada Y; Ichikawa H; Pataer A; Swisher S; Aggarwal BB
    Oncogene; 2007 Feb; 26(8):1201-12. PubMed ID: 16924232
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression.
    Shishodia S; Aggarwal BB
    Oncogene; 2006 Mar; 25(10):1463-73. PubMed ID: 16331273
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
    Takada Y; Murakami A; Aggarwal BB
    Oncogene; 2005 Oct; 24(46):6957-69. PubMed ID: 16007145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.
    Tse AK; Wan CK; Shen XL; Yang M; Fong WF
    Biochem Pharmacol; 2005 Nov; 70(10):1443-57. PubMed ID: 16181613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
    Pandey MK; Sung B; Kunnumakkara AB; Sethi G; Chaturvedi MM; Aggarwal BB
    Cancer Res; 2008 Jul; 68(13):5370-9. PubMed ID: 18593939
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis.
    Shakibaei M; John T; Schulze-Tanzil G; Lehmann I; Mobasheri A
    Biochem Pharmacol; 2007 May; 73(9):1434-45. PubMed ID: 17291458
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.
    Tse AK; Wan CK; Zhu GY; Shen XL; Cheung HY; Yang M; Fong WF
    Mol Immunol; 2007 Apr; 44(10):2647-58. PubMed ID: 17240450
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation.
    Sethi G; Ahn KS; Sung B; Kunnumakkara AB; Chaturvedi MM; Aggarwal BB
    Biochem Pharmacol; 2008 Dec; 76(11):1404-16. PubMed ID: 18606397
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation.
    Takada Y; Bhardwaj A; Potdar P; Aggarwal BB
    Oncogene; 2004 Dec; 23(57):9247-58. PubMed ID: 15489888
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.
    Aggarwal BB; Shishodia S; Takada Y; Banerjee S; Newman RA; Bueso-Ramos CE; Price JE
    Clin Cancer Res; 2005 Oct; 11(20):7490-8. PubMed ID: 16243823
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor kappaB activation.
    Ozaki I; Zhang H; Mizuta T; Ide Y; Eguchi Y; Yasutake T; Sakamaki T; Pestell RG; Yamamoto K
    Clin Cancer Res; 2007 Apr; 13(7):2236-45. PubMed ID: 17404108
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products.
    Kunnumakkara AB; Diagaradjane P; Guha S; Deorukhkar A; Shentu S; Aggarwal BB; Krishnan S
    Clin Cancer Res; 2008 Apr; 14(7):2128-36. PubMed ID: 18381954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.
    Jackson-Bernitsas DG; Ichikawa H; Takada Y; Myers JN; Lin XL; Darnay BG; Chaturvedi MM; Aggarwal BB
    Oncogene; 2007 Mar; 26(10):1385-97. PubMed ID: 16953224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated kinase, and nuclear factor-kappaB/Rel signaling pathways.
    Kang JS; Yoon YD; Han MH; Han SB; Lee K; Lee KH; Park SK; Kim HM
    Mol Pharmacol; 2006 Mar; 69(3):941-9. PubMed ID: 16354764
    [TBL] [Abstract][Full Text] [Related]  

  • 16. cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt.
    Hwang DM; Kundu JK; Shin JW; Lee JC; Lee HJ; Surh YJ
    Carcinogenesis; 2007 Feb; 28(2):363-71. PubMed ID: 16950795
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera.
    Lee JH; Jung HS; Giang PM; Jin X; Lee S; Son PT; Lee D; Hong YS; Lee K; Lee JJ
    J Pharmacol Exp Ther; 2006 Jan; 316(1):271-8. PubMed ID: 16183703
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
    Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B; Pandey MK; Aggarwal BB
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases.
    Ahn KS; Gong X; Sethi G; Chaturvedi MM; Jaiswal AK; Aggarwal BB
    Cancer Res; 2007 Oct; 67(20):10004-11. PubMed ID: 17942934
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 94.