BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 16220973)

  • 1. G-protein-coupled receptor affinity prediction based on the use of a profiling dataset: QSAR design, synthesis, and experimental validation.
    Rolland C; Gozalbes R; Nicolaï E; Paugam MF; Coussy L; Barbosa F; Horvath D; Revah F
    J Med Chem; 2005 Oct; 48(21):6563-74. PubMed ID: 16220973
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug design strategies for targeting G-protein-coupled receptors.
    Klabunde T; Hessler G
    Chembiochem; 2002 Oct; 3(10):928-44. PubMed ID: 12362358
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PREDICT modeling and in-silico screening for G-protein coupled receptors.
    Shacham S; Marantz Y; Bar-Haim S; Kalid O; Warshaviak D; Avisar N; Inbal B; Heifetz A; Fichman M; Topf M; Naor Z; Noiman S; Becker OM
    Proteins; 2004 Oct; 57(1):51-86. PubMed ID: 15326594
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Virtual screen for ligands of orphan G protein-coupled receptors.
    Bock JR; Gough DA
    J Chem Inf Model; 2005; 45(5):1402-14. PubMed ID: 16180917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combinatorial QSAR modeling of specificity and subtype selectivity of ligands binding to serotonin receptors 5HT1E and 5HT1F.
    Wang XS; Tang H; Golbraikh A; Tropsha A
    J Chem Inf Model; 2008 May; 48(5):997-1013. PubMed ID: 18470978
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols.
    Evers A; Hessler G; Matter H; Klabunde T
    J Med Chem; 2005 Aug; 48(17):5448-65. PubMed ID: 16107144
    [TBL] [Abstract][Full Text] [Related]  

  • 7. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
    Heilker R; Wolff M; Tautermann CS; Bieler M
    Drug Discov Today; 2009 Mar; 14(5-6):231-40. PubMed ID: 19121411
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The 7 TM G-protein-coupled receptor target family.
    Jacoby E; Bouhelal R; Gerspacher M; Seuwen K
    ChemMedChem; 2006 Aug; 1(8):761-82. PubMed ID: 16902930
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A screening library for peptide activated G-protein coupled receptors. 1. The test set.
    Lavrador K; Murphy B; Saunders J; Struthers S; Wang X; Williams J
    J Med Chem; 2004 Dec; 47(27):6864-74. PubMed ID: 15615535
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development and validation of a novel protein-ligand fingerprint to mine chemogenomic space: application to G protein-coupled receptors and their ligands.
    Weill N; Rognan D
    J Chem Inf Model; 2009 Apr; 49(4):1049-62. PubMed ID: 19301874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
    Bhattacharya S; Hall SE; Vaidehi N
    J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Finding ligands for G protein-coupled receptors based on the protein-compound affinity matrix.
    Fukunishi Y; Kubota S; Nakamura H
    J Mol Graph Model; 2007 Jan; 25(5):633-43. PubMed ID: 16777448
    [TBL] [Abstract][Full Text] [Related]  

  • 13. QSAR study of selective ligands for the thyroid hormone receptor beta.
    Liu H; Gramatica P
    Bioorg Med Chem; 2007 Aug; 15(15):5251-61. PubMed ID: 17524652
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel ligands for the chemokine receptor-3 (CCR3): a receptor-modeling study based on 5D-QSAR.
    Vedani A; Dobler M; Dollinger H; Hasselbach KM; Birke F; Lill MA
    J Med Chem; 2005 Mar; 48(5):1515-27. PubMed ID: 15743194
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design of a gene family screening library targeting G-protein coupled receptors.
    Lamb ML; Bradley EK; Beaton G; Bondy SS; Castellino AJ; Gibbons PA; Suto MJ; Grootenhuis PD
    J Mol Graph Model; 2004 Sep; 23(1):15-21. PubMed ID: 15331050
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rough set-based proteochemometrics modeling of G-protein-coupled receptor-ligand interactions.
    Strömbergsson H; Prusis P; Midelfart H; Lapinsh M; Wikberg JE; Komorowski J
    Proteins; 2006 Apr; 63(1):24-34. PubMed ID: 16435365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Homology model-based virtual screening for GPCR ligands using docking and target-biased scoring.
    Radestock S; Weil T; Renner S
    J Chem Inf Model; 2008 May; 48(5):1104-17. PubMed ID: 18442221
    [TBL] [Abstract][Full Text] [Related]  

  • 18. From astemizole to a novel hit series of small-molecule somatostatin 5 receptor antagonists via GPCR affinity profiling.
    Guba W; Green LG; Martin RE; Roche O; Kratochwil N; Mauser H; Bissantz C; Christ A; Stahl M
    J Med Chem; 2007 Dec; 50(25):6295-8. PubMed ID: 18020391
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relaxin-3, INSL5, and their receptors.
    Liu C; Lovenberg TW
    Results Probl Cell Differ; 2008; 46():213-37. PubMed ID: 18236022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Orthosteric/allosteric bitopic ligands: going hybrid at GPCRs.
    Valant C; Sexton PM; Christopoulos A
    Mol Interv; 2009 Jun; 9(3):125-35. PubMed ID: 19592673
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.