BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

764 related articles for article (PubMed ID: 16227609)

  • 1. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
    Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
    Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3.
    LeBron C; Chen L; Gilkes DM; Chen J
    EMBO J; 2006 Mar; 25(6):1196-206. PubMed ID: 16511560
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance.
    Kulikov R; Boehme KA; Blattner C
    Mol Cell Biol; 2005 Aug; 25(16):7170-80. PubMed ID: 16055726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of p53-MDMX interaction by casein kinase 1 alpha.
    Chen L; Li C; Pan Y; Chen J
    Mol Cell Biol; 2005 Aug; 25(15):6509-20. PubMed ID: 16024788
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
    Ghosh M; Huang K; Berberich SJ
    Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
    Okamoto K; Taya Y; Nakagama H
    FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts.
    Gentiletti F; Mancini F; D'Angelo M; Sacchi A; Pontecorvi A; Jochemsen AG; Moretti F
    Oncogene; 2002 Jan; 21(6):867-77. PubMed ID: 11840332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MDM2 promotes ubiquitination and degradation of MDMX.
    Pan Y; Chen J
    Mol Cell Biol; 2003 Aug; 23(15):5113-21. PubMed ID: 12860999
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A site-directed mutagenesis study of the MdmX RING domain.
    Egorova O; Mis M; Sheng Y
    Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX.
    Hu B; Gilkes DM; Chen J
    Cancer Res; 2007 Sep; 67(18):8810-7. PubMed ID: 17875722
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MDMX: a novel p53-binding protein with some functional properties of MDM2.
    Shvarts A; Steegenga WT; Riteco N; van Laar T; Dekker P; Bazuine M; van Ham RC; van der Houven van Oordt W; Hateboer G; van der Eb AJ; Jochemsen AG
    EMBO J; 1996 Oct; 15(19):5349-57. PubMed ID: 8895579
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mdmx promotes genomic instability independent of p53 and Mdm2.
    Carrillo AM; Bouska A; Arrate MP; Eischen CM
    Oncogene; 2015 Feb; 34(7):846-56. PubMed ID: 24608433
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity.
    He G; Zhang YW; Lee JH; Zeng SX; Wang YV; Luo Z; Dong XC; Viollet B; Wahl GM; Lu H
    Mol Cell Biol; 2014 Jan; 34(2):148-57. PubMed ID: 24190973
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53 regulation: teamwork between RING domains of Mdm2 and MdmX.
    Wang X
    Cell Cycle; 2011 Dec; 10(24):4225-9. PubMed ID: 22134240
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation.
    Xia M; Knezevic D; Tovar C; Huang B; Heimbrook DC; Vassilev LT
    Cell Cycle; 2008 Jun; 7(11):1604-12. PubMed ID: 18520179
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex: IMPLICATION OF A NOVEL MDMX SER-314 PHOSPHOSITE.
    Gerarduzzi C; de Polo A; Liu XS; El Kharbili M; Little JB; Yuan ZM
    J Biol Chem; 2016 Dec; 291(50):25937-25949. PubMed ID: 27777309
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2.
    Jin Y; Zeng SX; Sun XX; Lee H; Blattner C; Xiao Z; Lu H
    Mol Cell Biol; 2008 Feb; 28(4):1218-29. PubMed ID: 18086887
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.