BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

841 related articles for article (PubMed ID: 16227993)

  • 1. NKCC1 transporter facilitates seizures in the developing brain.
    Dzhala VI; Talos DM; Sdrulla DA; Brumback AC; Mathews GC; Benke TA; Delpire E; Jensen FE; Staley KJ
    Nat Med; 2005 Nov; 11(11):1205-13. PubMed ID: 16227993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
    Dzhala VI; Brumback AC; Staley KJ
    Ann Neurol; 2008 Feb; 63(2):222-35. PubMed ID: 17918265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures.
    Kahle KT; Staley KJ
    Neurosurg Focus; 2008 Sep; 25(3):E22. PubMed ID: 18759624
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy.
    Brandt C; Seja P; Töllner K; Römermann K; Hampel P; Kalesse M; Kipper A; Feit PW; Lykke K; Toft-Bertelsen TL; Paavilainen P; Spoljaric I; Puskarjov M; MacAulay N; Kaila K; Löscher W
    Neuropharmacology; 2018 Dec; 143():186-204. PubMed ID: 30248303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures.
    Glykys J; Dzhala VI; Kuchibhotla KV; Feng G; Kuner T; Augustine G; Bacskai BJ; Staley KJ
    Neuron; 2009 Sep; 63(5):657-72. PubMed ID: 19755108
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis.
    Dzhala V; Staley KJ
    CNS Neurosci Ther; 2015 Feb; 21(2):173-80. PubMed ID: 25495911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures.
    Cleary RT; Sun H; Huynh T; Manning SM; Li Y; Rotenberg A; Talos DM; Kahle KT; Jackson M; Rakhade SN; Berry G; Jensen FE
    PLoS One; 2013; 8(3):e57148. PubMed ID: 23536761
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Astrocytic NKCC1 inhibits seizures by buffering Cl
    Nguyen TD; Ishibashi M; Sinha AS; Watanabe M; Kato D; Horiuchi H; Wake H; Fukuda A
    Epilepsia; 2023 Dec; 64(12):3389-3403. PubMed ID: 37779224
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1.
    Kahle KT; Barnett SM; Sassower KC; Staley KJ
    J Child Neurol; 2009 May; 24(5):572-6. PubMed ID: 19406757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A combination of phenobarbital and the bumetanide derivative bumepamine prevents neonatal seizures and subsequent hippocampal neurodegeneration in a rat model of birth asphyxia.
    Johne M; Käufer C; Römermann K; Gailus B; Gericke B; Löscher W
    Epilepsia; 2021 Jun; 62(6):1460-1471. PubMed ID: 33955541
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vivo effects of bumetanide at brain concentrations incompatible with NKCC1 inhibition on newborn DGC structure and spontaneous EEG seizures following hypoxia-induced neonatal seizures.
    Wang S; Zhang XQ; Song CG; Xiao T; Zhao M; Zhu G; Zhao CS
    Neuroscience; 2015 Feb; 286():203-15. PubMed ID: 25463517
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus.
    Sivakumaran S; Maguire J
    Epilepsia; 2016 Feb; 57(2):222-32. PubMed ID: 26659482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of the NKCC1 inhibitors bumetanide, azosemide, and torasemide alone or in combination with phenobarbital on seizure threshold in epileptic and nonepileptic mice.
    Hampel P; Römermann K; Gailus B; Johne M; Gericke B; Kaczmarek E; Löscher W
    Neuropharmacology; 2021 Mar; 185():108449. PubMed ID: 33450274
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Blocking early GABA depolarization with bumetanide results in permanent alterations in cortical circuits and sensorimotor gating deficits.
    Wang DD; Kriegstein AR
    Cereb Cortex; 2011 Mar; 21(3):574-87. PubMed ID: 20624842
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus.
    Nardou R; Ben-Ari Y; Khalilov I
    J Neurophysiol; 2009 Jun; 101(6):2878-88. PubMed ID: 19297515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thermodynamic regulation of NKCC1-mediated Cl- cotransport underlies plasticity of GABA(A) signaling in neonatal neurons.
    Brumback AC; Staley KJ
    J Neurosci; 2008 Feb; 28(6):1301-12. PubMed ID: 18256250
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chloride cotransporter NKCC1 inhibitor bumetanide protects against white matter injury in a rodent model of periventricular leukomalacia.
    Jantzie LL; Hu MY; Park HK; Jackson MC; Yu J; Maxwell JR; Jensen FE
    Pediatr Res; 2015 Apr; 77(4):554-62. PubMed ID: 25585037
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility.
    Wang F; Wang X; Shapiro LA; Cotrina ML; Liu W; Wang EW; Gu S; Wang W; He X; Nedergaard M; Huang JH
    Brain Struct Funct; 2017 Apr; 222(3):1543-1556. PubMed ID: 27586142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy.
    Brandt C; Nozadze M; Heuchert N; Rattka M; Löscher W
    J Neurosci; 2010 Jun; 30(25):8602-12. PubMed ID: 20573906
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The loop diuretic torasemide but not azosemide potentiates the anti-seizure and disease-modifying effects of midazolam in a rat model of birth asphyxia.
    Welzel B; Schmidt R; Kirchhoff L; Gramer M; Löscher W
    Epilepsy Behav; 2023 Feb; 139():109057. PubMed ID: 36586153
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 43.