191 related articles for article (PubMed ID: 16235238)
1. Rapid detection and characterization of minor reactive metabolites using stable-isotope trapping in combination with tandem mass spectrometry.
Yan Z; Maher N; Torres R; Caldwell GW; Huebert N
Rapid Commun Mass Spectrom; 2005; 19(22):3322-30. PubMed ID: 16235238
[TBL] [Abstract][Full Text] [Related]
2. Stable-isotope trapping and high-throughput screenings of reactive metabolites using the isotope MS signature.
Yan Z; Caldwell GW
Anal Chem; 2004 Dec; 76(23):6835-47. PubMed ID: 15571331
[TBL] [Abstract][Full Text] [Related]
3. Application of stable isotope labeled glutathione and rapid scanning mass spectrometers in detecting and characterizing reactive metabolites.
Mutlib A; Lam W; Atherton J; Chen H; Galatsis P; Stolle W
Rapid Commun Mass Spectrom; 2005; 19(23):3482-92. PubMed ID: 16261644
[TBL] [Abstract][Full Text] [Related]
4. Unbiased high-throughput screening of reactive metabolites on the linear ion trap mass spectrometer using polarity switch and mass tag triggered data-dependent acquisition.
Yan Z; Caldwell GW; Maher N
Anal Chem; 2008 Aug; 80(16):6410-22. PubMed ID: 18642850
[TBL] [Abstract][Full Text] [Related]
5. Improved detection of reactive metabolites with a bromine-containing glutathione analog using mass defect and isotope pattern matching.
Leblanc A; Shiao TC; Roy R; Sleno L
Rapid Commun Mass Spectrom; 2010 May; 24(9):1241-50. PubMed ID: 20391594
[TBL] [Abstract][Full Text] [Related]
6. Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.
Rousu T; Pelkonen O; Tolonen A
Rapid Commun Mass Spectrom; 2009 Mar; 23(6):843-55. PubMed ID: 19224530
[TBL] [Abstract][Full Text] [Related]
7. A generic method to detect electrophilic intermediates using isotopic pattern triggered data-dependent high-resolution accurate mass spectrometry.
Lim HK; Chen J; Cook K; Sensenhauser C; Silva J; Evans DC
Rapid Commun Mass Spectrom; 2008 Apr; 22(8):1295-311. PubMed ID: 18383206
[TBL] [Abstract][Full Text] [Related]
8. Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high-resolution mass spectrometry and mass defect filtering.
Zhu M; Ma L; Zhang H; Humphreys WG
Anal Chem; 2007 Nov; 79(21):8333-41. PubMed ID: 17918967
[TBL] [Abstract][Full Text] [Related]
9. A semiquantitative method for the determination of reactive metabolite conjugate levels in vitro utilizing liquid chromatography-tandem mass spectrometry and novel quaternary ammonium glutathione analogues.
Soglia JR; Contillo LG; Kalgutkar AS; Zhao S; Hop CE; Boyd JG; Cole MJ
Chem Res Toxicol; 2006 Mar; 19(3):480-90. PubMed ID: 16544956
[TBL] [Abstract][Full Text] [Related]
10. Rapid screening of glutathione-trapped reactive metabolites by linear ion trap mass spectrometry with isotope pattern-dependent scanning and postacquisition data mining.
Ma L; Wen B; Ruan Q; Zhu M
Chem Res Toxicol; 2008 Jul; 21(7):1477-83. PubMed ID: 18549250
[TBL] [Abstract][Full Text] [Related]
11. Rapid detection and characterization of in vitro and urinary N-acetyl-L-cysteine conjugates using quadrupole-linear ion trap mass spectrometry and polarity switching.
Jian W; Yao M; Zhang D; Zhu M
Chem Res Toxicol; 2009 Jul; 22(7):1246-55. PubMed ID: 19527004
[TBL] [Abstract][Full Text] [Related]
12. High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry.
Wen B; Ma L; Nelson SD; Zhu M
Anal Chem; 2008 Mar; 80(5):1788-99. PubMed ID: 18251522
[TBL] [Abstract][Full Text] [Related]
13. Screening and identification of GSH-trapped reactive metabolites using hybrid triple quadruple linear ion trap mass spectrometry.
Zheng J; Ma L; Xin B; Olah T; Humphreys WG; Zhu M
Chem Res Toxicol; 2007 May; 20(5):757-66. PubMed ID: 17402749
[TBL] [Abstract][Full Text] [Related]
14. Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites.
Yamaoka T; Kitamura Y
J Pharmacol Toxicol Methods; 2015; 76():83-95. PubMed ID: 26314789
[TBL] [Abstract][Full Text] [Related]
15. Thiazolidinedione bioactivation: a comparison of the bioactivation potentials of troglitazone, rosiglitazone, and pioglitazone using stable isotope-labeled analogues and liquid chromatography tandem mass spectrometry.
Alvarez-Sanchez R; Montavon F; Hartung T; Pähler A
Chem Res Toxicol; 2006 Aug; 19(8):1106-16. PubMed ID: 16918252
[TBL] [Abstract][Full Text] [Related]
16. High-throughput screening for glutathione conjugates using stable-isotope labeling and negative electrospray ionization precursor-ion mass spectrometry.
Liao S; Ewing NP; Boucher B; Materne O; Brummel CL
Rapid Commun Mass Spectrom; 2012 Mar; 26(6):659-69. PubMed ID: 22328220
[TBL] [Abstract][Full Text] [Related]
17. High-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.
Barbara JE; Castro-Perez JM
Rapid Commun Mass Spectrom; 2011 Oct; 25(20):3029-40. PubMed ID: 21953957
[TBL] [Abstract][Full Text] [Related]
18. Screening strategy for the rapid detection of in vitro generated glutathione conjugates using high-performance liquid chromatography and low-resolution mass spectrometry in combination with LightSight software for data processing.
Ramírez-Molina C; Burton L
Rapid Commun Mass Spectrom; 2009 Nov; 23(22):3501-12. PubMed ID: 19844970
[TBL] [Abstract][Full Text] [Related]
19. Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites.
Damsten MC; van Vugt-Lussenburg BM; Zeldenthuis T; de Vlieger JS; Commandeur JN; Vermeulen NP
Chem Biol Interact; 2008 Jan; 171(1):96-107. PubMed ID: 17996858
[TBL] [Abstract][Full Text] [Related]
20. Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism.
Madsen KG; Olsen J; Skonberg C; Hansen SH; Jurva U
Chem Res Toxicol; 2007 May; 20(5):821-31. PubMed ID: 17447796
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]