These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 16230620)

  • 1. A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
    Ratts R; Trujillo C; Bharti A; vanderSpek J; Harrison R; Murphy JR
    Proc Natl Acad Sci U S A; 2005 Oct; 102(43):15635-40. PubMed ID: 16230620
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trojan horse or proton force: finding the right partner(s) for toxin translocation.
    Trujillo C; Ratts R; Tamayo A; Harrison R; Murphy JR
    Neurotox Res; 2006 Apr; 9(2-3):63-71. PubMed ID: 16785102
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Essential lysine residues within transmembrane helix 1 of diphtheria toxin facilitate COPI binding and catalytic domain entry.
    Trujillo C; Taylor-Parker J; Harrison R; Murphy JR
    Mol Microbiol; 2010 May; 76(4):1010-9. PubMed ID: 20398220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process.
    Murphy JR
    Toxins (Basel); 2011 Mar; 3(3):294-308. PubMed ID: 22069710
    [TBL] [Abstract][Full Text] [Related]  

  • 5. COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro.
    Tamayo AG; Bharti A; Trujillo C; Harrison R; Murphy JR
    Proc Natl Acad Sci U S A; 2008 Apr; 105(13):5254-9. PubMed ID: 18356299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2.
    Hu HY; Huynh PD; Murphy JR; vanderSpek JC
    Protein Eng; 1998 Sep; 11(9):811-7. PubMed ID: 9796831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Maintenance of the hydrophobic face of the diphtheria toxin amphipathic transmembrane helix 1 is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
    vanderSpek JC; Howland K; Friedman T; Murphy JR
    Protein Eng; 1994 Aug; 7(8):985-9. PubMed ID: 7809038
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An intact transmembrane helix 9 is essential for the efficient delivery of the diphtheria toxin catalytic domain to the cytosol of target cells.
    vanderSpek J; Cassidy D; Genbauffe F; Huynh PD; Murphy JR
    J Biol Chem; 1994 Aug; 269(34):21455-9. PubMed ID: 8063778
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
    vanderSpek JC; Mindell JA; Finkelstein A; Murphy JR
    J Biol Chem; 1993 Jun; 268(16):12077-82. PubMed ID: 8505330
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells.
    Arora N; Leppla SH
    Infect Immun; 1994 Nov; 62(11):4955-61. PubMed ID: 7927776
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen.
    Blanke SR; Milne JC; Benson EL; Collier RJ
    Proc Natl Acad Sci U S A; 1996 Aug; 93(16):8437-42. PubMed ID: 8710889
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol.
    Falnes PO; Wiedłocha A; Rapak A; Olsnes S
    Biochemistry; 1995 Sep; 34(35):11152-9. PubMed ID: 7669773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex.
    Ratts R; Zeng H; Berg EA; Blue C; McComb ME; Costello CE; vanderSpek JC; Murphy JR
    J Cell Biol; 2003 Mar; 160(7):1139-50. PubMed ID: 12668662
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol.
    Stenmark H; Moskaug JO; Madshus IH; Sandvig K; Olsnes S
    J Cell Biol; 1991 Jun; 113(5):1025-32. PubMed ID: 2040642
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of the T-domain on intracellular transport of diphtheria toxin.
    Labyntsev AJ; Kolybo DV; Yurchenko ES; Kaberniuk AA; Korotkevych NV; Komisarenko SV
    Ukr Biochem J; 2014; 86(3):77-87. PubMed ID: 25033557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Extension of juxtamembrane domain of diphtheria toxin receptor arrests translocation of diphtheria toxin fragment A into cytosol.
    Takahashi T; Umata T; Mekada E
    Biochem Biophys Res Commun; 2001 Mar; 281(3):690-6. PubMed ID: 11237713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dynamic transitions of the transmembrane domain of diphtheria toxin: disulfide trapping and fluorescence proximity studies.
    Zhan H; Choe S; Huynh PD; Finkelstein A; Eisenberg D; Collier RJ
    Biochemistry; 1994 Sep; 33(37):11254-63. PubMed ID: 7537085
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Topography of helices 5-7 in membrane-inserted diphtheria toxin T domain: identification and insertion boundaries of two hydrophobic sequences that do not form a stable transmembrane hairpin.
    Rosconi MP; London E
    J Biol Chem; 2002 May; 277(19):16517-27. PubMed ID: 11859081
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EFFECT OF DIPHTHERIA TOXIN T-DOMAIN ON ENDOSOMAL pH.
    Labyntsev AJ; Korotkevych NV; Kolybo DV; Komisarenko SV
    Ukr Biochem J; 2015; 87(4):13-23. PubMed ID: 26547959
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width.
    Wang Y; Malenbaum SE; Kachel K; Zhan H; Collier RJ; London E
    J Biol Chem; 1997 Oct; 272(40):25091-8. PubMed ID: 9312118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.